UniProt ID | CTM1_YEAST | |
---|---|---|
UniProt AC | P38818 | |
Protein Name | Cytochrome c lysine N-methyltransferase 1 | |
Gene Name | CTM1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 585 | |
Subcellular Localization | Cytoplasm, cytosol . | |
Protein Description | Methyltransferase which mediates trimethylation of 'Lys-78' of cytochrome c (CYC1).. | |
Protein Sequence | MEEVFRFYSNSRNIFIHKSLSLKPSTIDDPKSGYGLFVEPSKFKNDELKSETIQLLRIPKRCTFNINTLLALLGDEDEFSSKEEFQRTNDKIKIALREIMAHPNFSVFLTETNLLIIYFMIFQTIRSRYEIPENIQYYLENVLMSIEVETAMDSIENLATDYGHYPQIFGLRETLNLFKELFHDVLNLSDIKHLYSAIISRCLEIPERADTKSEEFTVHSTLVPIVDFANHEGTQKNAYFDIDPSNNDVLLLLDTKAVQSELTKPIEVFISYSPTEDLFSMLVTYGFTPDFRGNSQFWTVSFDRCFLRNYDGPDKTTNLRLFYKWMHINPVVPLVKYEHNGKTRWFLNDTTPEFDMLLLPFIPSIDDGKIARWAYDSTCHLMFTKIHCLINPEANEHALMIAENYRSLIKEKESNGDDFINLPPLAWSLRYKDTENDCVRQRHICSEDAVAVLKQEEMQDSTKTKSQFTSFFRKFLEFRRSKIIRPTSDSKVASILYQQELEIIADLAKAIDSSSTIFFSDLNVTLDTEPERLPPLRFLDDYIEISADKQEPSPICEDLSYYTPSRFTDFFQEEVSQYAAFFQDD | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
42 | Acetylation | GLFVEPSKFKNDELK CEEECCHHCCCHHHC | 71.69 | 24489116 | |
217 | Phosphorylation | DTKSEEFTVHSTLVP CCCCCCCEEECEEEE | 22.16 | 27017623 | |
220 | Phosphorylation | SEEFTVHSTLVPIVD CCCCEEECEEEEEEE | 21.07 | 27017623 | |
221 | Phosphorylation | EEFTVHSTLVPIVDF CCCEEECEEEEEEEE | 19.52 | 27017623 | |
239 | Phosphorylation | EGTQKNAYFDIDPSN CCCCCCEEEEECCCC | 15.92 | 29688323 | |
245 | Phosphorylation | AYFDIDPSNNDVLLL EEEEECCCCCEEEEE | 44.51 | 29688323 | |
255 | Phosphorylation | DVLLLLDTKAVQSEL EEEEEECCHHHHHHC | 22.37 | 29688323 | |
461 | Phosphorylation | KQEEMQDSTKTKSQF CHHHHCCCCCCHHHH | 18.21 | 21126336 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CTM1_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CTM1_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CTM1_YEAST !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
MCM7_YEAST | MCM7 | genetic | 27708008 | |
SCC1_YEAST | MCD1 | genetic | 27708008 | |
GPI19_YEAST | GPI19 | genetic | 27708008 | |
RMRP_YEAST | SNM1 | genetic | 27708008 | |
COG3_YEAST | COG3 | genetic | 27708008 | |
ACT_YEAST | ACT1 | genetic | 27708008 | |
DPOD2_YEAST | POL31 | genetic | 27708008 | |
YJ9I_YEAST | YJR141W | genetic | 27708008 | |
CD123_YEAST | CDC123 | genetic | 27708008 | |
TAD3_YEAST | TAD3 | genetic | 27708008 | |
ORC1_YEAST | ORC1 | genetic | 27708008 | |
MCM1_YEAST | MCM1 | genetic | 27708008 | |
ROT1_YEAST | ROT1 | genetic | 27708008 | |
LCB1_YEAST | LCB1 | genetic | 27708008 | |
NAB3_YEAST | NAB3 | genetic | 27708008 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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