PSD2_YEAST - dbPTM
PSD2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PSD2_YEAST
UniProt AC P53037
Protein Name Phosphatidylserine decarboxylase proenzyme 2 {ECO:0000255|HAMAP-Rule:MF_03209, ECO:0000305|PubMed:7890740}
Gene Name PSD2 {ECO:0000255|HAMAP-Rule:MF_03209, ECO:0000303|PubMed:7890739}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1138
Subcellular Localization Golgi apparatus membrane
Peripheral membrane protein
Cytoplasmic side . Endosome membrane
Peripheral membrane protein
Cytoplasmic side .
Protein Description Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. [PubMed: 7890740]
Protein Sequence MRIIKGRKRGKNKKPTLILKIHVIQAENIEALKTFNCNPVCFVTTNTFYSQKTNKLKNSNTHWNQTLRIKLPRNPTSEWLRIIVYDALPTGAPPTTPSRPRTTTANTSSSTLSNSGLSSHSHSSRNLNVTSKGNQTSTSINSVSSSATPAPSHSSSSLSTTGPGSTHKNRINSYLYLGEAKISLLDLFKRKDTTTSYKFSIEAQRYHLYDMKGGKDQDSLNCNFLVGDILLGFKLECNVKRTPTFQAFNAWRNELNTYLGRIDRNKARMRSSSSLPPPLEDMLSNSSAVSGNEIRREKPYSDTDLAHDEEVNAEDEIDAEESIEDMNSSGSICTERRYDIDNDTIFDSISEVVSLNDEELDILNDFEEADHPNVPDINVHDIDEDTRISLSSMITALDEYDIVEPEDVAKLPAVSENDITSVDDEESENQQESDEEFDIYNEDEREDSDFQSKEYIGSRLLHLQRGKHNKSYANYLYRRAKSNFFISKKEHAMGVVFMHIGAIKNLPALRNRLSKTNYEMDPFIVISFGRRVFKTSWRKHTLNPEFNEYAAFEVFPHETNFAFSIKVVDKDSFSFNDDVAKCELAWFDMLQQQQHENEWIPYEIPLDLTVEPAHAPKQPVLYSSFKYVSYPFLKKSFWKEAVDTSVNLERLDIIQVMLYLERLGSFTMADSFELFQHFNKSAWAGQSITRSQLVEGLQSWRKSTNFKRIWTCPRCMRSCKPTRNARRSKLVLENDLITHFAICTFSKEHKTLKPSYVSSAFASKRWFSKVLIKLTYGKYALGSNNANILVQDRDTGIIIEEKISAHVKLGMRIIYNGKSPESKKFRSLLKTLSIRQGKKFDSTASAKQIEPFIKFHSLDLSQCRDKDFKTFNEFFYRKLKPGSRLPESNNKEILFSPADSRCTVFPTIQESKEIWVKGRKFSIKKLANNYNPETFNDNNCSIGIFRLAPQDYHRFHSPCNGTIGKPVYVDGEYYTVNPMAVRSELDVFGENIRVIIPIDSPQFGKLLYIPIGAMMVGSILLTCKENDVVESGQELGYFKFGGSTIIIIIPHNNFMFDSDLVKNSSERIETLVKVGMSIGHTSNVNELKRIRIKVDDPKKIERIKRTISVSDENAKSTGNVTWEYHTLREMMNKDFAGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
85PhosphorylationEWLRIIVYDALPTGA
CCEEEEEEECCCCCC		5.7727017623
95PhosphorylationLPTGAPPTTPSRPRT
CCCCCCCCCCCCCCC		50.7227017623
98PhosphorylationGAPPTTPSRPRTTTA
CCCCCCCCCCCCCCC		53.4727017623
102PhosphorylationTTPSRPRTTTANTSS
CCCCCCCCCCCCCCC		31.0522369663
103PhosphorylationTPSRPRTTTANTSSS
CCCCCCCCCCCCCCC		25.7822369663
104PhosphorylationPSRPRTTTANTSSST
CCCCCCCCCCCCCCC		19.8022369663
107PhosphorylationPRTTTANTSSSTLSN
CCCCCCCCCCCCCCC		27.7622369663
108PhosphorylationRTTTANTSSSTLSNS
CCCCCCCCCCCCCCC		23.3022369663
109PhosphorylationTTTANTSSSTLSNSG
CCCCCCCCCCCCCCC		25.8822369663
110PhosphorylationTTANTSSSTLSNSGL
CCCCCCCCCCCCCCC		32.8922369663
111PhosphorylationTANTSSSTLSNSGLS
CCCCCCCCCCCCCCC		35.8322369663
113PhosphorylationNTSSSTLSNSGLSSH
CCCCCCCCCCCCCCC		29.1022369663
115PhosphorylationSSSTLSNSGLSSHSH
CCCCCCCCCCCCCCC		37.4222369663
118PhosphorylationTLSNSGLSSHSHSSR
CCCCCCCCCCCCCCC		29.5422369663
119PhosphorylationLSNSGLSSHSHSSRN
CCCCCCCCCCCCCCC		33.7722369663
121PhosphorylationNSGLSSHSHSSRNLN
CCCCCCCCCCCCCCE		27.3222369663
123PhosphorylationGLSSHSHSSRNLNVT
CCCCCCCCCCCCEEC		33.7323749301
124PhosphorylationLSSHSHSSRNLNVTS
