UGA2_YEAST - dbPTM
UGA2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UGA2_YEAST
UniProt AC P38067
Protein Name Succinate-semialdehyde dehydrogenase [NADP(+)]
Gene Name UGA2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 497
Subcellular Localization
Protein Description
Protein Sequence MTLSKYSKPTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITIGNLPNSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
212PhosphorylationKAGFPKGSFNVILSH
HHCCCCCCEEEEECC		21.5522369663
218PhosphorylationGSFNVILSHANTPKL
CCEEEEECCCCCCCC		14.9422369663
222PhosphorylationVILSHANTPKLGKTL
EEECCCCCCCCCCCC		23.6822369663
224AcetylationLSHANTPKLGKTLCE
ECCCCCCCCCCCCCC		68.7624489116
241PhosphorylationKVKKVTFTGSTNVGK
CCEEEEEECCCCHHH		22.3627017623
243PhosphorylationKKVTFTGSTNVGKIL
EEEEEECCCCHHHHH		17.4727017623
244PhosphorylationKVTFTGSTNVGKILM
EEEEECCCCHHHHHE		34.9627017623
313AcetylationVHSSIIDKFAKLLAE
EEHHHHHHHHHHHHH		36.4924489116
316AcetylationSIIDKFAKLLAERVK
HHHHHHHHHHHHHHH		47.3622865919
468PhosphorylationPFGGVKESGFGREGS
CCCCCCCCCCCCCCC		33.4322369663
475PhosphorylationSGFGREGSLYGIEDY
CCCCCCCCEECCCCE		17.4222369663
477PhosphorylationFGREGSLYGIEDYTV
CCCCCCEECCCCEEE		20.1122369663
496PhosphorylationTIGNLPNSI------
EECCCCCCC------		27.9521440633
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UGA2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UGA2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UGA2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RLA4_YEASTRPP2Bphysical
10688190
YKC3_YEASTYKL023Wphysical
10688190
UGA2_YEASTUGA2physical
18467557
VPS21_YEASTVPS21physical
18467557
UGA2_YEASTUGA2physical
18719252
UGA2_YEASTUGA2physical
22615397
YJ90_YEASTYJR120Wgenetic
27708008
SWC4_YEASTSWC4genetic
27708008
SEC22_YEASTSEC22genetic
27708008
ECM1_YEASTECM1genetic
27708008
SHG1_YEASTSHG1genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
SWI4_YEASTSWI4genetic
27708008
DBF2_YEASTDBF2genetic
27708008
OPI1_YEASTOPI1genetic
27708008
YL278_YEASTYLR278Cgenetic
27708008
EFM7_YEASTNNT1genetic
27708008
NEW1_YEASTNEW1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UGA2_YEAST

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Related Literatures of Post-Translational Modification

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