CTM1_YEAST - dbPTM
CTM1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CTM1_YEAST
UniProt AC P38818
Protein Name Cytochrome c lysine N-methyltransferase 1
Gene Name CTM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 585
Subcellular Localization Cytoplasm, cytosol .
Protein Description Methyltransferase which mediates trimethylation of 'Lys-78' of cytochrome c (CYC1)..
Protein Sequence MEEVFRFYSNSRNIFIHKSLSLKPSTIDDPKSGYGLFVEPSKFKNDELKSETIQLLRIPKRCTFNINTLLALLGDEDEFSSKEEFQRTNDKIKIALREIMAHPNFSVFLTETNLLIIYFMIFQTIRSRYEIPENIQYYLENVLMSIEVETAMDSIENLATDYGHYPQIFGLRETLNLFKELFHDVLNLSDIKHLYSAIISRCLEIPERADTKSEEFTVHSTLVPIVDFANHEGTQKNAYFDIDPSNNDVLLLLDTKAVQSELTKPIEVFISYSPTEDLFSMLVTYGFTPDFRGNSQFWTVSFDRCFLRNYDGPDKTTNLRLFYKWMHINPVVPLVKYEHNGKTRWFLNDTTPEFDMLLLPFIPSIDDGKIARWAYDSTCHLMFTKIHCLINPEANEHALMIAENYRSLIKEKESNGDDFINLPPLAWSLRYKDTENDCVRQRHICSEDAVAVLKQEEMQDSTKTKSQFTSFFRKFLEFRRSKIIRPTSDSKVASILYQQELEIIADLAKAIDSSSTIFFSDLNVTLDTEPERLPPLRFLDDYIEISADKQEPSPICEDLSYYTPSRFTDFFQEEVSQYAAFFQDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
42AcetylationGLFVEPSKFKNDELK
CEEECCHHCCCHHHC
71.6924489116
217PhosphorylationDTKSEEFTVHSTLVP
CCCCCCCEEECEEEE
22.1627017623
220PhosphorylationSEEFTVHSTLVPIVD
CCCCEEECEEEEEEE
21.0727017623
221PhosphorylationEEFTVHSTLVPIVDF
CCCEEECEEEEEEEE
19.5227017623
239PhosphorylationEGTQKNAYFDIDPSN
CCCCCCEEEEECCCC
15.9229688323
245PhosphorylationAYFDIDPSNNDVLLL
EEEEECCCCCEEEEE
44.5129688323
255PhosphorylationDVLLLLDTKAVQSEL
EEEEEECCHHHHHHC
22.3729688323
461PhosphorylationKQEEMQDSTKTKSQF
CHHHHCCCCCCHHHH
18.2121126336

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CTM1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CTM1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CTM1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MCM7_YEASTMCM7genetic
27708008
SCC1_YEASTMCD1genetic
27708008
GPI19_YEASTGPI19genetic
27708008
RMRP_YEASTSNM1genetic
27708008
COG3_YEASTCOG3genetic
27708008
ACT_YEASTACT1genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
CD123_YEASTCDC123genetic
27708008
TAD3_YEASTTAD3genetic
27708008
ORC1_YEASTORC1genetic
27708008
MCM1_YEASTMCM1genetic
27708008
ROT1_YEASTROT1genetic
27708008
LCB1_YEASTLCB1genetic
27708008
NAB3_YEASTNAB3genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CTM1_YEAST

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Related Literatures of Post-Translational Modification

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