CCCCCCCCCCCEECC		21.5522369663
136PhosphorylationVTSKGNQTSTSINSV
ECCCCCCCCCEEEEE		37.6623749301
139PhosphorylationKGNQTSTSINSVSSS
CCCCCCCEEEEECCC		21.3821551504
142PhosphorylationQTSTSINSVSSSATP
CCCCEEEEECCCCCC		23.0023749301
144PhosphorylationSTSINSVSSSATPAP
CCEEEEECCCCCCCC		20.5621551504
157PhosphorylationAPSHSSSSLSTTGPG
CCCCCCCCCCCCCCC		28.4321440633
286PhosphorylationLEDMLSNSSAVSGNE
HHHHHCCCCCCCCCC		19.1223749301
290PhosphorylationLSNSSAVSGNEIRRE
HCCCCCCCCCCCCCC		35.3023749301
471PhosphorylationQRGKHNKSYANYLYR
HCCCCCHHHHHHHHH		34.4922369663
516PhosphorylationLRNRLSKTNYEMDPF
HHHHHHHCCCCCCCE		39.3928889911
518PhosphorylationNRLSKTNYEMDPFIV
HHHHHCCCCCCCEEE		20.1928889911
738PhosphorylationVLENDLITHFAICTF
EEECCHHHEEEEEEC		20.4523749301
744PhosphorylationITHFAICTFSKEHKT
HHEEEEEECCCCCCC		25.4923749301
753UbiquitinationSKEHKTLKPSYVSSA
CCCCCCCCHHHHCHH		36.8322106047
857PhosphorylationEPFIKFHSLDLSQCR
HHHEEEECCCHHHHC		27.0628889911
1043PyruvateGYFKFGGSTIIIIIP
EEEEECCEEEEEEEE		19.47-
1043Pyruvic acid (Ser)GYFKFGGSTIIIIIP
EEEEECCEEEEEEEE		19.47-
1106PhosphorylationKIERIKRTISVSDEN
HHHHHEEEEECCCCC		16.7728152593
1108PhosphorylationERIKRTISVSDENAK
HHHEEEEECCCCCHH		18.2419823750
1110PhosphorylationIKRTISVSDENAKST
HEEEEECCCCCHHCC		32.2021440633
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PSD2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PSD2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PSD2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YRA1_YEASTYRA1physical
16554755
PDR17_YEASTPDR17physical
16554755
ICE2_YEASTICE2genetic
16269340
GET2_YEASTGET2genetic
16269340
PMT4_YEASTPMT4genetic
16269340
SCS7_YEASTSCS7genetic
16269340
PCY1_YEASTPCT1genetic
16269340
RGP1_YEASTRGP1genetic
16269340
PMT6_YEASTPMT6genetic
16269340
ILM1_YEASTILM1genetic
16269340
COPE_YEASTSEC28genetic
16269340
BRE5_YEASTBRE5genetic
16269340
OXA1_YEASTOXA1genetic
17976194
DCP1_YEASTDCP1genetic
17878665
ALE1_YEASTALE1genetic
20044027
AVT5_YEASTAVT5genetic
20093466
SNT1_YEASTSNT1genetic
20093466
CMR1_YEASTCMR1genetic
20093466
PHO2_YEASTPHO2genetic
20093466
BRE1_YEASTBRE1genetic
20093466
PP2C1_YEASTPTC1genetic
20093466
RPA14_YEASTRPA14genetic
20093466
DIT1_YEASTDIT1genetic
20093466
DOT1_YEASTDOT1genetic
20093466
GNP1_YEASTGNP1genetic
20093466
GET2_YEASTGET2genetic
20093466
RL22B_YEASTRPL22Bgenetic
20093466
MED5_YEASTNUT1genetic
20093466
YGK1_YEASTYGL101Wgenetic
20093466
ERV14_YEASTERV14genetic
20093466
GET1_YEASTGET1genetic
20093466
PACC_YEASTRIM101genetic
20093466
ICE2_YEASTICE2genetic
20093466
IF4A_YEASTTIF2genetic
20093466
DPOD3_YEASTPOL32genetic
20093466
LHS1_YEASTLHS1genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
VPS51_YEASTVPS51genetic
20093466
SIS2_YEASTSIS2genetic
20093466
BAS1_YEASTBAS1genetic
20093466
CSF1_YEASTCSF1genetic
20093466
SST2_YEASTSST2genetic
20093466
PHO84_YEASTPHO84genetic
20093466
CTK3_YEASTCTK3genetic
20093466
NU188_YEASTNUP188genetic
20093466
INP1_YEASTINP1genetic
20093466
SCS7_YEASTSCS7genetic
