| UniProt ID | CARP_YEAST | |
|---|---|---|
| UniProt AC | P07267 | |
| Protein Name | Saccharopepsin | |
| Gene Name | PEP4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 405 | |
| Subcellular Localization | Vacuole. Lysosome-like vacuoles. | |
| Protein Description | Aspartyl protease implicated in the post-translational regulation of S.cerevisiae vacuolar proteinases. Acts on YSCB, on YSCY and on itself.. | |
| Protein Sequence | MFSLKALLPLALLLVSANQVAAKVHKAKIYKHELSDEMKEVTFEQHLAHLGQKYLTQFEKANPEVVFSREHPFFTEGGHDVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGSCISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKAI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 28 | Ubiquitination | AAKVHKAKIYKHELS HHHHHHHHHHHHCCC | 51.91 | 17644757 | |
| 31 | Ubiquitination | VHKAKIYKHELSDEM HHHHHHHHHCCCHHH | 33.79 | 17644757 | |
| 39 | Ubiquitination | HELSDEMKEVTFEQH HCCCHHHHHCHHHHH | 47.16 | 17644757 | |
| 53 | Ubiquitination | HLAHLGQKYLTQFEK HHHHHHHHHHHHHHH | 40.19 | 17644757 | |
| 60 | Ubiquitination | KYLTQFEKANPEVVF HHHHHHHHHCCCEEE | 55.54 | 23749301 | |
| 60 | Acetylation | KYLTQFEKANPEVVF HHHHHHHHHCCCEEE | 55.54 | 24489116 | |
| 133 | Phosphorylation | ACFLHSKYDHEASSS HHHHHHCCCCCCCCC | 26.08 | 27214570 | |
| 144 | N-linked_Glycosylation | ASSSYKANGTEFAIQ CCCCCEECCCEEEEE | 54.49 | - | |
| 226 | Acetylation | QQDLLDEKRFAFYLG HHHHHCCCCEEEEEC | 53.10 | 24489116 | |
| 256 | Acetylation | GIDESKFKGDITWLP CCCHHHCCCCEEEEE | 60.45 | 24489116 | |
| 317 | Ubiquitination | INAEIGAKKGWTGQY HHHHCCCCCCCCEEE | 46.75 | 17644757 | |
| 318 | Ubiquitination | NAEIGAKKGWTGQYT HHHCCCCCCCCEEEE | 60.18 | 23749301 | |
| 345 | N-linked_Glycosylation | IFNFNGYNFTIGPYD EEEECCEEEEECCCC | 29.05 | - | |
| 387 | Ubiquitination | VGDAFLRKYYSIYDL ECHHHHHHHCEEEEC | 51.17 | 23749301 | |
| 388 | Phosphorylation | GDAFLRKYYSIYDLG CHHHHHHHCEEEECC | 8.94 | 21440633 | |
| 403 | Acetylation | NNAVGLAKAI----- CCHHHHHHCC----- | 52.21 | 24489116 | |
| 403 | Ubiquitination | NNAVGLAKAI----- CCHHHHHHCC----- | 52.21 | 17644757 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CARP_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CARP_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
