dbPTM

HUT1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HUT1_YEAST
UniProt AC	Q12520
Protein Name	UDP-galactose transporter homolog 1
Gene Name	HUT1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	339
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description	May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum. Overexpression confers resistance to the immunosuppressive drug, leflunomide..
Protein Sequence	MAGSTSSLVICAIGIYATFLTWALVQEPLATRTWPNSMGKFQFPNVISLIQASVAMMMGYLYLNWKKVEYPPRKMIKDHWKQLMLISFTQSSSGPLATTSLKHVDYLTYMLAKSCKMIPVLLVHLLLYRTPIASQKKVVALLVSLGVTIFTIGGNDGKKLKRSFNESGNDNKLQGFGLLFSSLFLDGLTNATQDKLLKANKAKEKGKQTLITGAHLMFTLNLFVILWNILYFIVIDCKQWDNAVSVLTMDPQVWGYLMLYSFCGAMGQCFIFYTLEQFGSLVLIMITVTRKMVSMILSIIVFGKSVRFQQWVGMFIVFGGITWEALNKKKANIPKAKSA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
165	N-linked_Glycosylation	KKLKRSFNESGNDNK HHHHHHHCCCCCCCC	43.71	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HUT1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HUT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HUT1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATS1_YEAST	ATS1	genetic	20093466
SEC66_YEAST	SEC66	genetic	20093466
SSH1_YEAST	SSH1	genetic	20093466
GET3_YEAST	GET3	genetic	20093466
PMP3_YEAST	PMP3	genetic	20093466
GET2_YEAST	GET2	genetic	20093466
GET1_YEAST	GET1	genetic	20093466
PLMT_YEAST	OPI3	genetic	20093466
LHS1_YEAST	LHS1	genetic	20093466
ENV10_YEAST	ENV10	genetic	20093466
MSB4_YEAST	MSB4	genetic	20093466
ISW2_YEAST	ISW2	genetic	20093466
SEC66_YEAST	SEC66	genetic	27708008
SSH1_YEAST	SSH1	genetic	27708008
GET3_YEAST	GET3	genetic	27708008
GET2_YEAST	GET2	genetic	27708008
YER4_YEAST	YER084W	genetic	27708008
GET1_YEAST	GET1	genetic	27708008
ASK10_YEAST	ASK10	genetic	27708008
LHS1_YEAST	LHS1	genetic	27708008
UBR2_YEAST	UBR2	genetic	27708008
ENV10_YEAST	ENV10	genetic	27708008
UBA3_YEAST	UBA3	genetic	27708008
GET2_YEAST	GET2	genetic	29674565
GET1_YEAST	GET1	genetic	29674565
TIP20_YEAST	TIP20	genetic	29674565
ICE2_YEAST	ICE2	genetic	29674565
SEC23_YEAST	SEC23	genetic	29674565
CSG2_YEAST	CSG2	genetic	29674565
GET3_YEAST	GET3	genetic	29674565
CDC1_YEAST	CDC1	genetic	29674565
TFB1_YEAST	TFB1	genetic	29674565
PPN1_YEAST	PPN1	genetic	29674565
ATC1_YEAST	PMR1	genetic	29674565
RS21B_YEAST	RPS21B	genetic	29674565
YJ9I_YEAST	YJR141W	genetic	29674565
RL14A_YEAST	RPL14A	genetic	29674565
VPS24_YEAST	VPS24	genetic	29674565
ELM1_YEAST	ELM1	genetic	29674565
FABG_YEAST	OAR1	genetic	29674565
KTI12_YEAST	KTI12	genetic	29674565
PRS7_YEAST	RPT1	genetic	29674565
LST4_YEAST	LST4	genetic	29674565
SAC1_YEAST	SAC1	genetic	29674565
VPS51_YEAST	VPS51	genetic	29674565
RS21A_YEAST	RPS21A	genetic	29674565
BET3_YEAST	BET3	genetic	29674565
CSF1_YEAST	CSF1	genetic	29674565
OST1_YEAST	OST1	genetic	29674565

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HUT1_YEAST

Related Literatures of Post-Translational Modification