20093466
NST1_YEASTNST1genetic
20093466
MAS5_YEASTYDJ1genetic
20093466
HMI1_YEASTHMI1genetic
20093466
YP260_YEASTYPL260Wgenetic
20093466
MRX11_YEASTYPL041Cgenetic
20093466
CHMU_YEASTARO7genetic
20093466
CAJ1_YEASTCAJ1genetic
19325107
CWH41_YEASTCWH41genetic
19325107
CYS3_YEASTCYS3genetic
19325107
GET1_YEASTGET1genetic
19325107
VPS27_YEASTVPS27genetic
19325107
VPS52_YEASTVPS52genetic
19325107
VPS53_YEASTVPS53genetic
19325107
VPS54_YEASTVPS54genetic
19325107
ERG2_YEASTERG2genetic
21623372
ERG6_YEASTERG6genetic
21623372
CSG2_YEASTCSG2genetic
21623372
ADH3_YEASTADH3genetic
21623372
SGPL_YEASTDPL1genetic
21825164
PSD1_YEASTPSD1genetic
22409400
MDM10_YEASTMDM10genetic
22409400
MDM34_YEASTMDM34genetic
22409400
UPS1_YEASTUPS1genetic
22403410
PSD1_YEASTPSD1genetic
12441642
MET30_YEASTMET30genetic
12393893
MTC4_YEASTMTC4genetic
23891562
GPI11_YEASTGPI11genetic
23891562
SAC7_YEASTSAC7genetic
23891562
HAC1_YEASTHAC1genetic
23891562
IRE1_YEASTIRE1genetic
23891562
PLMT_YEASTOPI3genetic
23891562
AAKG_YEASTSNF4genetic
23891562
PSD1_YEASTPSD1genetic
23891562
GET2_YEASTGET2genetic
23891562
GLO3_YEASTGLO3genetic
23891562
ERV14_YEASTERV14genetic
23891562
TRS20_YEASTTRS20genetic
23891562
RGP1_YEASTRGP1genetic
23891562
RIC1_YEASTRIC1genetic
23891562
SRO7_YEASTSRO7genetic
23891562
CSG2_YEASTCSG2genetic
23891562
SNC2_YEASTSNC2genetic
23891562
ICE2_YEASTICE2genetic
23891562
PDR17_YEASTPDR17physical
24366873
STE50_YEASTSTE50genetic
27708008
YBQ6_YEASTYBR056Wgenetic
27708008
ECM8_YEASTECM8genetic
27708008
VAC17_YEASTVAC17genetic
27708008
NHP10_YEASTNHP10genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
BRE1_YEASTBRE1genetic
27708008
PHO2_YEASTPHO2genetic
27708008
CMR1_YEASTCMR1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
SWF1_YEASTSWF1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
UME6_YEASTUME6genetic
27708008
GGA1_YEASTGGA1genetic
27708008
DIT1_YEASTDIT1genetic
27708008
GNP1_YEASTGNP1genetic
27708008
GET2_YEASTGET2genetic
27708008
ODPA_YEASTPDA1genetic
27708008
ERV14_YEASTERV14genetic
27708008
YGK1_YEASTYGL101Wgenetic
27708008
MED5_YEASTNUT1genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
RS27B_YEASTRPS27Bgenetic
27708008
MED20_YEASTSRB2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
ICE2_YEASTICE2genetic
27708008
IF4A_YEASTTIF2genetic
27708008
SHE2_YEASTSHE2genetic
27708008
IRS4_YEASTIRS4genetic
27708008
VPS51_YEASTVPS51genetic
27708008
SIS2_YEASTSIS2genetic
27708008
BAS1_YEASTBAS1genetic
27708008
CSF1_YEASTCSF1genetic
27708008
CTK3_YEASTCTK3genetic
27708008
PHO84_YEASTPHO84genetic
27708008
INP1_YEASTINP1genetic
27708008
SCS7_YEASTSCS7genetic
27708008
NST1_YEASTNST1genetic
27708008
SFL1_YEASTSFL1genetic
27708008
MRX11_YEASTYPL041Cgenetic
27708008
SUR1_YEASTSUR1genetic
27708008
MGR2_YEASTMGR2genetic
27708008
MED1_YEASTMED1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PSD2_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1108, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory