dbPTM

INP1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	INP1_YEAST
UniProt AC	Q03694
Protein Name	Inheritance of peroxisomes protein 1
Gene Name	INP1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	420
Subcellular Localization	Peroxisome membrane Peripheral membrane protein .
Protein Description	Required for peroxisome inheritance..
Protein Sequence	MVLSRGETKKNSVRLTAKQEKKPQSTFQTLKQSLKLSNNKKLKQDSTQHSNDTNKSVKAKKNGTSSKKTGTQRKRISTQRFSLFTYGNVQVMNSFVPIHNDIPNSSCIRRNSQVSANNVTESSGVFFNDTQSQDSQNTIKLKPTSLMAKGPIEIYQICTGFDKLKENIAPFQKSSKASSHDGHVVNYLSIGRHGDIVHPVLPKLQITRLNGAGFKYFISFYNPERYWEIEFLPLISQSQSELENSVKAFENVISKICQFSHINEGATIGNNESLSDKFKLPPTSDIEPPNTEIINNDDDNDDDDDNYDDDDLNYLLDEEYEQGCTDNSFSVISNTCSNLNASFLYPSDPTDAVSISINEAFKNAIRRTAPVLNIPIAAPSIHSKQQNKRYSSYPFIDSPPYLQDRHRRFQRRSISGLGDL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
112	Phosphorylation	SSCIRRNSQVSANNV CHHHCCCCCCCCCCC	30.10	27214570
115	Phosphorylation	IRRNSQVSANNVTES HCCCCCCCCCCCCCC	20.03	28889911
174	Phosphorylation	NIAPFQKSSKASSHD HCCCCCCCCCCCCCC	26.70	24961812
175	Phosphorylation	IAPFQKSSKASSHDG CCCCCCCCCCCCCCC	39.00	24961812
273	Phosphorylation	ATIGNNESLSDKFKL CCCCCCCCHHHCCCC	34.98	20377248
275	Phosphorylation	IGNNESLSDKFKLPP CCCCCCHHHCCCCCC	48.29	21551504
391	Phosphorylation	KQQNKRYSSYPFIDS CCCCCCCCCCCCCCC	27.68	27214570
398	Phosphorylation	SSYPFIDSPPYLQDR CCCCCCCCCCCHHHH	23.98	27214570
413	Phosphorylation	HRRFQRRSISGLGDL HHHHHHHCCCCCCCC	24.24	28889911
415	Phosphorylation	RFQRRSISGLGDL-- HHHHHCCCCCCCC--	29.25	15665377

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of INP1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of INP1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of INP1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PEX25_YEAST	PEX25	physical	15928207
PEX30_YEAST	PEX30	physical	15928207
VPS1_YEAST	VPS1	physical	15928207
ATG36_YEAST	ATG36	physical	11283351
PEX3_YEAST	PEX3	physical	19948495
PEX3_YEAST	PEX3	physical	23900285
SHE1_YEAST	SHE1	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
YIA6_YEAST	YIA6	genetic	27708008
YRA2_YEAST	YRA2	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
VAM3_YEAST	VAM3	genetic	27708008
MNN2_YEAST	MNN2	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
BRE1_YEAST	BRE1	genetic	27708008
ARO1_YEAST	ARO1	genetic	27708008
RTG2_YEAST	RTG2	genetic	27708008
VMA21_YEAST	VMA21	genetic	27708008
YIC9_YEAST	YIL029C	genetic	27708008
YIF4_YEAST	YIL054W	genetic	27708008
ECM25_YEAST	ECM25	genetic	27708008
RL14A_YEAST	RPL14A	genetic	27708008
DBR1_YEAST	DBR1	genetic	27708008
EI2BA_YEAST	GCN3	genetic	27708008
RS30A_YEAST	RPS30A	genetic	27708008
RS30B_YEAST	RPS30A	genetic	27708008
MDM30_YEAST	MDM30	genetic	27708008
ATP10_YEAST	ATP10	genetic	27708008
USA1_YEAST	USA1	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
BEM4_YEAST	BEM4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of INP1_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-273, AND MASSSPECTROMETRY.	17330950 [Abstract]
"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-415, AND MASSSPECTROMETRY.	15665377 [Abstract]