| UniProt ID | YP117_YEAST | |
|---|---|---|
| UniProt AC | Q06116 | |
| Protein Name | Uncharacterized protein YPR117W | |
| Gene Name | YPR117W | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 2489 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MSMLPWSQIRDVSKLLLGFMLFIISIQKIASILMSWILMLRHSTIRKISFGYFFGTSIRRAFILTDFAQIYIGKITLRIGWKPGIVFHNVDLKLFGKDSHITAHSTKDSRTYFNPRDQTFTFVINRRVLSILKLVFSFSTFFHTLALTVPNGKQYKLNIGSITISHPHDDTIKLEAFLHDFTHPETKDTLNHTGFFMVCKIGKEDDTGSNCTKVILKNWKSSLKISDVCWHLPEKKGKNLHSEPVEPFSAGDDAEMLTSYRKMLKPFHYPLKTLNILDLKVENVKLIYKKKFTIRISSAQLYLESISILNNVSALELLPLNKPTWGDFELSLSANAVVVDIDGNTAVRIPFGNVILTSDILLFLLDNVPLRRTKVSSILNIINPSVFLTIHQVLEVLHLVDKFDSPETSSCTNTNDRSLNILDLDIDRLPSFNFELLMSNFISRLHISDEENVTFKVFSTHALFSRNNLSMTPKKGQVMQIRPDWPFAKTALVSDQLSNYIKIVGTSLSYLRIPTEQDANPVSIPVCGFERLDTFLDEFSNSKLIVQSTLRHSYVSLENIEVLHTLSRAFDKIYLLISSRTKRNAAHKANGGKLGDLNEAKKTFNWSLKLRMKDISCSLLVAGFLPKNLDPVEAENFNLSDVTRGAKVVFTESILLADSQEKNFTIIDASVYRFMDGTTYKPSPEVIIQFTNLLLSFNDSDEIHFSLPKIKFKMDVNIIWLWFYIRSIWIKFRPNSKLSRNSVSSVKSVNVLDRLRVDIGKMIIELTLPHNTEVLLIFERIGLSSSTKNLTIASLSAYVVSVYVKHIKVYVSLLNINDFELDTEELICKKSAVINTSLIHFHAEYHFRFYMITDNIVTLYKSFKQIKLAFSNLNEFKRLYPQQQFPKKVPNLHICCQDFLIDIEEDPFEQELGLILKVGVLEQRERLKKLEEFKEKLSTYEDMNVRLRSLYDTSRGQSFFPEFYANDQEYEQKAYLRLLENFSTSWIARYRKAKLSFYGMPYRVISREELGTKYHLFTRQKTSTVANLVVKDLDFKLGSPSFPLDNYMDFVYQYGKKVPKSTEYTLLIILGLKIKSALWELRLRDYPIPAISFPDTFTTGDVVFAEKMPAPCALHTVYVPFVSSAQRSPYNDANTIYGLHIIRTINSVKTYFNIRSMVTSSSSARITWGKSLQPGYESLMLWFDFLTKPLIDPSKKLGFWDKFRYLVHGKWIYEFSEESEIHLNIKGSHDPYKITDDGAGLAFCWSGGTTIYVHNSTDPKEFLKIESQRFQLAVPDFAKVSKFDKVFMKLDGRVIWTLGLLFEQGDISKAGDEERFLPNRPHYEIQLMNPDGVADLDHHDTYKGFRTSFIHMSFGVYSSEHGSINSLYLAPYALTHFFKWWNLFHTYTSGPIRQGRLFTDVLQNKTKFGRSLFTIAYQLHLKRLMVTHIYRHITTQYDLEKDRKITFTGLKGRFDSLKIDLHQKRVKLTHTNQKLNKSKPVWKFKMSRGEIDCAEADIRILSTLFDQEAVKEILTSGLDGILEDEPSRPITPQDVEYLRESDWYDYEDYIDLNQVPLGSSLPLKLEAIPLLYSPRISYFRKINDDGYVLAYPFGTEESHNCLIGKNHPELTQEKLATERKREIEEQLKLLHITLSELQSNKGGGSVSGNSERYARELKAEVAELNHRLHTVNTILSDLKISETIPGGNTDGDSSSSLSDTDVNLENAPPIQNRISLLRTNTVESFVSMRKASTMQVESTYDNRFMVHNIELKIDNKIRHHLLEYASSAFERKSMRFAVTYKSVTILKELLGNVLTGVRTSVEDYGSILEDDLASNSEFIEHFEKLIREVPSDDFDYVDNYLFRLISPQVQIKSDVERNAAVILAARDIEMGIIDIVQVYGKSGKRIPVDVDTIVETRYSAVSKDIQLFTLFKKDLEGPEGRFFHKNGYGSDKESDIWPPWIPLEMCFDGSLLDKHVFLKRRSMFLTYVAPNPLFFSANDTSAFSYDSRFRIAFPGLVLTSDCQQYCAVYAIAEDLLSFGSSLDEKVEKLSRILFTDEVRNNLENLDVSVVTALQERIKELYYTRAYLKLHEPRLFMKSGQELTFDIQTSTLKLTLLMTAIKKTYDRMGSGNRVIQKRLRWQVGTDELIWELYDESKTPFVTIGLGPSTFIRSETSDGTNSNKVSISSLQCFNQQENPVYTELLAPFYENSSYNKNAPMVEIFWILGPSVGGISDLQDLIVSLQPLIFKMDHKTSEKLMNYLFPKIEQTSIEPNSPELVPRSSTSSFFSSSPVLRHSLSNGSLSVYDAKDVDSWDLRSIQSKEGIKKHKGDHRKLSASLFVQPDYNINEMVKRSGTFFNVKSIIIRKTLMSVCYKGSHSLLTDVNNLIVRVPVLKYHNKLWSREEFFTALKRDVVRIVLQHLGNIIGNKFLPHKKENKKKTSMEIHRLLSPDSQNRDNSHILEVEGHNSFYSSTHSSDIRSINSDETYNENDGNGVKPFYPVTSEFSKNK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSMLPWSQI ------CCCCCHHHH | 40.09 | 30377154 | |
| 7 | Phosphorylation | -MSMLPWSQIRDVSK -CCCCCHHHHHHHHH | 17.50 | 30377154 | |
| 191 | N-linked_Glycosylation | PETKDTLNHTGFFMV CCCCCCCCCCEEEEE | 32.54 | - | |
| 210 | N-linked_Glycosylation | KEDDTGSNCTKVILK CCCCCCCCCHHHHHH | 38.53 | - | |
| 249 | Phosphorylation | SEPVEPFSAGDDAEM CCCCCCCCCCCCHHH | 41.90 | 28889911 | |
| 258 | Phosphorylation | GDDAEMLTSYRKMLK CCCHHHHHHHHHHHC | 23.54 | 28889911 | |
| 259 | Phosphorylation | DDAEMLTSYRKMLKP CCHHHHHHHHHHHCC | 20.98 | 28889911 | |
| 311 | N-linked_Glycosylation | ESISILNNVSALELL HHHHHHCCCCHHHHC | 26.19 | - | |
| 452 | N-linked_Glycosylation | LHISDEENVTFKVFS CCCCCCCCCEEEEEE | 35.76 | - | |
| 468 | N-linked_Glycosylation | HALFSRNNLSMTPKK CEEEECCCCCCCCCC | 32.17 | - | |
| 510 | Phosphorylation | IVGTSLSYLRIPTEQ EEECCHHHCCCCCCC | 12.80 | 27017623 | |
| 548 | Phosphorylation | NSKLIVQSTLRHSYV CCEEEEECCCCCCEE | 20.65 | 28889911 | |
| 565 | Phosphorylation | ENIEVLHTLSRAFDK HHHHHHHHHHHHHHH | 23.44 | 28889911 | |
| 567 | Phosphorylation | IEVLHTLSRAFDKIY HHHHHHHHHHHHHHH | 23.79 | 28889911 | |
| 605 | N-linked_Glycosylation | NEAKKTFNWSLKLRM HHHHHHHCEEHHHHH | 32.43 | - | |
| 638 | N-linked_Glycosylation | PVEAENFNLSDVTRG HHHCCCCCHHHCCCC | 50.66 | - | |
| 663 | N-linked_Glycosylation | LADSQEKNFTIIDAS ECCCCCCCEEEEEEE | 38.24 | - | |
| 698 | N-linked_Glycosylation | TNLLLSFNDSDEIHF ECCHHHCCCCCCCEE | 44.49 | - | |
| 789 | N-linked_Glycosylation | GLSSSTKNLTIASLS CCCCCCCCCCHHHHH | 42.37 | - | |
| 835 | N-linked_Glycosylation | CKKSAVINTSLIHFH EEHHCEEECCEEEEE | 19.60 | - | |
| 951 | Phosphorylation | NVRLRSLYDTSRGQS HHHHHHHHCCCCCCC | 20.58 | 28889911 | |
| 981 | N-linked_Glycosylation | AYLRLLENFSTSWIA HHHHHHHHCCHHHHH | 35.82 | - | |
| 1255 | N-linked_Glycosylation | GTTIYVHNSTDPKEF CEEEEEECCCCHHHH | 36.24 | - | |
| 1404 | N-linked_Glycosylation | LFTDVLQNKTKFGRS CHHHHHHCCCCCCHH | 50.21 | - | |
