ZRT2_YEAST - dbPTM
ZRT2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZRT2_YEAST
UniProt AC Q12436
Protein Name Zinc-regulated transporter 2
Gene Name ZRT2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 422
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Low-affinity zinc transport protein. Active in zinc-replete cells and is time-, temperature- and concentration-dependent and prefers zinc over other metals as its substrate..
Protein Sequence MVDLIARDDSVDTCQASNGYNGHAGLRILAVFIILISSGLGVYFPILSSRYSFIRLPNWCFFIAKFFGSGVIVATAFVHLLQPAAEALGDECLGGTFAEYPWAFGICLMSLFLLFFTEIITHYFVAKTLGHDHGDHGEVTSIDVDAPSSGFVIRNMDSDPVSFNNEAAYSIHNDKTPYTTRNEEIVATPIKEKEPGSNVTNYDLEPGKTESLANELVPTSSHATNLASVPGKDHYSHENDHQDVSQLATRIEEEDKEQYLNQILAVFILEFGIIFHSVFVGLSLSVAGEEFETLFIVLTFHQMFEGLGLGTRVAETNWPESKKYMPWLMGLAFTLTSPIAVAVGIGVRHSWIPGSRRALIANGVFDSISSGILIYTGLVELMAHEFLYSNQFKGPDGLKKMLSAYLIMCCGAALMALLGKWA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
128PhosphorylationTHYFVAKTLGHDHGD
HHHHHHHHHCCCCCC		28.3819779198
140PhosphorylationHGDHGEVTSIDVDAP
CCCCCEEEEEEEECC		18.7019779198
141PhosphorylationGDHGEVTSIDVDAPS
CCCCEEEEEEEECCC		23.2023749301
148PhosphorylationSIDVDAPSSGFVIRN
EEEEECCCCCEEEEE		44.8328889911
149PhosphorylationIDVDAPSSGFVIRNM
EEEECCCCCEEEEEC		34.8828889911
158PhosphorylationFVIRNMDSDPVSFNN
EEEEECCCCCCCCCC		32.8023749301
162PhosphorylationNMDSDPVSFNNEAAY
ECCCCCCCCCCCCHH		27.8722369663
169PhosphorylationSFNNEAAYSIHNDKT
CCCCCCHHHHCCCCC		18.4023749301
170PhosphorylationFNNEAAYSIHNDKTP
CCCCCHHHHCCCCCC		16.7924909858
175UbiquitinationAYSIHNDKTPYTTRN
HHHHCCCCCCCCCCC		57.6323749301
176PhosphorylationYSIHNDKTPYTTRNE
HHHCCCCCCCCCCCC		25.1321440633
179PhosphorylationHNDKTPYTTRNEEIV
CCCCCCCCCCCCEEE		22.0827017623
180PhosphorylationNDKTPYTTRNEEIVA
CCCCCCCCCCCEEEE		26.1727017623
188PhosphorylationRNEEIVATPIKEKEP
CCCEEEEEECCCCCC		18.0422369663
191UbiquitinationEIVATPIKEKEPGSN
EEEEEECCCCCCCCC		65.0323749301
193UbiquitinationVATPIKEKEPGSNVT
EEEECCCCCCCCCCC		65.2923749301
197PhosphorylationIKEKEPGSNVTNYDL
CCCCCCCCCCCCCCC		38.5521551504
200PhosphorylationKEPGSNVTNYDLEPG
CCCCCCCCCCCCCCC		32.1021551504
202PhosphorylationPGSNVTNYDLEPGKT
CCCCCCCCCCCCCCC		16.7324961812
209PhosphorylationYDLEPGKTESLANEL
CCCCCCCCHHHHHHC		36.4022890988
211PhosphorylationLEPGKTESLANELVP
CCCCCCHHHHHHCCC		37.7022890988
219PhosphorylationLANELVPTSSHATNL
HHHHCCCCCCCCCCC		35.0722890988
220PhosphorylationANELVPTSSHATNLA
HHHCCCCCCCCCCCC		17.6622890988
221PhosphorylationNELVPTSSHATNLAS
HHCCCCCCCCCCCCC		21.4422890988
224PhosphorylationVPTSSHATNLASVPG
CCCCCCCCCCCCCCC		25.9122890988
228PhosphorylationSHATNLASVPGKDHY
CCCCCCCCCCCCCCC		31.8222890988
235PhosphorylationSVPGKDHYSHENDHQ
CCCCCCCCCCCCCCC		23.1225533186
236PhosphorylationVPGKDHYSHENDHQD
CCCCCCCCCCCCCCC		22.3928889911
245PhosphorylationENDHQDVSQLATRIE
CCCCCCHHHHHHHCC		27.9728889911
249PhosphorylationQDVSQLATRIEEEDK
CCHHHHHHHCCHHHH		40.5524961812
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZRT2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZRT2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZRT2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CP56_YEASTDIT2genetic
20093466
ZRT1_YEASTZRT1genetic
20093466
RTG2_YEASTRTG2genetic
20093466
MED5_YEASTNUT1genetic
20093466
SOK2_YEASTSOK2genetic
20093466
YAR1_YEASTYAR1genetic
20093466
SUR1_YEASTSUR1genetic
20093466
UME6_YEASTUME6genetic
27708008
CP56_YEASTDIT2genetic
27708008
MED5_YEASTNUT1genetic
27708008
DAL81_YEASTDAL81genetic
27708008
CANB_YEASTCNB1genetic
27708008
FPS1_YEASTFPS1genetic
27708008
SOK2_YEASTSOK2genetic
27708008
TMA23_YEASTTMA23genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZRT2_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory