dbPTM

FAR10_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FAR10_YEAST
UniProt AC	Q06001
Protein Name	Factor arrest protein 10
Gene Name	FAR10
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	478
Subcellular Localization	Membrane Single-pass type IV membrane protein .
Protein Description	Participates in the control of the reentry into the cell cycle following pheromone treatment..
Protein Sequence	MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGSTNSSKRPIEKYDKRIADPTKSYFPHSISRTPRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLGRPVANSNSSSSSSLRGGKRVDSHTFSQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYIRDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLESPIFENEDSDDCHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCIGTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVKLQNGLRRKLSGKYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVPGMNPKGTDKFSIKNTLCNHFTLLTFGTISIGIIAIVFKILSPN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	INKEEHPSSPGKKQI CCCCCCCCCCCCCCC	51.58	27717283
16	Phosphorylation	NKEEHPSSPGKKQIT CCCCCCCCCCCCCCE	41.97	29136822
72	Phosphorylation	SRTPRRKYTYILVLT CCCCCCCEEEEEEEE	11.72	30377154
73	Phosphorylation	RTPRRKYTYILVLTS CCCCCCEEEEEEEEE	13.71	30377154
74	Phosphorylation	TPRRKYTYILVLTSL CCCCCEEEEEEEEEC	6.81	30377154
79	Phosphorylation	YTYILVLTSLNGTFE EEEEEEEEECCCCEE	24.56	30377154
80	Phosphorylation	TYILVLTSLNGTFES EEEEEEEECCCCEEC	18.71	30377154
84	Phosphorylation	VLTSLNGTFESKHVV EEEECCCCEECCEEE	24.13	30377154
87	Phosphorylation	SLNGTFESKHVVIPF ECCCCEECCEEEEEE	24.70	30377154
108	Phosphorylation	LGRPVANSNSSSSSS CCCCCCCCCCCCCCC	28.49	22369663
110	Phosphorylation	RPVANSNSSSSSSLR CCCCCCCCCCCCCCC	31.27	22369663
111	Phosphorylation	PVANSNSSSSSSLRG CCCCCCCCCCCCCCC	38.19	22369663
112	Phosphorylation	VANSNSSSSSSLRGG CCCCCCCCCCCCCCC	33.78	22369663
113	Phosphorylation	ANSNSSSSSSLRGGK CCCCCCCCCCCCCCC	26.37	23749301
114	Phosphorylation	NSNSSSSSSLRGGKR CCCCCCCCCCCCCCC	35.03	21440633
115	Phosphorylation	SNSSSSSSLRGGKRV CCCCCCCCCCCCCCC	24.84	22369663
227	Phosphorylation	PIFENEDSDDCHTIT CCCCCCCCCCCCCCC	29.21	21440633
288	Phosphorylation	TLSNIIKTLAMEIPF CHHHHHHHHHHCCCH	14.89	28889911
419	Phosphorylation	KQKEQELSTASKKKT HHHHHHHHHHHCCCC	22.60	17287358
420	Phosphorylation	QKEQELSTASKKKTT HHHHHHHHHHCCCCC	47.80	17287358
422	Phosphorylation	EQELSTASKKKTTEH HHHHHHHHCCCCCCC	45.13	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FAR10_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FAR10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FAR10_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHO84_YEAST	PHO84	physical	11805837
FET4_YEAST	FET4	physical	11805837
FAR8_YEAST	FAR8	physical	11805837
VPS64_YEAST	VPS64	physical	10688190
STE50_YEAST	STE50	genetic	19269370
CAK1_YEAST	CAK1	genetic	19269370
APQ12_YEAST	APQ12	genetic	19269370
SEC22_YEAST	SEC22	genetic	19269370
TCO89_YEAST	TCO89	genetic	19269370
EAF3_YEAST	EAF3	genetic	19269370
FMT_YEAST	FMT1	genetic	20093466
RCR1_YEAST	RCR1	genetic	20093466