| 1446 | Phosphorylation | LEKDRKITFTGLKGR CCCCCEEEEEEECCC | 20.41 | 28889911 | |
| 1476 | N-linked_Glycosylation | THTNQKLNKSKPVWK CHHCCCCCCCCCEEE | 54.30 | - | |
| 1527 | Phosphorylation | GILEDEPSRPITPQD CCCCCCCCCCCCHHH | 48.95 | 28889911 | |
| 1531 | Phosphorylation | DEPSRPITPQDVEYL CCCCCCCCHHHHHHH | 19.99 | 28889911 | |
| 1721 | Phosphorylation | ISLLRTNTVESFVSM HHHHHCCCHHHHHHC | 25.66 | 25752575 | |
| 1732 | Phosphorylation | FVSMRKASTMQVEST HHHCHHCCCCEEEEE | 27.70 | 24930733 | |
| 1733 | Phosphorylation | VSMRKASTMQVESTY HHCHHCCCCEEEEEC | 19.24 | 24930733 | |
| 1739 | Phosphorylation | STMQVESTYDNRFMV CCCEEEEECCCCEEE | 22.76 | 24930733 | |
| 1978 | N-linked_Glycosylation | NPLFFSANDTSAFSY CCEEECCCCCCCCCC | 52.47 | - | |
| 2035 | Phosphorylation | KLSRILFTDEVRNNL HHHHHHCCHHHHHHH | 28.01 | 19779198 | |
| 2189 | N-linked_Glycosylation | LLAPFYENSSYNKNA HHHHHCCCCCCCCCC | 25.52 | - | |
| 2254 | Phosphorylation | QTSIEPNSPELVPRS CCCCCCCCCCCCCCC | 30.39 | 23749301 | |
| 2261 | Phosphorylation | SPELVPRSSTSSFFS CCCCCCCCCCCCCCC | 31.72 | 28889911 | |
| 2276 | Phosphorylation | SSPVLRHSLSNGSLS CCCCCCCCCCCCCEE | 27.36 | 22369663 | |
| 2278 | Phosphorylation | PVLRHSLSNGSLSVY CCCCCCCCCCCEEEE | 42.00 | 22369663 | |
| 2279 | N-linked_Glycosylation | VLRHSLSNGSLSVYD CCCCCCCCCCEEEEE | 49.74 | - | |
| 2281 | Phosphorylation | RHSLSNGSLSVYDAK CCCCCCCCEEEEECC | 23.01 | 22369663 | |
| 2283 | Phosphorylation | SLSNGSLSVYDAKDV CCCCCCEEEEECCCC | 21.96 | 22369663 | |
| 2285 | Phosphorylation | SNGSLSVYDAKDVDS CCCCEEEEECCCCCC | 13.55 | 22369663 | |
| 2292 | Phosphorylation | YDAKDVDSWDLRSIQ EECCCCCCCCCCHHC | 23.49 | 28889911 | |
| 2297 | Phosphorylation | VDSWDLRSIQSKEGI CCCCCCCHHCCHHCH | 32.07 | 24961812 | |
| 2358 | Phosphorylation | VCYKGSHSLLTDVNN HHHCCCCHHHCCCCH | 27.11 | 19779198 | |
| 2361 | Phosphorylation | KGSHSLLTDVNNLIV CCCCHHHCCCCHHHE | 43.10 | 19779198 | |
| 2432 | Phosphorylation | HRLLSPDSQNRDNSH HHHHCCCCCCCCCCC | 32.51 | 27214570 | |
| 2463 | Phosphorylation | SDIRSINSDETYNEN CCCCCCCCCCCCCCC | 34.84 | 23749301 | |
| 2466 | Phosphorylation | RSINSDETYNENDGN CCCCCCCCCCCCCCC | 36.32 | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YP117_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YP117_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YP117_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1721; SER-2254 ANDSER-2261, AND MASS SPECTROMETRY. | |
