DTD_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DTD_YEAST
• UniProt AC: Q07648
• Protein Name: D-aminoacyl-tRNA deacylase {ECO:0000250|UniProtKB:Q8IIS0}
• Gene Name: DTD1 {ECO:0000303|PubMed:10766779}
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 150
• Subcellular Localization: Cytoplasm .
• Protein Description: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs (Probable). Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). [PubMed: 10766779 May also deacylate mischarged D-leucyl-tRNA(Leu)]
• Protein Sequence: MKIVLQKVSQASVVVDSKVISSIKHGYMLLVGISIDDSMAEIDKLSKKVLSLRIFEDESRNLWKKNIKEANGEILSVSQFTLMAKTKKGTKPDFHLAQKGHIAKELYEEFLKLLRSDLGEEKVKDGEFGAMMSCSLTNEGPVTIILDSDQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Ubiquitination	-MKIVLQKVSQASVV -CCEEEEECCCCEEE	39.43	24961812
104	Acetylation	AQKGHIAKELYEEFL HHHCCHHHHHHHHHH	47.88	24489116
133	Phosphorylation	GEFGAMMSCSLTNEG CCCEEEEEEECCCCC	6.35	27017623
135	Phosphorylation	FGAMMSCSLTNEGPV CEEEEEEECCCCCCE	30.81	27017623
148	Phosphorylation	PVTIILDSDQ----- CEEEEEECCC-----	34.17	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DTD_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DTD_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DTD_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PP11_YEAST	SIT4	physical	11805826
RIC1_YEAST	RIC1	genetic	19061648
MAK21_YEAST	MAK21	genetic	19061648
RPA14_YEAST	RPA14	genetic	19061648
BUD21_YEAST	BUD21	genetic	19061648
PFD5_YEAST	GIM5	genetic	19061648
TMA23_YEAST	TMA23	genetic	19061648
UTP9_YEAST	UTP9	genetic	19061648
SEH1_YEAST	SEH1	genetic	19061648
SN114_YEAST	SNU114	genetic	19061648
HIR2_YEAST	HIR2	genetic	19061648
EAF5_YEAST	EAF5	genetic	19061648
PFD2_YEAST	GIM4	genetic	19061648
MRM2_YEAST	MRM2	genetic	27708008
DCR2_YEAST	DCR2	genetic	27708008
PEX12_YEAST	PEX12	genetic	27708008
RCR1_YEAST	RCR1	genetic	27708008
EF1A_YEAST	TEF2	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
MCM21_YEAST	MCM21	genetic	27708008
SHO1_YEAST	SHO1	genetic	27708008
DDI1_YEAST	DDI1	genetic	27708008
AUA1_YEAST	AUA1	genetic	27708008
ATG1_YEAST	ATG1	genetic	27708008
CLG1_YEAST	CLG1	genetic	27708008
SAY1_YEAST	SAY1	genetic	27708008
YG5L_YEAST	YGR266W	genetic	27708008
QCR10_YEAST	QCR10	genetic	27708008
VPS29_YEAST	VPS29	genetic	27708008
PTH_YEAST	PTH1	genetic	27708008
AXL2_YEAST	AXL2	genetic	27708008
MNN11_YEAST	MNN11	genetic	27708008
ILM1_YEAST	ILM1	genetic	27708008
IXR1_YEAST	IXR1	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
FRMSR_YEAST	YKL069W	genetic	27708008
FEN1_YEAST	RAD27	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
METW_YEAST	YLL058W	genetic	27708008
PSR2_YEAST	PSR2	genetic	27708008
RIC1_YEAST	RIC1	genetic	27708008
EIF3J_YEAST	HCR1	genetic	27708008
OGG1_YEAST	OGG1	genetic	27708008
SAM37_YEAST	SAM37	genetic	27708008
PALI_YEAST	RIM9	genetic	27708008
YM35_YEAST	YMR160W	genetic	27708008
INP2_YEAST	INP2	genetic	27708008
RAD14_YEAST	RAD14	genetic	27708008
TMA23_YEAST	TMA23	genetic	27708008
RNH2A_YEAST	RNH201	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
NIP80_YEAST	NIP100	genetic	27708008
OPY2_YEAST	OPY2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.