dbPTM

MTO1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MTO1_YEAST
UniProt AC	P53070
Protein Name	Mitochondrial translation optimization protein 1
Gene Name	MTO1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	669
Subcellular Localization	Mitochondrion .
Protein Description	Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs..
Protein Sequence	MLRVTTLASSCTSFPLQVLRRRLTISSLTSFQPTTKTQVVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDPGCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYGISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGAQLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEIFRFKDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQLPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of MTO1_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MTO1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MTO1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MTO1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SKI2_YEAST	SKI2	genetic	19061648
SYKC_YEAST	KRS1	genetic	19061648
ERF3_YEAST	SUP35	genetic	19061648
SYC1_YEAST	SYC1	genetic	19061648
APQ12_YEAST	APQ12	genetic	19061648
NU100_YEAST	NUP100	genetic	19061648
PAP2_YEAST	PAP2	genetic	19061648
PABP_YEAST	PAB1	genetic	19061648
MTU1_YEAST	SLM3	genetic	20004207
SWD1_YEAST	SWD1	genetic	20093466
HSP30_YEAST	HSP30	genetic	20093466
UBX3_YEAST	UBX3	genetic	20093466
ODO2_YEAST	KGD2	genetic	20093466
IPK1_YEAST	IPK1	genetic	20093466
OMS1_YEAST	OMS1	genetic	20093466
HPRT_YEAST	HPT1	genetic	20093466
POLH_YEAST	RAD30	genetic	20093466
CEM1_YEAST	CEM1	genetic	20093466
SPR3_YEAST	SPR3	genetic	20093466
PBP1_YEAST	PBP1	genetic	20093466
OYE2_YEAST	OYE2	genetic	20093466
ADY1_YEAST	PFS1	genetic	20093466
VID28_YEAST	VID28	genetic	20093466
LSM1_YEAST	LSM1	genetic	20093466
GPI7_YEAST	LAS21	genetic	20093466
CAF4_YEAST	CAF4	genetic	20093466
YK104_YEAST	YKR104W	genetic	20093466
UBI4P_YEAST	UBI4	genetic	20093466
RAX2_YEAST	RAX2	genetic	20093466
EXG1_YEAST	EXG1	genetic	20093466
SOK2_YEAST	SOK2	genetic	20093466
MSS1_YEAST	MSS1	genetic	20093466
PEX12_YEAST	PEX12	genetic	20093466
AVO2_YEAST	AVO2	genetic	20093466
PFKA2_YEAST	PFK2	genetic	20093466
YM60_YEAST	YMR210W	genetic	20093466
PHO23_YEAST	PHO23	genetic	20093466
NST1_YEAST	NST1	genetic	20093466
VPS27_YEAST	VPS27	genetic	20093466
HOL1_YEAST	HOL1	genetic	20093466
YPQ1_YEAST	YPQ1	genetic	20093466
IRA2_YEAST	IRA2	genetic	20093466
PSK2_YEAST	PSK2	genetic	20093466
SFL1_YEAST	SFL1	genetic	20093466
PDE2_YEAST	PDE2	genetic	20093466
DDC1_YEAST	DDC1	genetic	20093466
YP150_YEAST	YPL150W	genetic	20093466
JID1_YEAST	JID1	genetic	20093466
SPEE_YEAST	SPE3	genetic	20093466
MED1_YEAST	MED1	genetic	20093466
CND2_YEAST	BRN1	genetic	27708008
RPN12_YEAST	RPN12	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
NUP57_YEAST	NUP57	genetic	27708008
MCM1_YEAST	MCM1	genetic	27708008
DAL81_YEAST	DAL81	genetic	27708008
IME1_YEAST	IME1	genetic	27708008
PRP6_YEAST	PRP6	genetic	27708008
TAF5_YEAST	TAF5	genetic	27708008
TECR_YEAST	TSC13	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
HEM6_YEAST	HEM13	genetic	27708008
NSE3_YEAST	NSE3	genetic	27708008
TFB1_YEAST	TFB1	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
HSF_YEAST	HSF1	genetic	27708008
TEL2_YEAST	TEL2	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
ESS1_YEAST	ESS1	genetic	27708008
ABF1_YEAST	ABF1	genetic	27708008
SN114_YEAST	SNU114	genetic	27708008
PRP19_YEAST	PRP19	genetic	27708008
RSC9_YEAST	RSC9	genetic	27708008
UTP15_YEAST	UTP15	genetic	27708008
CH10_YEAST	HSP10	genetic	27708008
TYSY_YEAST	CDC21	genetic	27708008
DYR_YEAST	DFR1	genetic	27708008
MOT1_YEAST	MOT1	genetic	27708008
RPN7_YEAST	RPN7	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
ELO2_YEAST	ELO2	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
UBCX_YEAST	PEX4	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
PEX13_YEAST	PEX13	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
IRA2_YEAST	IRA2	genetic	27708008
VAM10_YEAST	VAM10	genetic	27708008
PDE2_YEAST	PDE2	genetic	27708008
BECN1_YEAST	VPS30	genetic	27708008
SPEE_YEAST	SPE3	genetic	27708008
MED1_YEAST	MED1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MTO1_YEAST

Related Literatures of Post-Translational Modification