YN94_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YN94_YEAST
• UniProt AC: P53751
• Protein Name: Uncharacterized membrane glycoprotein YNR065C
• Gene Name: YNR065C
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1116
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIPYDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKGTFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCGESDYECSFEFVRDANGLCIPDYNLIAFSNICDKSKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSSDREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPYFNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRTKAGVARFSSKLRARFGNRKGPTYSSLLQGQFSDESDGLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQPATSNIPDALPARSAIHKPDSTAVRNEDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	N-linked_Glycosylation	LTWRFVHNSSGLYAT EEEEEEECCCCEEEE	32.35	-
120	Phosphorylation	TTDSETNSITSLKGV ECCCCCCCCEEECCE	34.36	27017623
156	Ubiquitination	DWDLADGKCVNGAKY CCCCCCCCCCCCCCC	35.24	17644757
336	N-linked_Glycosylation	VVFNPYFNSSAYLFG EEECCCCCCCEEEEC	29.25	-
378	Ubiquitination	MPLDFSAKAQDTFIY CCCCCCHHHCCEEEE	45.44	17644757
389	Ubiquitination	TFIYYGGKNCESILS EEEEECCCCHHHHCC	54.80	17644757
407	Ubiquitination	HAVAYLTKDGGETFT CEEEEEECCCCCCHH	52.35	17644757
527	Ubiquitination	FTILGSEKGSIFLHL EEEECCCCCEEEEEE	60.70	17644757
549	Ubiquitination	HDFGNLLKSNSNGTS CCHHHHCCCCCCCCC	51.24	17644757
553	N-linked_Glycosylation	NLLKSNSNGTSFVTL HHCCCCCCCCCEEEE	63.11	-
586	Phosphorylation	GLEGIIITNIVSNRE CCEEEEEEECCCCHH	14.42	27214570
745	Ubiquitination	DYKFCGDKVLVKDII CCCCCCCEEEEEEEE	23.81	17644757
749	Ubiquitination	CGDKVLVKDIITVPR CCCEEEEEEEEEECC	38.76	17644757
829	Ubiquitination	FLRKTDEKCFIGNIP HHHHCCCCCEECCCC	36.94	23793018
846	N-linked_Glycosylation	EFSRNVKNCSCTRQD HHHCCCCCCCCCCCC	20.74	-
876	Phosphorylation	KLVKGLSSANGADIC EEEHHHHHCCCCHHC	30.69	27017623
892	Phosphorylation	KEPDLIEYYDSSGYR CCCCCEEEECCCCCC	12.94	28889911
893	Phosphorylation	EPDLIEYYDSSGYRK CCCCEEEECCCCCCE	9.14	28889911
898	Phosphorylation	EYYDSSGYRKIPLST EEECCCCCCEEEHHH	15.64	28889911
985	N-linked_Glycosylation	DDGLIENNRTDRVVN CCCCCCCCCHHHHHH	35.12	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YN94_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YN94_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YN94_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YDC1_YEAST	YDC1	physical	18467557
IMG2_YEAST	IMG2	genetic	27708008
SNF5_YEAST	SNF5	genetic	27708008
MTU1_YEAST	SLM3	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
EIF3J_YEAST	HCR1	genetic	27708008
BUL2_YEAST	BUL2	genetic	27708008
PKR1_YEAST	PKR1	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.