BIOB_YEAST - dbPTM
BIOB_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BIOB_YEAST
UniProt AC P32451
Protein Name Biotin synthase, mitochondrial
Gene Name BIO2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 375
Subcellular Localization Mitochondrion .
Protein Description
Protein Sequence MMSTIYRHLSTARPALTKYATNAAVKSTTASSEASTLGALQYALSLDEPSHSWTKSQLKEIYHTPLLELTHAAQLQHRKWHDPTKVQLCTLMNIKSGGCSEDCKYCAQSSRNDTGLKAEKMVKVDEVIKEAEEAKRNGSTRFCLGAAWRDMKGRKSAMKRIQEMVTKVNDMGLETCVTLGMVDQDQAKQLKDAGLTAYNHNIDTSREHYSKVITTRTYDDRLQTIKNVQESGIKACTGGILGLGESEDDHIGFIYTLSNMSPHPESLPINRLVAIKGTPMAEELADPKSKKLQFDEILRTIATARIVMPKAIIRLAAGRYTMKETEQFVCFMAGCNSIFTGKKMLTTMCNGWDEDKAMLAKWGLQPMEAFKYDRS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
59AcetylationSWTKSQLKEIYHTPL
CCCHHHHHHHHCCHH
34.1324489116
291AcetylationLADPKSKKLQFDEIL
HCCCCCCCCCHHHHH
55.3922865919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BIOB_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BIOB_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BIOB_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
OAF3_YEASTOAF3physical
16554755
MOT3_YEASTMOT3physical
18719252
GDIR_YEASTRDI1genetic
20093466
SLX5_YEASTSLX5genetic
20093466
NHP10_YEASTNHP10genetic
20093466
VPS41_YEASTVPS41genetic
20093466
SSD1_YEASTSSD1genetic
20093466
WWM1_YEASTWWM1genetic
20093466
PEF1_YEASTPEF1genetic
20093466
YIT6_YEASTYIR016Wgenetic
20093466
BCK1_YEASTBCK1genetic
20093466
YJE9_YEASTYJL049Wgenetic
20093466
YJ24_YEASTKCH1genetic
20093466
ATG3_YEASTATG3genetic
20093466
TRM11_YEASTTRM11genetic
20093466
MSN1_YEASTMSN1genetic
20093466
LIPA_YEASTLIP5genetic
20093466
DGK1_YEASTDGK1genetic
20093466
SYH1_YEASTSYH1genetic
20093466
THDH_YEASTILV1genetic
21623372
HTD2_YEASTHTD2genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
ARO1_YEASTARO1genetic
21623372
SDHB_YEASTSDH2genetic
21623372
BCK1_YEASTBCK1genetic
22282571
NOP14_YEASTNOP14genetic
27708008
LCB2_YEASTLCB2genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
SMT3_YEASTSMT3genetic
27708008
RSP5_YEASTRSP5genetic
27708008
ACT_YEASTACT1genetic
27708008
MPPA_YEASTMAS2genetic
27708008
MED6_YEASTMED6genetic
27708008
CDC12_YEASTCDC12genetic
27708008
SMC4_YEASTSMC4genetic
27708008
SEC22_YEASTSEC22genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
LCB1_YEASTLCB1genetic
27708008
RPA1_YEASTRPA190genetic
27708008
DIM1_YEASTDIM1genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
SLX5_YEASTSLX5genetic
27708008
YD061_YEASTYDR061Wgenetic
27708008
LSM6_YEASTLSM6genetic
27708008
RV167_YEASTRVS167genetic
27708008
WWM1_YEASTWWM1genetic
27708008
SGF73_YEASTSGF73genetic
27708008
ECT1_YEASTECT1genetic
27708008
PEF1_YEASTPEF1genetic
27708008
LPLA_YEASTAIM22genetic
27708008
YJE9_YEASTYJL049Wgenetic
27708008
BCK1_YEASTBCK1genetic
27708008
YJ24_YEASTKCH1genetic
27708008
FABG_YEASTOAR1genetic
27708008
LIPB_YEASTLIP2genetic
27708008
GBLP_YEASTASC1genetic
27708008
TOM70_YEASTTOM70genetic
27708008
LSM7_YEASTLSM7genetic
27708008
ATG3_YEASTATG3genetic
27708008
MSN1_YEASTMSN1genetic
27708008
TRM11_YEASTTRM11genetic
27708008
DIA2_YEASTDIA2genetic
27708008
LIPA_YEASTLIP5genetic
27708008
PMA2_YEASTPMA2genetic
27708008
SYH1_YEASTSYH1genetic
27708008
VPS4_YEASTVPS4genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BIOB_YEAST

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Related Literatures of Post-Translational Modification

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