MGDP1_YEAST - dbPTM
MGDP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MGDP1_YEAST
UniProt AC P40081
Protein Name Putative magnesium-dependent phosphatase YER134C
Gene Name YER134C
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 178
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Magnesium-dependent phosphatase which may act as a tyrosine phosphatase..
Protein Sequence MTGYPDVAAFDLDYTIWPCYCDTHLHGPFKPVKSSNGEVLTIICRDGYELTIYKDIPRILGDLKDNGVKLMTASRTWAPEIAQEILKIFKVKYAGVVTPLANLFDEFQWGERSKIGHLRDGLKDLYNTSDLKSKKICLFDDESRNKEVEKYGVKFVYVRDPENGPSWKLYQDYLSGKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41PhosphorylationSSNGEVLTIICRDGY
CCCCCEEEEEECCCE		17.3028889911
64AcetylationPRILGDLKDNGVKLM
HHHHHCHHHCCEEEE		54.6225381059
64SuccinylationPRILGDLKDNGVKLM
HHHHHCHHHCCEEEE		54.6223954790
123AcetylationGHLRDGLKDLYNTSD
CHHHHHHHHHHCCCC		51.7424489116
123SuccinylationGHLRDGLKDLYNTSD
CHHHHHHHHHHCCCC		51.7423954790
132SuccinylationLYNTSDLKSKKICLF
HHCCCCCCCCEEEEE		66.2823954790
151PhosphorylationRNKEVEKYGVKFVYV
HCHHHHHHCEEEEEE		17.4122369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MGDP1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MGDP1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MGDP1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATG7_YEASTATG7physical
18719252
SSD1_YEASTSSD1genetic
19269370
ECM33_YEASTECM33genetic
27708008
PP2C4_YEASTPTC4genetic
27708008
YCA2_YEASTYCL002Cgenetic
27708008
BUD31_YEASTBUD31genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
CTH1_YEASTCTH1genetic
27708008
MTO1_YEASTMTO1genetic
27708008
ARP1_YEASTARP1genetic
27708008
NCA3_YEASTNCA3genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
AEP2_YEASTAEP2genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
MDM12_YEASTMDM12genetic
27708008
TCB1_YEASTTCB1genetic
27708008
LIPA_YEASTLIP5genetic
27708008
NUP60_YEASTNUP60genetic
27708008
PFF1_YEASTPFF1genetic
27708008
SMY2_YEASTSMY2genetic
27708008
HPC2_YEASTHPC2genetic
27708008
VHC1_YEASTVHC1genetic
27708008
DCC1_YEASTDCC1genetic
27708008
STE50_YEASTSTE50genetic
27708008
THRC_YEASTTHR4genetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
RPN4_YEASTRPN4genetic
27708008
MTU1_YEASTSLM3genetic
27708008
ATG20_YEASTATG20genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
MFG1_YEASTMFG1genetic
27708008
MIX14_YEASTMIX14genetic
27708008
SAC3_YEASTSAC3genetic
27708008
TRM82_YEASTTRM82genetic
27708008
MNN10_YEASTMNN10genetic
27708008
MCM21_YEASTMCM21genetic
27708008
YFF2_YEASTYFL052Wgenetic
27708008
SGF73_YEASTSGF73genetic
27708008
CLG1_YEASTCLG1genetic
27708008
DBF2_YEASTDBF2genetic
27708008
BIOB_YEASTBIO2genetic
27708008
CTF8_YEASTCTF8genetic
27708008
ATG32_YEASTATG32genetic
27708008
SGN1_YEASTSGN1genetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
YKE44_YEASTYKL044Wgenetic
27708008
FABG_YEASTOAR1genetic
27708008
MSN4_YEASTMSN4genetic
27708008
PIR3_YEASTPIR3genetic
27708008
YRA2_YEASTYRA2genetic
27708008
RIC1_YEASTRIC1genetic
27708008
SRL2_YEASTSRL2genetic
27708008
MMR1_YEASTMMR1genetic
27708008
POC1_YEASTPBA1genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
SPH1_YEASTSPH1genetic
27708008
VPS38_YEASTVPS38genetic
27708008
GAL80_YEASTGAL80genetic
27708008
CTF18_YEASTCTF18genetic
27708008
AIP1_YEASTAIP1genetic
27708008
MLH1_YEASTMLH1genetic
27708008
SSO2_YEASTSSO2genetic
27708008
GCSP_YEASTGCV2genetic
27708008
COX7_YEASTCOX7genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
OCA1_YEASTOCA1genetic
27708008
VPS27_YEASTVPS27genetic
27708008
IZH2_YEASTIZH2genetic
27708008
INO4_YEASTINO4genetic
27708008
BUB3_YEASTBUB3genetic
27708008
DIA2_YEASTDIA2genetic
27708008
FABD_YEASTMCT1genetic
27708008
CTF19_YEASTCTF19genetic
27708008
RAD1_YEASTRAD1genetic
27708008
LPE10_YEASTMFM1genetic
27708008
PXA1_YEASTPXA1genetic
27708008
FUMH_YEASTFUM1genetic
27708008
SAM4_YEASTSAM4genetic
27708008
KAR3_YEASTKAR3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MGDP1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-41, AND MASSSPECTROMETRY.

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