PGA1_YEAST - dbPTM
PGA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PGA1_YEAST
UniProt AC P53896
Protein Name GPI mannosyltransferase 2 subunit PGA1
Gene Name PGA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 198
Subcellular Localization Endoplasmic reticulum membrane
Single-pass membrane protein .
Protein Description Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly..
Protein Sequence MVRPQNVHWFIATIVFFIGFVHANTESILYKVPHNFPLKKPRDSSTYARDVNLISSISLSGEAMSQITIEANTTDLELHNTTYIELADLQRDETYQIKVCWSAIHPISINNLQTITIPRFTEFQGTKSDYARILVTFQVLSDSYPSEHAMVPIQVSLITTRLGIPVDIYPTLIVMVLLVAGLVVTRAPHVLNDLLLKF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
72N-linked_GlycosylationSQITIEANTTDLELH
HCEEEEECCCCEEEC
30.62-
80N-linked_GlycosylationTTDLELHNTTYIELA
CCCEEECCCEEEEEE
46.90-
127UbiquitinationFTEFQGTKSDYARIL
CCEECCCCHHHEEEE
48.4223749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PGA1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PGA1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PGA1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GPI18_YEASTGPI18genetic
17615295
APC11_YEASTAPC11genetic
27708008
CWC15_YEASTCWC15genetic
27708008
LSM1_YEASTLSM1genetic
27708008
GAP1_YEASTGAP1genetic
27708008
SWI6_YEASTSWI6genetic
27708008
LIPA_YEASTLIP5genetic
27708008
GPI18_YEASTGPI18genetic
27708008
IPYR_YEASTIPP1genetic
27708008
ALG14_YEASTALG14genetic
27708008
KRR1_YEASTKRR1genetic
27708008
TIM22_YEASTTIM22genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
GPI19_YEASTGPI19genetic
27708008
COG3_YEASTCOG3genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
GPI10_YEASTGPI10genetic
27708008
GPI16_YEASTGPI16genetic
27708008
ATC7_YEASTNEO1genetic
27708008
GWT1_YEASTGWT1genetic
27708008
SED5_YEASTSED5genetic
27708008
BOS1_YEASTBOS1genetic
27708008
ERG27_YEASTERG27genetic
27708008
CDC91_YEASTGAB1genetic
27708008
GPI12_YEASTGPI12genetic
27708008
SMP3_YEASTSMP3genetic
27708008
KRE5_YEASTKRE5genetic
27708008
GPI2_YEASTGPI2genetic
27708008
DPM1_YEASTDPM1genetic
27708008
ALG3_YEASTALG3genetic
27708008
RXT2_YEASTRXT2genetic
27708008
CCZ1_YEASTCCZ1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
NHP10_YEASTNHP10genetic
27708008
VAM6_YEASTVAM6genetic
27708008
OST4_YEASTOST4genetic
27708008
VPS41_YEASTVPS41genetic
27708008
NBP2_YEASTNBP2genetic
27708008
PEX10_YEASTPEX10genetic
27708008
RT103_YEASTRTT103genetic
27708008
HEH2_YEASTHEH2genetic
27708008
IES5_YEASTIES5genetic
27708008
RAD51_YEASTRAD51genetic
27708008
RAD4_YEASTRAD4genetic
27708008
RIM15_YEASTRIM15genetic
27708008
VAM7_YEASTVAM7genetic
27708008
SNG1_YEASTSNG1genetic
27708008
NPR3_YEASTNPR3genetic
27708008
IGO2_YEASTIGO2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
ICE2_YEASTICE2genetic
27708008
VPS53_YEASTVPS53genetic
27708008
GPI7_YEASTLAS21genetic
27708008
MDV1_YEASTMDV1genetic
27708008
YJ24_YEASTKCH1genetic
27708008
LHS1_YEASTLHS1genetic
27708008
LST4_YEASTLST4genetic
27708008
NU133_YEASTNUP133genetic
27708008
FPS1_YEASTFPS1genetic
27708008
ARP6_YEASTARP6genetic
27708008
CSF1_YEASTCSF1genetic
27708008
ARV1_YEASTARV1genetic
27708008
NUP2_YEASTNUP2genetic
27708008
ROM2_YEASTROM2genetic
27708008
NU188_YEASTNUP188genetic
27708008
PUR1_YEASTADE4genetic
27708008
GAS1_YEASTGAS1genetic
27708008
TLG2_YEASTTLG2genetic
27708008
NOP12_YEASTNOP12genetic
27708008
INO4_YEASTINO4genetic
27708008
ALG6_YEASTALG6genetic
27708008
BUB3_YEASTBUB3genetic
27708008
ALG8_YEASTALG8genetic
27708008
GYP1_YEASTGYP1genetic
27708008
OST3_YEASTOST3genetic
27708008
YO214_YEASTSPR2genetic
27708008
ENV9_YEASTENV9genetic
27708008
CAF20_YEASTCAF20genetic
27708008
PDE2_YEASTPDE2genetic
27708008
CARP_YEASTPEP4genetic
27708008
ALG5_YEASTALG5genetic
27708008
THP3_YEASTTHP3genetic
27708008
UBA3_YEASTUBA3genetic
27708008
SPEE_YEASTSPE3genetic
27708008
AXL1_YEASTAXL1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PGA1_YEAST

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Related Literatures of Post-Translational Modification

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