CSG2_YEAST	CSG2	genetic	20093466
FAT1_YEAST	FAT1	genetic	20093466
IML3_YEAST	IML3	genetic	20093466
TPS1_YEAST	TPS1	genetic	20093466
MBA1_YEAST	MBA1	genetic	20093466
PBP2_YEAST	PBP2	genetic	20093466
SSH1_YEAST	SSH1	genetic	20093466
RV161_YEAST	RVS161	genetic	20093466
HCM1_YEAST	HCM1	genetic	20093466
CSM1_YEAST	CSM1	genetic	20093466
KIN82_YEAST	KIN82	genetic	20093466
UGA3_YEAST	UGA3	genetic	20093466
PMT5_YEAST	PMT5	genetic	20093466
UBX3_YEAST	UBX3	genetic	20093466
RS16A_YEAST	RPS16B	genetic	20093466
RS16B_YEAST	RPS16B	genetic	20093466
MTU1_YEAST	SLM3	genetic	20093466
PP2C1_YEAST	PTC1	genetic	20093466
RM01_YEAST	MRPL1	genetic	20093466
STB3_YEAST	STB3	genetic	20093466
HSP42_YEAST	HSP42	genetic	20093466
CYPD_YEAST	CPR5	genetic	20093466
EAF1_YEAST	EAF1	genetic	20093466
SEM1_YEAST	SEM1	genetic	20093466
BCS1_YEAST	BCS1	genetic	20093466
RGI1_YEAST	RGI1	genetic	20093466
CHAC_YEAST	GCG1	genetic	20093466
RL29_YEAST	RPL29	genetic	20093466
MDS3_YEAST	MDS3	genetic	20093466
GUP1_YEAST	GUP1	genetic	20093466
YGI1_YEAST	YGL081W	genetic	20093466
PALF_YEAST	RIM8	genetic	20093466
ASK10_YEAST	ASK10	genetic	20093466
PCP1_YEAST	PCP1	genetic	20093466
YG3A_YEAST	YGR130C	genetic	20093466
PSA3_YEAST	PRE9	genetic	20093466
TPO2_YEAST	TPO2	genetic	20093466
CHO2_YEAST	CHO2	genetic	20093466
CBP4_YEAST	CBP4	genetic	20093466
DOG2_YEAST	DOG2	genetic	20093466
YIQ1_YEAST	YIL161W	genetic	20093466
FIS1_YEAST	FIS1	genetic	20093466
MGA2_YEAST	MGA2	genetic	20093466
ECM25_YEAST	ECM25	genetic	20093466
TOK1_YEAST	TOK1	genetic	20093466
YJE3_YEAST	YJL043W	genetic	20093466
PLMT_YEAST	OPI3	genetic	20093466
DHOM_YEAST	HOM6	genetic	20093466
TM184_YEAST	YKR051W	genetic	20093466
MMM1_YEAST	MMM1	genetic	20093466
VPS9_YEAST	VPS9	genetic	20093466
PRM6_YEAST	PRM6	genetic	20093466
AIM34_YEAST	AIM34	genetic	20093466
SAM37_YEAST	SAM37	genetic	20093466
SSO2_YEAST	SSO2	genetic	20093466
TGL3_YEAST	TGL3	genetic	20093466
CPT1_YEAST	CPT1	genetic	20093466
EOS1_YEAST	EOS1	genetic	20093466
ASI3_YEAST	ASI3	genetic	20093466
RCF2_YEAST	RCF2	genetic	20093466
YO114_YEAST	YOL114C	genetic	20093466
TLG2_YEAST	TLG2	genetic	20093466
MDM12_YEAST	MDM12	genetic	20093466
CY1_YEAST	CYT1	genetic	20093466
OST3_YEAST	OST3	genetic	20093466
SLP1_YEAST	SLP1	genetic	20093466
DGK1_YEAST	DGK1	genetic	20093466
SVL3_YEAST	SVL3	genetic	20093466
NAA30_YEAST	MAK3	genetic	20093466
MED1_YEAST	MED1	genetic	20093466
RFX1_YEAST	RFX1	genetic	21127252
ADA2_YEAST	ADA2	genetic	21127252
FAR11_YEAST	FAR11	physical	22298706
YAP6_YEAST	YAP6	physical	22875988
KIN82_YEAST	KIN82	genetic	22282571
YP084_YEAST	YPR084W	genetic	27708008
CDK1_YEAST	CDC28	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
USO1_YEAST	USO1	genetic	27708008
RPN6_YEAST	RPN6	genetic	27708008
RPN5_YEAST	RPN5	genetic	27708008
PANK_YEAST	CAB1	genetic	27708008
PSB3_YEAST	PUP3	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
PSB7_YEAST	PRE4	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
NUP57_YEAST	NUP57	genetic	27708008
RPN1_YEAST	RPN1	genetic	27708008
