SNF8_YEAST - dbPTM
SNF8_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SNF8_YEAST
UniProt AC Q12483
Protein Name Vacuolar-sorting protein SNF8
Gene Name SNF8
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 233
Subcellular Localization Cytoplasm . Endosome membrane
Peripheral membrane protein .
Protein Description Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex..
Protein Sequence MKQFGLAAFDELKDGKYNDVNKTILEKQSVELRDQLMVFQERLVEFAKKHNSELQASPEFRSKFMHMCSSIGIDPLSLFDRDKHLFTVNDFYYEVCLKVIEICRQTKDMNGGVISFQELEKVHFRKLNVGLDDLEKSIDMLKSLECFEIFQIRGKKFLRSVPNELTSDQTKILEICSILGYSSISLLKANLGWEAVRSKSALDEMVANGLLWIDYQGGAEALYWDPSWITRQL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
160PhosphorylationRGKKFLRSVPNELTS
CCHHHHHCCCCCCCC		44.0429136822
166PhosphorylationRSVPNELTSDQTKIL
HCCCCCCCCCHHHHH		24.8729136822
167PhosphorylationSVPNELTSDQTKILE
CCCCCCCCCHHHHHH		40.1029136822
170PhosphorylationNELTSDQTKILEICS
CCCCCCHHHHHHHHH		25.6629136822
177PhosphorylationTKILEICSILGYSSI
HHHHHHHHHHCCCHH		26.8929136822
181PhosphorylationEICSILGYSSISLLK
HHHHHHCCCHHHHHH		8.8729136822
182PhosphorylationICSILGYSSISLLKA
HHHHHCCCHHHHHHH		21.2829136822
183PhosphorylationCSILGYSSISLLKAN
HHHHCCCHHHHHHHH		14.0229136822
185PhosphorylationILGYSSISLLKANLG
HHCCCHHHHHHHHHC		29.6029136822
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SNF8_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SNF8_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SNF8_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SNF7_YEASTSNF7physical
12194858
VPS24_YEASTVPS24physical
12194858
VPS20_YEASTVPS20physical
15086794
VPS28_YEASTVPS28physical
15086794
VPS36_YEASTVPS36physical
15086794
SRN2_YEASTSRN2physical
15086794
VPS36_YEASTVPS36physical
15469844
CYC8_YEASTCYC8genetic
7785322
PACC_YEASTRIM101genetic
16024810
OLA1_YEASTOLA1physical
16554755
VPS25_YEASTVPS25physical
16554755
VPS24_YEASTVPS24genetic
16227598
VPS25_YEASTVPS25physical
11283351
VPS36_YEASTVPS36physical
11283351
HSP71_YEASTSSA1physical
19536198
SSB1_YEASTSSB1physical
19536198
VPS36_YEASTVPS36physical
16371348
VPS20_YEASTVPS20physical
16371348
VPS36_YEASTVPS36physical
15329733
SRS2_YEASTSRS2genetic
21459050
ATN1_YEASTENA1genetic
18395523
UBC_HUMANUBCphysical
15029239
NYV1_YEASTNYV1genetic
25017437
ATC2_YEASTPMC1genetic
25017437
MIG1_YEASTMIG1genetic
25017437
NRG1_YEASTNRG1genetic
25017437
CANB_YEASTCNB1genetic
23933635
ATC1_YEASTPMR1genetic
23933635
PACC_YEASTRIM101genetic
23933635
NRG1_YEASTNRG1genetic
23933635
CDC1_YEASTCDC1genetic
27708008
APE3_YEASTAPE3genetic
27708008
SNF11_YEASTSNF11genetic
27708008
TRS85_YEASTTRS85genetic
27708008
GET2_YEASTGET2genetic
27708008
YER4_YEASTYER084Wgenetic
27708008
UBR1_YEASTUBR1genetic
27708008
CTM1_YEASTCTM1genetic
27708008
AIM25_YEASTAIM25genetic
27708008
VPS24_YEASTVPS24genetic
27708008
CDC24_YEASTCDC24genetic
27708008
KPC1_YEASTPKC1genetic
27708008
MCM7_YEASTMCM7genetic
27708008
NSE4_YEASTNSE4genetic
27708008
TIM22_YEASTTIM22genetic
27708008
UBC3_YEASTCDC34genetic
27708008
LCB2_YEASTLCB2genetic
27708008
TCPA_YEASTTCP1genetic
27708008
RIFK_YEASTFMN1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
DAM1_YEASTDAM1genetic
27708008
BRL1_YEASTBRL1genetic
27708008
YHS2_YEASTCIA2genetic
27708008
CDC23_YEASTCDC23genetic
27708008
CTF8_YEASTCTF8genetic
27708008
MET30_YEASTMET30genetic
27708008
OST1_YEASTOST1genetic
27708008
CDC6_YEASTCDC6genetic
27708008
KTHY_YEASTCDC8genetic
27708008
GFA1_YEASTGFA1genetic
27708008
NSE5_YEASTNSE5genetic
27708008
SEC65_YEASTSEC65genetic
27708008
HMCS_YEASTERG13genetic
27708008
VTI1_YEASTVTI1genetic
27708008
TAF7_YEASTTAF7genetic
27708008
LCB1_YEASTLCB1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
SYA_YEASTALA1genetic
27708008
NAB3_YEASTNAB3genetic
27708008
RTG3_YEASTRTG3genetic
27708008
SWC5_YEASTSWC5genetic
27708008
MTC4_YEASTMTC4genetic
27708008
STE50_YEASTSTE50genetic
27708008
BUD31_YEASTBUD31genetic
27708008
UBX3_YEASTUBX3genetic
27708008
YD157_YEASTYDL157Cgenetic
27708008
SPR6_YEASTSPR6genetic
27708008
BST1_YEASTBST1genetic
27708008
AP3B_YEASTAPL6genetic
27708008
YHK8_YEASTYHK8genetic
27708008
BCK1_YEASTBCK1genetic
27708008
RE107_YEASTREC107genetic
27708008
YJ24_YEASTKCH1genetic
27708008
STE24_YEASTSTE24genetic
27708008
SAC1_YEASTSAC1genetic
27708008
SNF7_YEASTSNF7genetic
27074665
PACC_YEASTRIM101genetic
26116211
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SNF8_YEAST

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Related Literatures of Post-Translational Modification

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