TOM20_YEAST - dbPTM
TOM20_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TOM20_YEAST
UniProt AC P35180
Protein Name Mitochondrial import receptor subunit TOM20
Gene Name TOM20
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 183
Subcellular Localization Mitochondrion outer membrane
Single-pass membrane protein .
Protein Description Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore..
Protein Sequence MSQSNPILRGLAITTAIAALSATGYAIYFDYQRRNSPQFRKVLRQRAKEQAKMEEQAKTHAKEVKLQKVTEFLSMELAKDPIPSDPSEREATFTTNVENGERLSMQQGKELEAASKFYKALTVYPQPADLLGIYQRSIPEAIYEYIILMIAILPPANVASFVKGVVGSKAESDAVAEANDIDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
36PhosphorylationFDYQRRNSPQFRKVL
HCHHHCCCHHHHHHH		20.4727214570
84PhosphorylationLAKDPIPSDPSEREA
HHCCCCCCCHHHCCC		63.9730377154
87PhosphorylationDPIPSDPSEREATFT
CCCCCCHHHCCCEEE		55.0324909858
109UbiquitinationRLSMQQGKELEAASK
EECHHHCCHHHHHHH		55.5823749301
109AcetylationRLSMQQGKELEAASK
EECHHHCCHHHHHHH		55.5824489116
116AcetylationKELEAASKFYKALTV
CHHHHHHHHHHHHHH		48.2424489116
119UbiquitinationEAASKFYKALTVYPQ
HHHHHHHHHHHHCCC		39.8024961812
122PhosphorylationSKFYKALTVYPQPAD
HHHHHHHHHCCCHHH		23.8927017623
124PhosphorylationFYKALTVYPQPADLL
HHHHHHHCCCHHHHH		7.3027017623
168PhosphorylationFVKGVVGSKAESDAV
HHHHHHCCCHHHHHH		19.6524961812
169UbiquitinationVKGVVGSKAESDAVA
HHHHHCCCHHHHHHH		50.6923749301
172PhosphorylationVVGSKAESDAVAEAN
HHCCCHHHHHHHHHH		35.4119823750
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TOM20_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TOM20_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TOM20_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TOM40_YEASTTOM40physical
11276259
TOM22_YEASTTOM22physical
10519552
TOM40_YEASTTOM40physical
10519552
TOM22_YEASTTOM22physical
9774667
VDAC1_YEASTPOR1physical
11266446
TOM22_YEASTTOM22physical
8754801
TOM70_YEASTTOM70genetic
8223428
TOM70_YEASTTOM70genetic
7760834
TOM70_YEASTTOM70physical
8635455
TOM22_YEASTTOM22physical
8635455
VMA22_YEASTVMA22physical
18467557
ALO_YEASTALO1physical
18467557
COG2_YEASTCOG2physical
18719252
PUF3_YEASTPUF3genetic
19858288
DYN3_YEASTDYN3physical
16093310
PET8_YEASTPET8physical
16093310
TOM22_YEASTTOM22genetic
7760834
UPS2_YEASTUPS2physical
20622808
TOM20_YEASTTOM20physical
22940862
ATP9_NEUCRNCU02250physical
21173275
MIM1_YEASTMIM1physical
23959800
PEX14_YEASTPEX14physical
26644516
ATC3_YEASTDRS2genetic
27708008
MNN10_YEASTMNN10genetic
27708008
MIC60_YEASTMIC60genetic
27708008
CND2_YEASTBRN1genetic
27708008
PRP6_YEASTPRP6genetic
27708008
CDC4_YEASTCDC4genetic
27708008
SAM35_YEASTSAM35genetic
27708008
CDC12_YEASTCDC12genetic
27708008
HACD_YEASTPHS1genetic
27708008
CWC16_YEASTYJU2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TIM23_YEASTTIM23genetic
27708008
CLP1_YEASTCLP1genetic
27708008
MYO2_YEASTMYO2genetic
27708008
TIM50_YEASTTIM50genetic
27708008
RXT2_YEASTRXT2genetic
27708008
SWC5_YEASTSWC5genetic
27708008
SSH1_YEASTSSH1genetic
27708008
BIK1_YEASTBIK1genetic
27708008
APA1_YEASTAPA1genetic
27708008
RV161_YEASTRVS161genetic
27708008
BUD31_YEASTBUD31genetic
27708008
GET3_YEASTGET3genetic
27708008
CYK3_YEASTCYK3genetic
27708008
YD157_YEASTYDL157Cgenetic
27708008
TGL2_YEASTTGL2genetic
27708008
CHL4_YEASTCHL4genetic
27708008
SDS3_YEASTSDS3genetic
27708008
DAL81_YEASTDAL81genetic
27708008
MGA2_YEASTMGA2genetic
27708008
SFH5_YEASTSFH5genetic
27708008
MPCP_YEASTMIR1genetic
27708008
ACF4_YEASTACF4genetic
27708008
MDM35_YEASTMDM35genetic
27708008
PAM17_YEASTPAM17genetic
27708008
DNM1_YEASTDNM1genetic
27708008
ENV10_YEASTENV10genetic
27708008
XDJ1_YEASTXDJ1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
DCR2_YEASTDCR2genetic
27708008
ATP10_YEASTATP10genetic
27708008
UBX2_YEASTUBX2genetic
27708008
MUB1_YEASTMUB1genetic
27708008
SCS7_YEASTSCS7genetic
27708008
PUB1_YEASTPUB1genetic
27708008
TOM7_YEASTTOM7genetic
27708008
TOM70_YEASTTOM70genetic
27708008
SIN3_YEASTSIN3genetic
27708008
MDM12_YEASTMDM12genetic
27708008
HST1_YEASTHST1genetic
27708008
TOM6_YEASTTOM6genetic
27708008
PIP2_YEASTPIP2genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
UME1_YEASTUME1genetic
27708008
RTC6_YEASTRTC6genetic
27708008
STI1_YEASTSTI1physical
27412066
HSP71_YEASTSSA1physical
27412066
HSP82_YEASTHSP82physical
27412066
SIS1_YEASTSIS1physical
27412066
MAS5_YEASTYDJ1physical
27412066
NDC80_HUMANNDC80physical
27107014
SGTA_HUMANSGTAphysical
27107014
CEP55_HUMANCEP55physical
27107014
CEP70_HUMANCEP70physical
27107014
SRTD1_HUMANSERTAD1physical
27107014
USBP1_HUMANUSHBP1physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TOM20_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-172, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory