dbPTM

DMC1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DMC1_YEAST
UniProt AC	P25453
Protein Name	Meiotic recombination protein DMC1
Gene Name	DMC1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	334
Subcellular Localization	Nucleus .
Protein Description	Required for meiotic recombination, synaptonemal complex formation and cell cycle progression. Recruited to meiosis recombination hotspots by MEI5 and SAE3..
Protein Sequence	MSVTGTEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of DMC1_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DMC1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DMC1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DMC1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VDAC1_YEAST	POR1	physical	11805837
RUVB2_YEAST	RVB2	physical	11805837
NOP14_YEAST	NOP14	physical	11805837
TRPG_YEAST	TRP3	physical	11805837
ACAC_YEAST	ACC1	physical	11805837
DPM1_YEAST	DPM1	physical	11805837
MDJ1_YEAST	MDJ1	physical	11805837
DMC1_YEAST	DMC1	physical	10688190
DMC1_YEAST	DMC1	physical	9335591
RDH54_YEAST	RDH54	physical	9335591
NDC80_YEAST	NDC80	physical	9335591
PDC1_YEAST	PDC1	physical	9335591
PT309_YEAST	PET309	physical	9335591
APC2_YEAST	APC2	physical	9335591
PDC5_YEAST	PDC5	physical	9335591
ACAC_YEAST	ACC1	physical	9335591
ULS1_YEAST	ULS1	physical	9335591
MEI5_YEAST	MEI5	physical	15620352
RAD51_YEAST	RAD51	genetic	14667413
RAD54_YEAST	RAD54	genetic	10526232
ATR_YEAST	MEC1	genetic	10511543
MEK1_YEAST	MEK1	genetic	9000054
PCH2_YEAST	PCH2	genetic	10319812
RAD17_YEAST	RAD17	genetic	12192042
RAD17_YEAST	RAD17	genetic	10511543
RAD24_YEAST	RAD24	genetic	10511543
RED1_YEAST	RED1	genetic	9000054
MRE11_YEAST	MRE11	physical	16554755
DMC1_YEAST	DMC1	physical	16581767
HED1_YEAST	HED1	genetic	16818607
RAD51_YEAST	RAD51	genetic	16818607
DMC1_YEAST	DMC1	physical	16818607
RFA1_YEAST	RFA1	genetic	17314980
PCNA_YEAST	POL30	genetic	17314980
DMC1_YEAST	DMC1	physical	11283351
NDT80_YEAST	NDT80	genetic	12192042
RE114_YEAST	REC114	genetic	10526232
CG21_YEAST	CLB1	genetic	10619027
DMC1_YEAST	DMC1	physical	18535008
SPO11_YEAST	SPO11	genetic	19116279
RAD17_YEAST	RAD17	genetic	19116279
DOT1_YEAST	DOT1	genetic	11029058
RAD17_YEAST	RAD17	genetic	20237423
SUM1_YEAST	SUM1	genetic	20237423
FKBP3_YEAST	FPR3	genetic	20237423
RAD54_YEAST	RAD54	genetic	12702674
PCH2_YEAST	PCH2	genetic	15120066
MEK1_YEAST	MEK1	genetic	20421598
REC8_YEAST	REC8	genetic	20421598
RED1_YEAST	RED1	genetic	20534433
PCH2_YEAST	PCH2	genetic	21515575
SPO11_YEAST	SPO11	genetic	21515575
NDT80_YEAST	NDT80	genetic	21471004
LCD1_YEAST	LCD1	genetic	21693576
SPO11_YEAST	SPO11	genetic	21693576
CDC5_YEAST	CDC5	genetic	21795394
RDH54_YEAST	RDH54	physical	22761450
RAD54_YEAST	RAD54	physical	22761450
PCH2_YEAST	PCH2	genetic	22745819
RAD54_YEAST	RAD54	physical	23769192
RDH54_YEAST	RDH54	physical	23769192
FKBP3_YEAST	FPR3	genetic	24385939
HED1_YEAST	HED1	genetic	24367271
RAD53_YEAST	RAD53	genetic	24183725
RAD54_YEAST	RAD54	genetic	24183725
RRM3_YEAST	RRM3	genetic	27708008
SLX5_YEAST	SLX5	genetic	27708008
AP3B_YEAST	APL6	genetic	27708008
YNO0_YEAST	YNL140C	genetic	27708008
COQ10_YEAST	COQ10	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
RTC1_YEAST	RTC1	genetic	27708008
GUP2_YEAST	GUP2	genetic	27708008
ATR_YEAST	MEC1	genetic	27678521
MEK1_YEAST	MEK1	genetic	27678521
RED1_YEAST	RED1	genetic	27678521
HOP1_YEAST	HOP1	genetic	27678521
PCH2_YEAST	PCH2	genetic	27678521
H2A1_YEAST	HTA1	genetic	27678521
H2A2_YEAST	HTA2	genetic	27678521
DOT1_YEAST	DOT1	genetic	27678521
DBF4_YEAST	DBF4	genetic	27678521
SLD3_YEAST	SLD3	genetic	27678521
HOP1_YEAST	HOP1	genetic	26225562
HED1_YEAST	HED1	genetic	27483004
UBC9_HUMAN	UBE2I	physical	27107014
DMC1_YEAST	DMC1	physical	24465215
RAD54_YEAST	RAD54	genetic	24465215
HED1_YEAST	HED1	genetic	24465215

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DMC1_YEAST

Related Literatures of Post-Translational Modification