dbPTM

YHK8_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YHK8_YEAST
UniProt AC	P38776
Protein Name	Probable drug/proton antiporter YHK8
Gene Name	YHK8
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	514
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description	Probable drug/proton antiporter..
Protein Sequence	MVAEFQIASAQSSALTSTEEEHCSINSDKAAKLDLELTSERKNDGKQSHEVTFNEDIADPEDIARHMSTARRYYISSLITFTSMVITMISSSWTLPSTHIIEHFHISHEVSTLGITLYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFGSAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIGGALYHQSYKWTFITLLITSGCCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAVLEVTREQTSLLSAIFLSTKRPFGLLLRDRMMGVLCFYTGLELAIIYLYFVAFPYVFKKLYNFGPMEIACSYIGIMVGMILSAPTCLLFQKTFEWRVKRNNGVKTPEMRFEPLFYGAFLTPVGLFIFAFTCYKHVHWIAPIIGSAIFGSGVYFVFTGVFAYTVDAYRRYAASGMACNTFVRCIMAGVFPLFGLQMYKSMGVNWAGFLLAMVTVAMIPVPFLFTKYGARLRAKSPYAWDD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
27	Phosphorylation	EEHCSINSDKAAKLD HHHCCCCCCHHHHCC	38.53	28132839

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YHK8_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YHK8_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YHK8_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CHK1_YEAST	CHK1	genetic	27708008
SNF5_YEAST	SNF5	genetic	27708008
RTG2_YEAST	RTG2	genetic	27708008
PALA_YEAST	RIM20	genetic	27708008
SAW1_YEAST	SAW1	genetic	27708008
YBM6_YEAST	YBR016W	genetic	27708008
ETR1_YEAST	ETR1	genetic	27708008
CLPX_YEAST	MCX1	genetic	27708008
RMD9L_YEAST	YBR238C	genetic	27708008
YCR3_YEAST	YCR023C	genetic	27708008
RIM1_YEAST	RIM1	genetic	27708008
SNT1_YEAST	SNT1	genetic	27708008
RPN4_YEAST	RPN4	genetic	27708008
S2538_YEAST	YDL119C	genetic	27708008
PCL2_YEAST	PCL2	genetic	27708008
UFD2_YEAST	UFD2	genetic	27708008
TGL2_YEAST	TGL2	genetic	27708008
UBC13_YEAST	UBC13	genetic	27708008
ODO2_YEAST	KGD2	genetic	27708008
DHAS_YEAST	HOM2	genetic	27708008
INM2_YEAST	INM2	genetic	27708008
RQC1_YEAST	RQC1	genetic	27708008
XRS2_YEAST	XRS2	genetic	27708008
RSM28_YEAST	RSM28	genetic	27708008
ALDH5_YEAST	ALD5	genetic	27708008
IES5_YEAST	IES5	genetic	27708008
AIM11_YEAST	AIM11	genetic	27708008
RL24A_YEAST	RPL24A	genetic	27708008
MPC1_YEAST	MPC1	genetic	27708008
MTC3_YEAST	MTC3	genetic	27708008
RS25A_YEAST	RPS25A	genetic	27708008
YG29_YEAST	YGR066C	genetic	27708008
HSV2_YEAST	HSV2	genetic	27708008
DOT5_YEAST	DOT5	genetic	27708008
MTC1_YEAST	MTC1	genetic	27708008
SET2_YEAST	SET2	genetic	27708008
EMC2_YEAST	EMC2	genetic	27708008
VPS24_YEAST	VPS24	genetic	27708008
HAP4_YEAST	HAP4	genetic	27708008
SET3_YEAST	SET3	genetic	27708008
PTR2_YEAST	PTR2	genetic	27708008
VPS13_YEAST	VPS13	genetic	27708008
TAT2_YEAST	TAT2	genetic	27708008
VPS5_YEAST	VPS5	genetic	27708008
GAC1_YEAST	GAC1	genetic	27708008
TRM44_YEAST	TRM44	genetic	27708008
RTC6_YEAST	RTC6	genetic	27708008
MMT2_YEAST	MMT2	genetic	27708008
VPS4_YEAST	VPS4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YHK8_YEAST

Related Literatures of Post-Translational Modification