TOK1_YEAST - dbPTM
TOK1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TOK1_YEAST
UniProt AC P40310
Protein Name Outward-rectifier potassium channel TOK1
Gene Name TOK1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 691
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description Outwardly rectifying potassium channel..
Protein Sequence MTRFMNSFAKQTLGYGNMATVEQESSAQAVDSHSNNTPKQAKGVLAEELKDALRFRDERVSIINAEPSSTLFVFWFVVSCYFPVITACLGPVANTISIACVVEKWRSLKNNSVVTNPRSNDTDVLMNQVKTVFDPPGIFAVNIISLVLGFTSNIILMLHFSKKLTYLKSQLINITGWTIAGGMLLVDVIVCSLNDMPSIYSKTIGFWFACISSGLYLVCTIILTIHFIGYKLGKYPPTFNLLPNERSIMAYTVLLSLWLIWGAGMFSGLLHITYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIFFFHRVEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTASRKQHWFSLSVTIAIFMAFWLLGALVFKFAENWSYFNCIYFCFLCLLTIGYGDYAPRTGAGRAFFVIWALGAVPLMGAILSTVGDLLFDISTSLDIKIGESFNNKVKSIVFNGRQRALSFMVNTGEIFEESDTADGDLEENTTSSQSSQISEFNDNNSEENDSGVTSPPASLQESFSSLSKASSPEGILPLEYVSSAEYALQDSGTCNLRNLQELLKAVKKLHRICLADKDYTLSFSDWSYIHKLHLRNITDIEEYTRGPEFWISPDTPLKFPLNEPHFAFMMLFKNIEELVGNLVEDEELYKVISKRKFLGEHRKTL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
119PhosphorylationSVVTNPRSNDTDVLM
CCCCCCCCCCHHHHH		40.0728889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TOK1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TOK1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TOK1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HOG1_YEASTHOG1physical
15294160
TRK1_YEASTTRK1genetic
10089235
TRK2_YEASTTRK2genetic
10089235
HAL1_YEASTHAL1genetic
9178503
SSH1_YEASTSSH1genetic
20093466
MAF1_YEASTMAF1genetic
20093466
RV167_YEASTRVS167genetic
20093466
STP1_YEASTSTP1genetic
20093466
RAD54_YEASTRAD54genetic
20093466
FAR10_YEASTFAR10genetic
20093466
ARL3_YEASTARL3genetic
20093466
BMH1_YEASTBMH1genetic
22484491
SSB1_YEASTSSB1physical
22940862
G3P3_YEASTTDH3physical
22940862
DED1_YEASTDED1physical
22940862
KPYK1_YEASTCDC19physical
22940862
HSP71_YEASTSSA1physical
22940862
HSP72_YEASTSSA2physical
22940862
ETR1_YEASTETR1genetic
27708008
NPL4_YEASTNPL4genetic
27708008
SSH1_YEASTSSH1genetic
27708008
MGR1_YEASTMGR1genetic
27708008
MAF1_YEASTMAF1genetic
27708008
RV167_YEASTRVS167genetic
27708008
STP1_YEASTSTP1genetic
27708008
MON1_YEASTMON1genetic
27708008
RAD54_YEASTRAD54genetic
27708008
DAL81_YEASTDAL81genetic
27708008
TGL3_YEASTTGL3genetic
27708008
MSN1_YEASTMSN1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TOK1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-119, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory