NDT80_YEAST - dbPTM
NDT80_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NDT80_YEAST
UniProt AC P38830
Protein Name Meiosis-specific transcription factor NDT80
Gene Name NDT80
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 627
Subcellular Localization Nucleus .
Protein Description Transcription factor required for successful completion of meiosis and spore formation. Gets activated after completion of meiotic recombination at the end of prophase I. Recognizes and binds to the middle sporulation element (MSE) 5'-C[AG]CAAA[AT]-3' in the promoter region of stage-specific genes that are required for progression through meiosis and sporulation. Competes for binding to MSE with the transcriptional repressor SUM1, which represses middle sporulation-specific genes during mitosis and early sporulation..
Protein Sequence MNEMENTDPVLQDDLVSKYERELSTEQEEDTPVILTQLNEDGTTSNYFDKRKLKIAPRSTLQFKVGPPFELVRDYCPVVESHTGRTLDLRIIPRIDRGFDHIDEEWVGYKRNYFTLVSTFETANCDLDTFLKSSFDLLVEDSSVESRLRVQYFAIKIKAKNDDDDTEINLVQHTAKRDKGPQFCPSVCPLVPSPLPKHQIIREASNVRNITKMKKYDSTFYLHRDHVNYEEYGVDSLLFSYPEDSIQKVARYERVQFASSISVKKPSQQNKHFSLHVILGAVVDPDTFHGENPGIPYDELALKNGSKGMFVYLQEMKTPPLIIRGRSPSNYASSQRITVRTPSSVNSSQNSTKRKMPSMAQPLNESCLNARPSKRRSKVALGAPNSGASISPIKSRQSTPMEASKENEDPFFRPNKRVETLEHIQNKLGALKNQCPDSSLKYPSSSSRGMEGCLEKEDLVYSSSFSVNMKQIELKPARSFEHENIFKVGSLAFKKINELPHENYDITIEKKSMEQNYLRPEIGSRSECKTSYGNELSLSNISFSILPNSAENFHLETALFPATEEDVPRTFSRILETGSFQNYYQKMDAENADRVYSKGVKLIASGTLPSGIFNREELFEEDSFYKY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59PhosphorylationKLKIAPRSTLQFKVG
CCEECCCCCCEEEEC		32.2027017623
60PhosphorylationLKIAPRSTLQFKVGP
CEECCCCCCEEEECC		26.3427017623
113PhosphorylationWVGYKRNYFTLVSTF
HHCCCCCEEEEEEEE		11.2830377154
115PhosphorylationGYKRNYFTLVSTFET
CCCCCEEEEEEEEEC		18.8530377154
118PhosphorylationRNYFTLVSTFETANC
CCEEEEEEEEECCCC		30.4130377154
122PhosphorylationTLVSTFETANCDLDT
EEEEEEECCCCCHHH		20.9830377154
386PhosphorylationVALGAPNSGASISPI
EECCCCCCCCCCCCC		34.3827214570
391PhosphorylationPNSGASISPIKSRQS
CCCCCCCCCCCCCCC		20.3427214570
461PhosphorylationLEKEDLVYSSSFSVN
ECHHHCEEEEEEEEE		15.3326447709
462PhosphorylationEKEDLVYSSSFSVNM
CHHHCEEEEEEEEEC		16.4226447709
463PhosphorylationKEDLVYSSSFSVNMK
HHHCEEEEEEEEECE		20.0926447709
464PhosphorylationEDLVYSSSFSVNMKQ
HHCEEEEEEEEECEE		18.6626447709
466PhosphorylationLVYSSSFSVNMKQIE
CEEEEEEEEECEEEE		17.9626447709
610PhosphorylationIASGTLPSGIFNREE
EEECCCCCCCCCHHH		47.8630377154
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NDT80_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NDT80_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NDT80_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UFD1_YEASTUFD1physical
16554755
UBP7_YEASTUBP7physical
16554755
YP117_YEASTYPR117Wphysical
16554755
RAD52_YEASTRAD52genetic
18313389
RIC1_YEASTRIC1genetic
19269370
HST1_YEASTHST1genetic
19528232
REC8_YEASTREC8genetic
20230747
MND2_YEASTMND2genetic
20230747
LEO1_YEASTLEO1genetic
20959818
SCC2_YEASTSCC2genetic
21508318
SGS1_YEASTSGS1genetic
21637791
SPO11_YEASTSPO11genetic
21637791
GLN3_YEASTGLN3genetic
21127252
REI1_YEASTREI1genetic
21127252
KCS1_YEASTKCS1genetic
21127252
PCH2_YEASTPCH2genetic
22072981
RAD17_YEASTRAD17genetic
22072981
CDC5_YEASTCDC5genetic
22500736
DAM1_YEASTDAM1genetic
22851650
ATR_YEASTMEC1genetic
24137535
CDC6_YEASTCDC6genetic
24137535
CST9_YEASTCST9genetic
23775120
DMC1_YEASTDMC1genetic
24367271
HED1_YEASTHED1genetic
24367271
RMRP_YEASTSNM1genetic
27708008
RPC6_YEASTRPC34genetic
27708008
ICS2_YEASTICS2genetic
27708008
SHG1_YEASTSHG1genetic
27708008
ARX1_YEASTARX1genetic
27708008
INO2_YEASTINO2genetic
27708008
AIM11_YEASTAIM11genetic
27708008
BFA1_YEASTBFA1genetic
27708008
PUR91_YEASTADE16genetic
27708008
SEI1_YEASTFLD1genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
ATP18_YEASTATP18genetic
27708008
PMS1_YEASTPMS1genetic
27708008
BUD21_YEASTBUD21genetic
27708008
WHI5_YEASTWHI5genetic
27708008
IES4_YEASTIES4genetic
27708008
DGK1_YEASTDGK1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
APC11_YEASTAPC11genetic
27708008
NSE4_YEASTNSE4genetic
27708008
UTP6_YEASTUTP6genetic
27708008
RSP5_YEASTRSP5genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SAD1_YEASTSAD1genetic
27708008
SPT16_YEASTSPT16genetic
27708008
SWC4_YEASTSWC4genetic
27708008
CDC6_YEASTCDC6genetic
27708008
CDC11_YEASTCDC11genetic
27708008
FIP1_YEASTFIP1genetic
27708008
PRS7_YEASTRPT1genetic
27708008
NSE1_YEASTNSE1genetic
27708008
CFT2_YEASTCFT2genetic
27708008
AFG2_YEASTAFG2genetic
27708008
CUS1_YEASTCUS1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
PP2C3_YEASTPTC3genetic
27708008
PP2C4_YEASTPTC4genetic
27708008
PAT1_YEASTPAT1genetic
27708008
MGMT_YEASTMGT1genetic
27708008
SLX8_YEASTSLX8genetic
27708008
TNA1_YEASTTNA1genetic
27708008
BTN1_YEASTYHC3genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
FABG_YEASTOAR1genetic
27708008
CTK1_YEASTCTK1genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
XDJ1_YEASTXDJ1genetic
27708008
CCW12_YEASTCCW12genetic
27708008
PEX13_YEASTPEX13genetic
27708008
ECM19_YEASTECM19genetic
27708008
RCM1_YEASTRCM1genetic
27708008
NM111_YEASTNMA111genetic
27708008
THI6_YEASTTHI6genetic
27708008
CDC5_YEASTCDC5genetic
28249986
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NDT80_YEAST

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Related Literatures of Post-Translational Modification

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