SFT1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SFT1_YEAST
• UniProt AC: P43682
• Protein Name: Protein transport protein SFT1
• Gene Name: SFT1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 97
• Subcellular Localization: Golgi apparatus membrane ; Single-pass type IV membrane protein .
• Protein Description: Vesicle SNARE required for retrograde transport within the Golgi complex..
• Protein Sequence: MSNSRYSQTESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSVINQMTDSLGSMFTDIKNSSSRLTRSLKAGNSIWRMVGLALLIFFILYTLFKLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSNSRYSQTESNND -CCCCCCCCCCCCCH	29.52	23749301
11	Phosphorylation	SRYSQTESNNDRKLE CCCCCCCCCCHHHHH	44.30	28889911
16	Ubiquitination	TESNNDRKLEGLANK CCCCCHHHHHHHHHH	54.47	23749301
23	Acetylation	KLEGLANKLATFRNI HHHHHHHHHHHHHHH	33.61	24489116
23	Ubiquitination	KLEGLANKLATFRNI HHHHHHHHHHHHHHH	33.61	24961812
40	Phosphorylation	EIGDRAVSDSSVINQ HHHHHCCCCHHHHHH	30.69	30377154
42	Phosphorylation	GDRAVSDSSVINQMT HHHCCCCHHHHHHHH	20.99	30377154
43	Phosphorylation	DRAVSDSSVINQMTD HHCCCCHHHHHHHHH	31.82	29136822
49	Phosphorylation	SSVINQMTDSLGSMF HHHHHHHHHHHHHHH	16.81	29136822
51	Phosphorylation	VINQMTDSLGSMFTD HHHHHHHHHHHHHHH	26.01	29136822
54	Phosphorylation	QMTDSLGSMFTDIKN HHHHHHHHHHHHHCC	18.93	29136822
57	Phosphorylation	DSLGSMFTDIKNSSS HHHHHHHHHHCCCCH	28.33	29136822
60	Ubiquitination	GSMFTDIKNSSSRLT HHHHHHHCCCCHHHH	54.29	23749301
62	Phosphorylation	MFTDIKNSSSRLTRS HHHHHCCCCHHHHHH	25.37	29136822
63	Phosphorylation	FTDIKNSSSRLTRSL HHHHCCCCHHHHHHH	28.95	29136822
64	Phosphorylation	TDIKNSSSRLTRSLK HHHCCCCHHHHHHHH	31.00	29136822

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SFT1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SFT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SFT1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BOS1_YEAST	BOS1	physical	11251068
BOS1_YEAST	BOS1	physical	10591633
GOSR1_YEAST	GOS1	physical	11251068
GOSR1_YEAST	GOS1	physical	10591633
SEC22_YEAST	SEC22	physical	11251068
SEC22_YEAST	SEC22	physical	10591633
SED5_YEAST	SED5	physical	11251068
SED5_YEAST	SED5	physical	10591633
VAM3_YEAST	VAM3	physical	11251068
YKT6_YEAST	YKT6	physical	11251068
YKT6_YEAST	YKT6	physical	10591633
PEP12_YEAST	PEP12	physical	10591633
SLY1_YEAST	SLY1	physical	15372079
BET1_YEAST	BET1	genetic	10591633
SNC2_YEAST	SNC2	genetic	10591633
SED5_YEAST	SED5	genetic	7596416
COG1_YEAST	COG1	physical	18086915
COG2_YEAST	COG2	physical	18086915
VTI1_YEAST	VTI1	genetic	9398683

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.