| UniProt ID | ATG23_YEAST | |
|---|---|---|
| UniProt AC | Q06671 | |
| Protein Name | Autophagy-related protein 23 | |
| Gene Name | ATG23 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 453 | |
| Subcellular Localization |
Cytoplasm. Preautophagosomal structure membrane Peripheral membrane protein. Membrane Peripheral membrane protein. Found in pre-autophagosomal structure and other punctate structures. Correct localization of ATG23 to the membranes is strictly depen |
|
| Protein Description | Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9. Plays also a role in regulation of filamentous growth.. | |
| Protein Sequence | MELNQVLEKKEQILQYLGTLVGLHEKALSDVNSASQVTSIRKDITICLNDLCRINDLLVSHDGLLKREIGSLLRDKQELLELNEREQLLWKERKSWHIKQETDAAPADYVIDKDAIITISSHHRTSLNKYIESVGAENTILSNTDDSDAMIEEVQNAESSADQMIRNYKLLQLSHKQAKSEIIRLETLLRDFKKDNKFIEEELKRQSGRIRSEMGNIDFHLSKIEESKHQLMKRIGFESPLTQEKSLSEKIFNLRLSSADEDYNERQTINMKNFVHMKDLIELKIEDLQEQLMRNKNESSTVLTQRELWLDCQKKVGDLESKLITKLRSSSNSKIPPNEMSEMINSTIQYLNNLLDSSDEKLTTTLISNERDVLSKACEELHSESTTAQDGSSALPSKPIDIHKSHKGSNASSNLKQPSTPSFLVASKSPPKIGISESVVNANKNDAISKKVE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 222 | Phosphorylation | GNIDFHLSKIEESKH CCCHHHHHHHHHHHH | 24.02 | 27017623 | |
| 227 | Phosphorylation | HLSKIEESKHQLMKR HHHHHHHHHHHHHHH | 23.73 | 27017623 | |
| 239 | Phosphorylation | MKRIGFESPLTQEKS HHHHCCCCCCCCCCC | 23.97 | 21440633 | |
| 321 | Phosphorylation | KKVGDLESKLITKLR HHHCCHHHHHHHHHH | 39.81 | 27017623 | |
| 329 | Phosphorylation | KLITKLRSSSNSKIP HHHHHHHHCCCCCCC | 48.86 | 28889911 | |
| 330 | Phosphorylation | LITKLRSSSNSKIPP HHHHHHHCCCCCCCH | 27.40 | 28889911 | |
| 409 | Phosphorylation | IHKSHKGSNASSNLK CCHHCCCCCCCCCCC | 33.74 | 27017623 | |
| 413 | Phosphorylation | HKGSNASSNLKQPST CCCCCCCCCCCCCCC | 43.71 | 27017623 | |
| 419 | Phosphorylation | SSNLKQPSTPSFLVA CCCCCCCCCCCEEEE | 50.92 | 22369663 | |
| 420 | Phosphorylation | SNLKQPSTPSFLVAS CCCCCCCCCCEEEEC | 29.63 | 22369663 | |
| 422 | Phosphorylation | LKQPSTPSFLVASKS CCCCCCCCEEEECCC | 31.16 | 22369663 | |
| 427 | Phosphorylation | TPSFLVASKSPPKIG CCCEEEECCCCCCCC | 26.62 | 22369663 | |
| 429 | Phosphorylation | SFLVASKSPPKIGIS CEEEECCCCCCCCCC | 43.89 | 22369663 | |
| 436 | Phosphorylation | SPPKIGISESVVNAN CCCCCCCCHHHHCCC | 20.71 | 22369663 | |
| 438 | Phosphorylation | PKIGISESVVNANKN CCCCCCHHHHCCCCC | 25.28 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ATG23_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATG23_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATG23_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