PRS7_YEAST	RPT1	genetic	27708008
GAA1_YEAST	GAA1	genetic	27708008
UTP15_YEAST	UTP15	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
PRS10_YEAST	RPT4	genetic	27708008
PSA7_YEAST	PRE10	genetic	27708008
RPN7_YEAST	RPN7	genetic	27708008
YAJ8_YEAST	YAR028W	genetic	27708008
RCR1_YEAST	RCR1	genetic	27708008
FAT1_YEAST	FAT1	genetic	27708008
YMC2_YEAST	YMC2	genetic	27708008
CCZ1_YEAST	CCZ1	genetic	27708008
REI1_YEAST	REI1	genetic	27708008
SSH1_YEAST	SSH1	genetic	27708008
AGP1_YEAST	AGP1	genetic	27708008
IMG2_YEAST	IMG2	genetic	27708008
CSM1_YEAST	CSM1	genetic	27708008
NHP10_YEAST	NHP10	genetic	27708008
PP2C1_YEAST	PTC1	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
MBP1_YEAST	MBP1	genetic	27708008
RS16A_YEAST	RPS16B	genetic	27708008
RS16B_YEAST	RPS16B	genetic	27708008
FADH_YEAST	SFA1	genetic	27708008
UGA3_YEAST	UGA3	genetic	27708008
STB3_YEAST	STB3	genetic	27708008
HSP42_YEAST	HSP42	genetic	27708008
SEM1_YEAST	SEM1	genetic	27708008
RLA4_YEAST	RPP2B	genetic	27708008
FTR1_YEAST	FTR1	genetic	27708008
RL29_YEAST	RPL29	genetic	27708008
MDS3_YEAST	MDS3	genetic	27708008
RTF1_YEAST	RTF1	genetic	27708008
KSS1_YEAST	KSS1	genetic	27708008
PFD3_YEAST	PAC10	genetic	27708008
YG3A_YEAST	YGR130C	genetic	27708008
PSA3_YEAST	PRE9	genetic	27708008
CHO2_YEAST	CHO2	genetic	27708008
CBP4_YEAST	CBP4	genetic	27708008
GOSR1_YEAST	GOS1	genetic	27708008
DOG2_YEAST	DOG2	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
YIF4_YEAST	YIL054W	genetic	27708008
FIS1_YEAST	FIS1	genetic	27708008
FLX1_YEAST	FLX1	genetic	27708008
MGA2_YEAST	MGA2	genetic	27708008
TOK1_YEAST	TOK1	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
DHOM_YEAST	HOM6	genetic	27708008
TM184_YEAST	YKR051W	genetic	27708008
MMM1_YEAST	MMM1	genetic	27708008
COX12_YEAST	COX12	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
LAM6_YEAST	YLR072W	genetic	27708008
UBX2_YEAST	UBX2	genetic	27708008
VPS9_YEAST	VPS9	genetic	27708008
CLU_YEAST	CLU1	genetic	27708008
SAM37_YEAST	SAM37	genetic	27708008
SSO2_YEAST	SSO2	genetic	27708008
ROY1_YEAST	ROY1	genetic	27708008
BUL1_YEAST	BUL1	genetic	27708008
TGL3_YEAST	TGL3	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
CPT1_YEAST	CPT1	genetic	27708008
RCF2_YEAST	RCF2	genetic	27708008
BRE5_YEAST	BRE5	genetic	27708008
TOP1_YEAST	TOP1	genetic	27708008
TLG2_YEAST	TLG2	genetic	27708008
YO114_YEAST	YOL114C	genetic	27708008
YO012_YEAST	YOR012W	genetic	27708008
BUB3_YEAST	BUB3	genetic	27708008
HIR2_YEAST	HIR2	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
DIA2_YEAST	DIA2	genetic	27708008
TCB1_YEAST	TCB1	genetic	27708008
PALA_YEAST	RIM20	genetic	27708008
DGK1_YEAST	DGK1	genetic	27708008
SVL3_YEAST	SVL3	genetic	27708008
LGE1_YEAST	LGE1	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
PTPA2_YEAST	RRD2	genetic	27708008
OYE3_YEAST	OYE3	genetic	27708008
NAA30_YEAST	MAK3	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FAR10_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-419 AND THR-420, ANDMASS SPECTROMETRY.	17287358 [Abstract]