| UniProt ID | GPT_YEAST | |
|---|---|---|
| UniProt AC | P07286 | |
| Protein Name | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | |
| Gene Name | ALG7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 448 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein. |
|
| Protein Description | Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.. | |
| Protein Sequence | MLRLFSLALITCLIYYSKNQGPSALVAAVGFGIAGYLATDMLIPRVGKSFIKIGLFGKDLSKPGRPVLPETIGAIPAAVYLFVMFIYIPFIFYKYMVITTSGGGHRDVSVVEDNGMNSNIFPHDKLSEYLSAILCLESTVLLGIADDLFDLRWRHKFFLPAIAAIPLLMVYYVDFGVTHVLIPGFMERWLKKTSVDLGLWYYVYMASMAIFCPNSINILAGVNGLEVGQCIVLAILALLNDLLYFSMGPLATRDSHRFSAVLIIPFLGVSLALWKWNRWPATVFVGDTYCYFAGMVFAVVGILGHFSKTMLLLFIPQIVNFIYSCPQLFKLVPCPRHRLPKFNEKDGLMYPSRANLKEEPPKSIFKPILKLLYCLHLIDLEFDENNEIISTSNMTLINLTLVWFGPMREDKLCNTILKLQFCIGILALLGRHAIGAIIFGHDNLWTVR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 48 | Acetylation | MLIPRVGKSFIKIGL HHHHHCCCCCEEEEE | 39.06 | 25381059 | |
| 345 | Ubiquitination | RLPKFNEKDGLMYPS CCCCCCCCCCCCCCC | 59.19 | 23749301 | |
| 345 | Acetylation | RLPKFNEKDGLMYPS CCCCCCCCCCCCCCC | 59.19 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GPT_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GPT_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GPT_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PUR1_YEAST | ADE4 | physical | 18467557 | |
| RPB2_YEAST | RPB2 | physical | 18467557 | |
| GST1_YEAST | GTT1 | physical | 18719252 | |
| GAA1_YEAST | GAA1 | genetic | 20101242 | |
| VPS53_YEAST | VPS53 | genetic | 20101242 | |
| GAS1_YEAST | GAS1 | genetic | 20101242 | |
| EOS1_YEAST | EOS1 | genetic | 20101242 | |
| MET22_YEAST | MET22 | genetic | 20101242 | |
| CHO2_YEAST | CHO2 | genetic | 20101242 | |
| PHO88_YEAST | PHO88 | physical | 16093310 | |
| HMDH1_YEAST | HMG1 | physical | 16093310 | |
| ALG14_YEAST | ALG14 | physical | 19129246 | |
| GPT_YEAST | ALG7 | physical | 19129246 | |
| ALG13_YEAST | ALG13 | physical | 19129246 | |
| ALG14_YEAST | ALG14 | physical | 22061998 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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