GPI18_YEAST - dbPTM
GPI18_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GPI18_YEAST
UniProt AC P38211
Protein Name GPI mannosyltransferase 2
Gene Name GPI18
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 433
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly..
Protein Sequence MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPSEINSYWNKYFWNKLLSWDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNNDSIYHALRVGVAIENVLFYLSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSAAGFLTSIYSEPLSFFFAFVGIWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLASLNRSNCVLLGIYFIFDLIELTKNRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCPQRGEWCKSQLFSSIFITKTSLYSYIQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIYSSIYFSKIYPSYNLKALVWITRALVVIVCFFAHVQILNRIASFLPLHLWYLADRLVKTSDPKKMENPKGDDKIVKFYIYWLAFWIPLQTILFAAFLPPA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
69N-linked_GlycosylationDSVFFIKNITSKNGK
CEEEEEEECCCCCCC		37.64-
101N-linked_GlycosylationRLFIKSNNDSIYHAL
HHHHHCCCCHHHHHH		52.04-
135PhosphorylationFLTKKIFSQNIRQSQ
HHHHHHHCCCCCHHH		26.2823607784
202PhosphorylationQFDISWRYWFPYSFI
CCEEEEECCCCHHHH		12.7319779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GPI18_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GPI18_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GPI18_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PGA1_YEASTPGA1genetic
17615295
EMC5_YEASTEMC5physical
18467557
EMC5_YEASTEMC5physical
22615397
HAC1_YEASTHAC1genetic
23891562
IRE1_YEASTIRE1genetic
23891562
PLMT_YEASTOPI3genetic
23891562
GET2_YEASTGET2genetic
23891562
CANB_YEASTCNB1genetic
23891562
SGF29_YEASTSGF29genetic
27708008
COPA_YEASTCOP1genetic
27708008
UPPS_YEASTNUS1genetic
27708008
SLU7_YEASTSLU7genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
RPB7_YEASTRPB7genetic
27708008
GPI17_YEASTGPI17genetic
27708008
GPI19_YEASTGPI19genetic
27708008
PANK_YEASTCAB1genetic
27708008
COG3_YEASTCOG3genetic
27708008
ACT_YEASTACT1genetic
27708008
PMM_YEASTSEC53genetic
27708008
STT3_YEASTSTT3genetic
27708008
GPI10_YEASTGPI10genetic
27708008
SWC4_YEASTSWC4genetic
27708008
GPI16_YEASTGPI16genetic
27708008
PAN1_YEASTPAN1genetic
27708008
GRP78_YEASTKAR2genetic
27708008
GWT1_YEASTGWT1genetic
27708008
BET3_YEASTBET3genetic
27708008
GPI13_YEASTGPI13genetic
27708008
PRP19_YEASTPRP19genetic
27708008
SED5_YEASTSED5genetic
27708008
SPC3_YEASTSPC3genetic
27708008
GAA1_YEASTGAA1genetic
27708008
ERG27_YEASTERG27genetic
27708008
SC61A_YEASTSEC61genetic
27708008
CDC91_YEASTGAB1genetic
27708008
ERO1_YEASTERO1genetic
27708008
SEC59_YEASTSEC59genetic
27708008
ROT1_YEASTROT1genetic
27708008
RNA1_YEASTRNA1genetic
27708008
GPI15_YEASTGPI15genetic
27708008
DPOA_YEASTPOL1genetic
27708008
TYSY_YEASTCDC21genetic
27708008
SMP3_YEASTSMP3genetic
27708008
DYR_YEASTDFR1genetic
27708008
KRE5_YEASTKRE5genetic
27708008
GPI2_YEASTGPI2genetic
27708008
DPM1_YEASTDPM1genetic
27708008
LTE1_YEASTLTE1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
CWH43_YEASTCWH43genetic
27708008
MDHP_YEASTMDH3genetic
27708008
MAF1_YEASTMAF1genetic
27708008
UME6_YEASTUME6genetic
27708008
MNN10_YEASTMNN10genetic
27708008
SAC7_YEASTSAC7genetic
27708008
HEH2_YEASTHEH2genetic
27708008
MAG_YEASTMAG1genetic
27708008
ICE2_YEASTICE2genetic
27708008
GPI7_YEASTLAS21genetic
27708008
LHS1_YEASTLHS1genetic
27708008
NU133_YEASTNUP133genetic
27708008
CSF1_YEASTCSF1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
ARV1_YEASTARV1genetic
27708008
NU188_YEASTNUP188genetic
27708008
ATP23_YEASTATP23genetic
27708008
ALG6_YEASTALG6genetic
27708008
ALG8_YEASTALG8genetic
27708008
OST3_YEASTOST3genetic
27708008
RUD3_YEASTRUD3genetic
27708008
ENV9_YEASTENV9genetic
27708008
NACB1_YEASTEGD1genetic
27708008
LGE1_YEASTLGE1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GPI18_YEAST

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Related Literatures of Post-Translational Modification

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