| UniProt ID | MSH5_YEAST | |
|---|---|---|
| UniProt AC | Q12175 | |
| Protein Name | MutS protein homolog 5 | |
| Gene Name | MSH5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 901 | |
| Subcellular Localization | ||
| Protein Description | Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis.. | |
| Protein Sequence | MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKRFKKWDLLQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGFFSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEEIFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGEDHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCGNLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 15 | Phosphorylation | SASETMRSIGNGEGL CHHHHHHHCCCCCCC | 24.83 | 27214570 | |
| 313 | Phosphorylation | KKRIETRYSIIRTLL CCHHHHHHHHHHHHH | 16.19 | 28889911 | |
| 318 | Phosphorylation | TRYSIIRTLLDKQNA HHHHHHHHHHHHCCE | 22.67 | 28889911 | |
| 735 | Phosphorylation | TDILDGPSLFGSIML CCCCCCHHHHHHHHH | 41.69 | 28889911 | |
| 739 | Phosphorylation | DGPSLFGSIMLNMSK CCHHHHHHHHHCCCC | 9.48 | 28889911 | |
| 745 | Phosphorylation | GSIMLNMSKSEKCPR HHHHHCCCCCCCCCC | 31.77 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MSH5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MSH5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MSH5_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HSL7_YEAST | HSL7 | physical | 10688190 | |
| MRE11_YEAST | MRE11 | physical | 10688190 | |
| MED3_YEAST | PGD1 | physical | 10688190 | |
| NDC80_YEAST | NDC80 | physical | 10688190 | |
| SPO74_YEAST | SPO74 | physical | 10688190 | |
| MSH4_YEAST | MSH4 | physical | 9374523 | |
| RAD24_YEAST | RAD24 | physical | 11825877 | |
| UBC4_YEAST | UBC4 | genetic | 17314980 | |
| SGS1_YEAST | SGS1 | genetic | 17662941 | |
| CSM4_YEAST | CSM4 | genetic | 18818741 | |
| ZIP1_YEAST | ZIP1 | genetic | 19816584 | |
| NDT80_YEAST | NDT80 | genetic | 24717437 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
