CCM1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCM1_YEAST
• UniProt AC: P48237
• Protein Name: Mitochondrial group I intron splicing factor CCM1
• Gene Name: CCM1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 864
• Subcellular Localization: Mitochondrion .
• Protein Description: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome..
• Protein Sequence: MYMARCGPKNNVLCFPFQLSFLFSKRLINKRFKYTLQTEDEKNMMGSLSKNKIITPEDVEFKLAQLREFSNTLKERIHNTKSVNSDGHQSNSIAPISEDSRNVNVTKTSSVPNEEKSKNLSDLIHSSFLEKMDHLVPKVIRERVADDDILAKNLFDRSHSNWAPVIDRLYVSEKRFMDIDSREFSVWLNGTVKYLPFHSILHLDEMLLEQINGDVVKFNTHMYECIFNNLGNLKPTNFNQDGTNDKVILKMKELLERYDKALKITEERINKKEGFPSKVPKMTQAILNNCLKYSTKCSSFHDMDYFITKFRDDYGITPNKQNLTTVIQFYSRKEMTKQAWNTFDTMKFLSTKHFPDICTYNTMLRICEKERNFPKALDLFQEIQDHNIKPTTNTYIMMARVLASSSSNAVVSEGKSDSLRLLGWKYLHELEDKNLYRHKKDDLNLFLAMMALAAFDGDIELSRALYYLFIAKKYKTLCANWKGNILVDQDTIWKSTLMPEMLNYLMLAYARFDPRNLPVLSGYEKGIELRRKFLREFDSSMRLDDTDKLVKFKLPFLPISDLNSEAQVLAESNAIWSFNMENGGTRNTLTSSNEAALEDIKKYRQLLDSFAQEAEDFNEFKFKVMYEVTKMQRESINVNVFNKISLHTYLSIPINLKQQKEFLRRLTFFTFQQHEFEAVIKRLYEGYRNIPSSHTRDQNSISTEAISVSKPETTEDLNLIMHDIWYITCLRHKIMMDTTLYELVMKAAIEFQNEDLAKKVWNDRGKFRTTVPFLKMDQRIRIAKDQKFAHLMVEFFTKQGKYSDAIAIILSSKNRFNWTYSMVRNLHKALEEIEDRNSVEILLDVVNKKSHAKALKWEEQELNM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Phosphorylation	HNTKSVNSDGHQSNS HCCCCCCCCCCCCCC	42.70	19779198
97	Phosphorylation	SNSIAPISEDSRNVN CCCCCCCCCCCCCCC	34.00	19779198
404	Phosphorylation	MMARVLASSSSNAVV HHHHHHHCCCCCCEE	26.96	28889911
405	Phosphorylation	MARVLASSSSNAVVS HHHHHHCCCCCCEEC	31.98	28889911
406	Phosphorylation	ARVLASSSSNAVVSE HHHHHCCCCCCEECC	25.72	28889911
407	Phosphorylation	RVLASSSSNAVVSEG HHHHCCCCCCEECCC	30.65	28889911
412	Phosphorylation	SSSNAVVSEGKSDSL CCCCCEECCCCHHHH	33.75	28889911
416	Phosphorylation	AVVSEGKSDSLRLLG CEECCCCHHHHHHHC	43.20	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCM1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCM1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCM1_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of CCM1_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.