| UniProt ID | PTK1_YEAST | |
|---|---|---|
| UniProt AC | P36002 | |
| Protein Name | Serine/threonine-protein kinase PTK1/STK1 | |
| Gene Name | PTK1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 662 | |
| Subcellular Localization | ||
| Protein Description | Essential determinant for low-affinity spermidine transport.. | |
| Protein Sequence | MTVSHNHSTKISQQPISSVSAFKFFGKKLLSSSHGNKLKKKASLPPDFHSTSTNDSESSSPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTSISRGNRHSSTSRNLSNSKFSSERLVYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDGDSKIRMLPIPIVDPNEYLPDEMKEASIQLSDNFVFDDENKTIGWGGSCEVRKIRSKYRKKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTRGWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIRLHDRAFRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQGIETCVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFLKNRVPIRSMVDIAAHPSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQLATLTLSEEPPATPAPSAPSAPSARVRGHSPHRVVHHHLNIVNSLVHSSSAASSQVPAST | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 66 | Phosphorylation | SSPKLPNSLKTSRRA CCCCCCCCHHHHHHH | 29.33 | 19779198 | |
| 75 | Phosphorylation | KTSRRANSFAHTTNS HHHHHHHHCCCCCCC | 23.87 | 29136822 | |
| 82 | Phosphorylation | SFAHTTNSKRSLSSA HCCCCCCCCCCCCCC | 27.61 | 28889911 | |
| 88 | Phosphorylation | NSKRSLSSASTKILP CCCCCCCCCCCEECC | 31.37 | 27017623 | |
| 99 | Phosphorylation | KILPPAGSSTSISRG EECCCCCCCCCCCCC | 32.33 | 28889911 | |
| 100 | Phosphorylation | ILPPAGSSTSISRGN ECCCCCCCCCCCCCC | 25.84 | 30377154 | |
| 102 | Phosphorylation | PPAGSSTSISRGNRH CCCCCCCCCCCCCCC | 22.10 | 19779198 | |
| 104 | Phosphorylation | AGSSTSISRGNRHSS CCCCCCCCCCCCCCC | 33.62 | 24930733 | |
| 117 | Phosphorylation | SSTSRNLSNSKFSSE CCCCCCCCCCCCCCC | 42.48 | 22369663 | |
| 119 | Phosphorylation | TSRNLSNSKFSSERL CCCCCCCCCCCCCCE | 31.53 | 22369663 | |
| 122 | Phosphorylation | NLSNSKFSSERLVYN CCCCCCCCCCCEEEC | 34.72 | 22369663 | |
| 123 | Phosphorylation | LSNSKFSSERLVYNP CCCCCCCCCCEEECC | 29.84 | 22369663 | |
| 135 | Phosphorylation | YNPYGVSTPSTSLSS ECCCCCCCCCCCHHH | 20.89 | 21440633 | |
| 139 | Phosphorylation | GVSTPSTSLSSVSTS CCCCCCCCHHHCCCC | 30.50 | 21440633 | |
| 141 | Phosphorylation | STPSTSLSSVSTSMK CCCCCCHHHCCCCCC | 28.58 | 21551504 | |
| 142 | Phosphorylation | TPSTSLSSVSTSMKK CCCCCHHHCCCCCCC | 25.94 | 21551504 | |
| 146 | Phosphorylation | SLSSVSTSMKKDPDL CHHHCCCCCCCCCCC | 22.54 | 21551504 | |
| 270 | Phosphorylation | FLLVKVPTTVYTTRG EEEEECCCEEEECCC | 31.70 | 30377154 | |
| 274 | Phosphorylation | KVPTTVYTTRGWGFV ECCCEEEECCCCHHH | 12.99 | 30377154 | |
| 331 | Acetylation | GIAHRDLKPENVLLS CCCCCCCCHHHEEEC | 55.35 | 25381059 | |
| 374 | Phosphorylation | KCAGMIGSPPYAPPE HHHHCCCCCCCCCCC | 16.27 | 30377154 | |
| 377 | Phosphorylation | GMIGSPPYAPPEVMF HCCCCCCCCCCCEEE | 34.81 | 27017623 | |
| 385 | Phosphorylation | APPEVMFYDSKKHYD CCCCEEEECCHHCCC | 10.95 | 30377154 | |
| 387 | Phosphorylation | PEVMFYDSKKHYDTE CCEEEECCHHCCCCC | 32.02 | 30377154 | |
| 428 | Phosphorylation | IPFLESCSFDTGFRD HHHHHHCCCCCCCHH | 35.12 | 19779198 | |
| 431 | Phosphorylation | LESCSFDTGFRDYCD HHHCCCCCCCHHHHH | 35.89 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PTK1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PTK1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PTK1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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