| UniProt ID | CST9_YEAST | |
|---|---|---|
| UniProt AC | Q06032 | |
| Protein Name | Chromosome stability protein 9 | |
| Gene Name | CST9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 482 | |
| Subcellular Localization | Nucleus. Chromosome. Synapsed meiotic chromosomes. | |
| Protein Description | Component of the synapsis initiation complex (SIC) necessary for the synaptonemal complex assembly. Stabilizes the ZIP2 component to the chromosomes. The SIC complex loads onto chromosomes and nucleates ZIP1 polymerization, a molecular zipper that acts to bring homologous chromosomes in close apposition, which is required for meiotic crossover. May also be involved in double strand break repair.. | |
| Protein Sequence | MGGYLAIVFIPQTNTKSMREKKQKCLKQVRRLSLISPKKYIMPDSIFEQPFVYCGVCHRRTSHGDPLRLTSCAHILCSQHSPLTSKVCPICRSSDISIINLVESKQLPTDIRIFFEPLPPLLESLYNVSQFQLNGLSKQCQYYQNHCLKLREKCARQQQLLYQAKIELDSMAILKKRIQELESVLNHNNVSSMSVGVLPTRNSHQNHYQPPPTVDLTVDDNSLEEFEAKSFIKKLKKNSSLRNSSKNNNGTVTPSTSGRVNKNQPLFMETLNNPNRNSIPPPGMNPNANSNLPNISTIAESTNLNRFSFSPVRVAKGFDGKLPNLDILTNNGSVSSKNISRLSSASLQPSSPLSSSSNRLILPNSNLKELHHSNTPLTSTSTQFPSALEKLKITRKRNNTISGSNRITHNLSSHVRSSGLAFSSSSNSLQQSKLPKSNILKRSNSTQQLTNTHLKSDNHLPPRSSNTVLGSSKKNNKFRRIR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 97 | Phosphorylation | ICRSSDISIINLVES HHCCCCCEEEEHHHC | 23.54 | 27214570 | |
| 183 | Phosphorylation | KRIQELESVLNHNNV HHHHHHHHHHCCCCC | 44.52 | 19779198 | |
| 222 | Phosphorylation | DLTVDDNSLEEFEAK EEEECCCCHHHHHHH | 44.12 | 28889911 | |
| 230 | Phosphorylation | LEEFEAKSFIKKLKK HHHHHHHHHHHHHHH | 38.97 | 28889911 | |
| 253 | Phosphorylation | KNNNGTVTPSTSGRV CCCCCCCCCCCCCCC | 16.03 | 27214570 | |
| 310 | Phosphorylation | NLNRFSFSPVRVAKG CCCCCCCCCEEECCC | 22.68 | 27214570 | |
| 351 | Phosphorylation | SASLQPSSPLSSSSN CCCCCCCCCCCCCCC | 36.22 | 27214570 | |
| 423 | Phosphorylation | RSSGLAFSSSSNSLQ HHCCCCCCCCCCHHH | 24.57 | 27214570 | |
| 445 | Phosphorylation | NILKRSNSTQQLTNT HHHHCCCCCHHHCHH | 28.92 | 27214570 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CST9_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CST9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CST9_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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