| UniProt ID | SLD5_YEAST | |
|---|---|---|
| UniProt AC | Q03406 | |
| Protein Name | DNA replication complex GINS protein SLD5 | |
| Gene Name | SLD5 {ECO:0000312|SGD:S000002897} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 294 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Required for DNA replication. Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery.. | |
| Protein Sequence | MDINIDDILAELDKETTAVDSTKITQGSSSTTHRDANTIVGSSLDLNDKTQIYVSPQQDFSDLMKSWKNERCSPELLPYPHQLMKRLLNRISMQSQLIENISMGFLDMQNASNANPPMPNESKLPLLCMETELERLKFVIRSYIRCRLSKIDKFSLYLRQLNEDENSLISLTDLLSKDEIKYHDTHSLIWLKLVNDSILKYMPEELQAINDTEGSVNMIDEPDWNKFVFIHVNGPPDGKWNEDPLLQENEFGKPCYTVTIPDLKEEVELTIGSIYVMRYEVIRDLLRDDKVALI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 29 | Phosphorylation | TKITQGSSSTTHRDA CEECCCCCCCCCCCC | 38.23 | 30377154 | |
| 30 | Phosphorylation | KITQGSSSTTHRDAN EECCCCCCCCCCCCC | 38.74 | 28889911 | |
| 42 | Phosphorylation | DANTIVGSSLDLNDK CCCEEECCCCCCCCC | 19.48 | 22369663 | |
| 43 | Phosphorylation | ANTIVGSSLDLNDKT CCEEECCCCCCCCCC | 21.70 | 22369663 | |
| 197 | Phosphorylation | WLKLVNDSILKYMPE HHEHHCHHHHHHCHH | 25.31 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SLD5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SLD5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SLD5_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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