MRS2_YEAST - dbPTM
MRS2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MRS2_YEAST
UniProt AC Q01926
Protein Name Magnesium transporter MRS2, mitochondrial
Gene Name MRS2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 470
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. [PubMed: 12628916]
Protein Sequence MNRRLLVRSISCFQPLSRITFGRPNTPFLRKYADTSTAANTNSTILRKQLLSLKPISASDSLFISCTVFNSKGNIISMSEKFPKWSFLTEHSLFPRDLRKIDNSSIDIIPTIMCKPNCIVINLLHIKALIERDKVYVFDTTNPSAAAKLSVLMYDLESKLSSTKNNSQFYEHRALESIFINVMSALETDFKLHSQICIQILNDLENEVNRLKLRHLLIKSKDLTLFYQKTLLIRDLLDELLENDDDLANMYLTVKKSPKDNFSDLEMLIETYYTQCDEYVQQSESLIQDIKSTEEIVNIILDANRNSLMLLELKVTIYTLGFTVASVLPAFYGMNLKNFIEESEWGFTSVAVFSIVSALYITKKNFNSLRSVTKMTMYPNSPANSSVYPKTSASIALTNKLKRRRKWWKSTKQRLGVLLYGSSYTNKANLSNNKINKGFSKVKKFNMENDIKNKQNRDMIWKWLIEDKKN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationRLLVRSISCFQPLSR
HHEEEEECCCCCHHH		15.3227017623
17PhosphorylationISCFQPLSRITFGRP
ECCCCCHHHCCCCCC		28.4627017623
141PhosphorylationKVYVFDTTNPSAAAK
CEEEEECCCHHHHHH		47.1528889911
220PhosphorylationLRHLLIKSKDLTLFY
HHHHHHHCCCCHHHH		25.1428889911
373PhosphorylationFNSLRSVTKMTMYPN
CCCCCCEEEEEECCC		19.1527017623
376PhosphorylationLRSVTKMTMYPNSPA
CCCEEEEEECCCCCC		18.3427017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MRS2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MRS2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MRS2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ALR1_YEASTALR1genetic
11544180
MRS3_YEASTMRS3genetic
11544180
MRS3_YEASTMRS3genetic
8252639
MRS4_YEASTMRS4genetic
11544180
MRS4_YEASTMRS4genetic
8252639
RAEP_YEASTMRS6genetic
7882424
RIM2_YEASTRIM2genetic
7891656
TIM12_YEASTTIM12genetic
8663351
YIQ9_YEASTYIL169Cphysical
16554755
SUE1_YEASTSUE1physical
16554755
LONM_YEASTPIM1genetic
21987634
ATPA_YEASTATP1genetic
21987634
CSG2_YEASTCSG2genetic
21987634
C1TM_YEASTMIS1genetic
21987634
ODPB_YEASTPDB1genetic
21987634
RV167_YEASTRVS167genetic
21987634
SNF1_YEASTSNF1genetic
21987634
ODPA_YEASTPDA1genetic
21987634
AAKG_YEASTSNF4genetic
21987634
PTH_YEASTPTH1genetic
21987634
ATP12_YEASTATP12genetic
21987634
ALF_YEASTFBA1genetic
21987634
ACON_YEASTACO1genetic
21987634
VIP1_YEASTVIP1genetic
21987634
MSS1_YEASTMSS1genetic
21987634
ODP2_YEASTLAT1genetic
21987634
PSD1_YEASTPSD1genetic
21987634
IF2M_YEASTIFM1genetic
21987634
MDM38_YEASTMDM38genetic
21987634
GEP3_YEASTGEP3genetic
21987634
MOD5_YEASTMOD5genetic
21987634
YME1_YEASTYME1genetic
21987634
SPC72_YEASTSPC72physical
22875988
ARE1_YEASTARE1physical
22875988
RSC8_YEASTRSC8physical
22875988
SEC9_YEASTSEC9physical
22875988
SPR3_YEASTSPR3physical
22875988
SGM1_YEASTSGM1physical
22875988
RNA1_YEASTRNA1physical
22875988
YM39_YEASTYMR166Cgenetic
25585246
RM01_YEASTMRPL1genetic
27708008
RM49_YEASTMRP49genetic
27708008
RM39_YEASTMRPL39genetic
27708008
PEX22_YEASTPEX22genetic
27708008
SLA1_YEASTSLA1genetic
27708008
FMT_YEASTFMT1genetic
27708008
SEF1_YEASTSEF1genetic
27708008
C1TM_YEASTMIS1genetic
27708008
ODPB_YEASTPDB1genetic
27708008
NAA38_YEASTMAK31genetic
27708008
THRC_YEASTTHR4genetic
27708008
PAT1_YEASTPAT1genetic
27708008
PDP2_YEASTPTC6genetic
27708008
PEX19_YEASTPEX19genetic
27708008
PEX5_YEASTPEX5genetic
27708008
PEX10_YEASTPEX10genetic
27708008
IPK1_YEASTIPK1genetic
27708008
PEX3_YEASTPEX3genetic
27708008
BCS1_YEASTBCS1genetic
27708008
LSM6_YEASTLSM6genetic
27708008
SNF1_YEASTSNF1genetic
27708008
UBP3_YEASTUBP3genetic
27708008
RAD4_YEASTRAD4genetic
27708008
ODPA_YEASTPDA1genetic
27708008
SWP82_YEASTSWP82genetic
27708008
PEX14_YEASTPEX14genetic
27708008
RTG2_YEASTRTG2genetic
27708008
PEX8_YEASTPEX8genetic
27708008
UBCX_YEASTPEX4genetic
27708008
CBP4_YEASTCBP4genetic
27708008
ELP2_YEASTELP2genetic
27708008
PTH_YEASTPTH1genetic
27708008
VID28_YEASTVID28genetic
27708008
SDS3_YEASTSDS3genetic
27708008
FLX1_YEASTFLX1genetic
27708008
LSM1_YEASTLSM1genetic
27708008
PEX2_YEASTPEX2genetic
27708008
AATM_YEASTAAT1genetic
27708008
HAP4_YEASTHAP4genetic
27708008
COXM1_YEASTCMC1genetic
27708008
PEX1_YEASTPEX1genetic
27708008
SAC1_YEASTSAC1genetic
27708008
BAS1_YEASTBAS1genetic
27708008
IZH3_YEASTIZH3genetic
27708008
PEX13_YEASTPEX13genetic
27708008
VIP1_YEASTVIP1genetic
27708008
VPS9_YEASTVPS9genetic
27708008
MSS1_YEASTMSS1genetic
27708008
PEX12_YEASTPEX12genetic
27708008
IMP2_YEASTIMP2genetic
27708008
GID8_YEASTGID8genetic
27708008
IDH1_YEASTIDH1genetic
27708008
ODP2_YEASTLAT1genetic
27708008
MKS1_YEASTMKS1genetic
27708008
NST1_YEASTNST1genetic
27708008
MDM38_YEASTMDM38genetic
27708008
PEX15_YEASTPEX15genetic
27708008
RTG1_YEASTRTG1genetic
27708008
WHI2_YEASTWHI2genetic
27708008
HUT1_YEASTHUT1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MRS2_YEAST

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Related Literatures of Post-Translational Modification

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