HMS1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HMS1_YEAST
• UniProt AC: Q12398
• Protein Name: Probable transcription factor HMS1
• Gene Name: HMS1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 434
• Subcellular Localization: Nucleus .
• Protein Description: Involved in exit from mitosis and pseudohyphal differentiation..
• Protein Sequence: MPNFQKPFSGSSDGNSVMNDLGNKVAIKVFDCRSAQDGSEEQNVNVTTNQMYLMFQSNNYNVPPPNYNTEDLGSQGPPTHAYYAPFQHPIHLQPPVPPVYKNNTYSATDQYSDSSFPNTSGHTPVIDSNYYNDALASIPTTTTGSTTMTTDNGNTIDSEEYIDNMEVFSSEENENIDNVKQTDLKSEKDSSLLSAASIVKKEQLSGFENFLPLSKTESPLVTADEIKSSLNLENIDNADSMSFKLKTSPIRKHFHVKPKRITRVRTGRVSHNIIEKKYRSNINDKIEQLRRTVPTLRVAYKKCNDLPITSRDLADLDGLEPATKLNKASILTKSIEYICHLERKCLQLSLANQHLSNDTRDSFVHLTEPSQPLSDNSSSEQVQKQTRSCQRQRQRQPRQQQPLHNIQYNIPHQNGLMSGTNNSHDMDFNNAGDF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
190	Phosphorylation	DLKSEKDSSLLSAAS CCCCHHHHHHHHHHH	33.67	28889911
191	Phosphorylation	LKSEKDSSLLSAASI CCCHHHHHHHHHHHH	43.39	28889911
194	Phosphorylation	EKDSSLLSAASIVKK HHHHHHHHHHHHHHH	27.38	28889911
197	Phosphorylation	SSLLSAASIVKKEQL HHHHHHHHHHHHHHH	27.86	28889911
205	Phosphorylation	IVKKEQLSGFENFLP HHHHHHHCCCCCCCC	40.92	23607784
214	Phosphorylation	FENFLPLSKTESPLV CCCCCCCCCCCCCCC	35.28	23607784
215	Ubiquitination	ENFLPLSKTESPLVT CCCCCCCCCCCCCCC	65.09	19722269
216	Phosphorylation	NFLPLSKTESPLVTA CCCCCCCCCCCCCCH	38.02	24961812
218	Phosphorylation	LPLSKTESPLVTADE CCCCCCCCCCCCHHH	28.85	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HMS1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HMS1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HMS1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
H2AZ_YEAST	HTZ1	genetic	20959818
RRP6_YEAST	RRP6	genetic	20959818
SIN3_YEAST	SIN3	genetic	20959818
CG11_YEAST	CLN1	genetic	21127252
SIN3_YEAST	SIN3	genetic	21127252
CBF1_YEAST	CBF1	genetic	21127252
PHO80_YEAST	PHO80	genetic	21127252
IXR1_YEAST	IXR1	genetic	21127252
PDK1_YEAST	PKP1	genetic	21127252
KCC2_YEAST	CMK2	genetic	21127252
RSC2_YEAST	RSC2	genetic	21127252
BAS1_YEAST	BAS1	genetic	21127252
VPS71_YEAST	VPS71	genetic	21127252
SLT2_YEAST	SLT2	genetic	21127252
UME6_YEAST	UME6	genetic	21127252
PACC_YEAST	RIM101	genetic	21127252
CARA_YEAST	CPA1	genetic	24124444
CARB_YEAST	CPA2	genetic	24124444
PP2C1_YEAST	PTC1	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
UGA3_YEAST	UGA3	genetic	27708008
AIM7_YEAST	AIM7	genetic	27708008
TRM1_YEAST	TRM1	genetic	27708008
CEM1_YEAST	CEM1	genetic	27708008
HXKB_YEAST	HXK2	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
CBF1_YEAST	CBF1	genetic	27708008
SRL2_YEAST	SRL2	genetic	27708008
RS30A_YEAST	RPS30A	genetic	27708008
RS30B_YEAST	RPS30A	genetic	27708008
VRP1_YEAST	VRP1	genetic	27708008
ELP1_YEAST	IKI3	genetic	27708008
UBX2_YEAST	UBX2	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
BSC6_YEAST	BSC6	genetic	27708008
POC4_YEAST	POC4	genetic	27708008
CSG2_YEAST	CSG2	genetic	29674565
TPS2_YEAST	TPS2	genetic	29674565
SKY1_YEAST	SKY1	genetic	29674565
MED1_YEAST	MED1	genetic	29674565
RL40A_YEAST	RPL40B	genetic	29674565
RL40B_YEAST	RPL40B	genetic	29674565
ERG27_YEAST	ERG27	genetic	29674565

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.