SAM35_YEAST - dbPTM
SAM35_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SAM35_YEAST
UniProt AC P14693
Protein Name Sorting assembly machinery 35 kDa subunit
Gene Name SAM35
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 329
Subcellular Localization Mitochondrion outer membrane .
Protein Description Essential component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex..
Protein Sequence MVSSFSVPMPVKRIFDTFPLQTYAAQTDKDEAVALEIQRRSYTFTERGGGSSELTVEGTYKLGVYNVFLEANTGAALATDPWCLFVQLALCQKNGLVLPTHSQEQTPSHTCNHEMLVLSRLSNPDEALPILVEGYKKRIIRSTVAISEIMRSRILDDAEQLMYYTLLDTVLYDCWITQIIFCASDAQFMELYSCQKLSGSIVTPLDVENSLLQKLSAKSLKISLTKRNKFQFRHREIVKSMQGVYHNHHNSVNQEQVLNVLFENSKQVLLGLKDMLKSDGQPTYLHLKIASYILCITNVKEPIKLKTFVENECKELVQFAQDTLKNFVQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MVSSFSVPMP
-----CCCCCCCCCC		25.1128889911
4Phosphorylation----MVSSFSVPMPV
----CCCCCCCCCCC		15.3219823750
6Phosphorylation--MVSSFSVPMPVKR
--CCCCCCCCCCCCC		27.5319795423
42PhosphorylationLEIQRRSYTFTERGG
HEEEEEEEEEEECCC		12.2219779198
45PhosphorylationQRRSYTFTERGGGSS
EEEEEEEEECCCCCC		19.5719779198
59PhosphorylationSELTVEGTYKLGVYN
CEEEEEEEEEEECEE		12.1819779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseSAN1P22470
PMID:32118579
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SAM35_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SAM35_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPC19_YEASTSPC19physical
10688190
CARME_YEASTYNL092Wphysical
10688190
SAM37_YEASTSAM37physical
15205677
SAM50_YEASTSAM50physical
15205677
SAM50_YEASTSAM50physical
15590639
SAM37_YEASTSAM37physical
15590639
SAM50_YEASTSAM50physical
17410204
SAM37_YEASTSAM37physical
17410204
MDM10_YEASTMDM10physical
17410204
ALO_YEASTALO1physical
18467557
TOM40_YEASTTOM40physical
18358813
SAM37_YEASTSAM37genetic
17978093
MDM10_YEASTMDM10genetic
20093466
SIF2_YEASTSIF2genetic
20093466
RT103_YEASTRTT103genetic
20093466
RLA4_YEASTRPP2Bgenetic
20093466
SXM1_YEASTSXM1genetic
20093466
RL27B_YEASTRPL27Bgenetic
20093466
MZM1_YEASTMZM1genetic
20093466
PP2C2_YEASTPTC2genetic
20093466
TIM13_YEASTTIM13genetic
20093466
DHOM_YEASTHOM6genetic
20093466
BPT1_YEASTBPT1genetic
20093466
SAM37_YEASTSAM37genetic
20093466
GID8_YEASTGID8genetic
20093466
ADE_YEASTAAH1genetic
20093466
MED9_YEASTCSE2genetic
20093466
COQ2_YEASTCOQ2genetic
20093466
MDM12_YEASTMDM12genetic
20093466
SYC1_YEASTSYC1genetic
20093466
PNT1_YEASTPNT1genetic
20093466
VPH1_YEASTVPH1genetic
20093466
PALA_YEASTRIM20genetic
20093466
RS10A_YEASTRPS10Agenetic
20093466
NIP80_YEASTNIP100genetic
20093466
MRX11_YEASTYPL041Cgenetic
20093466
KAR3_YEASTKAR3genetic
20093466
SAM50_YEASTSAM50physical
20111053
SAM35_YEASTSAM35physical
20111053
SAM37_YEASTSAM37physical
20111053
MDM10_YEASTMDM10physical
20111053
TOM40_YEASTTOM40physical
21036907
MDM10_YEASTMDM10physical
20026336
TOM40_YEASTTOM40physical
20026336
TOM5_YEASTTOM5physical
20026336
SAM50_YEASTSAM50physical
21680715
SAM37_YEASTSAM37physical
21680715
MDM10_YEASTMDM10physical
21680715
VDAC1_YEASTPOR1physical
21680715
TOM40_YEASTTOM40physical
21680715
MDM12_YEASTMDM12physical
21680715
TIM23_YEASTTIM23physical
21680715
HSP77_YEASTSSC1physical
21680715
TOM22_YEASTTOM22physical
21680715
MIM1_YEASTMIM1physical
21680715
ALO_YEASTALO1physical
22615397
DCP2_YEASTDCP2genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
YME1_YEASTYME1genetic
27708008
SP110_YEASTSPC110genetic
27708008
NOP56_YEASTNOP56genetic
27708008
PRP24_YEASTPRP24genetic
27708008
NAB3_YEASTNAB3genetic
27708008
NIP7_YEASTNIP7genetic
27708008
CP56_YEASTDIT2genetic
27708008
MDM34_YEASTMDM34genetic
27708008
CTK1_YEASTCTK1genetic
27708008
SAM37_YEASTSAM37genetic
27708008
MDM12_YEASTMDM12genetic
27708008
RTC1_YEASTRTC1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
MDM10_YEASTMDM10genetic
29674565
GEM1_YEASTGEM1genetic
29674565
CHO2_YEASTCHO2genetic
29674565
TIM13_YEASTTIM13genetic
29674565
CDC73_YEASTCDC73genetic
29674565
ATPN_YEASTATP20genetic
29674565
MAK5_YEASTMAK5genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SAM35_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory