MTND_YEAST - dbPTM
MTND_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MTND_YEAST
UniProt AC Q03677
Protein Name 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}
Gene Name ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 179
Subcellular Localization Cytoplasm. Nucleus.
Protein Description Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)..
Protein Sequence MVKVYIHDNKVDSDYRAPHNSGTELSLDELAKLGVIYKYCANEEEVNEIARQREYKNRDVVNICEGSFKSEAEFNEKLATFYQEHLHEDEEIRYCLEGAGYFDVRDASTPENWIRCLVESGDLLILPPGIYHRFTLTTSNHIKALRLFKDEPKWQAINRSNQADSLPVRKDYIALINQY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
67PhosphorylationVVNICEGSFKSEAEF
CHHCCCCCCCCHHHH
13.7530377154

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MTND_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MTND_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MTND_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CSG2_YEASTCSG2genetic
20093466
MBA1_YEASTMBA1genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
AFT1_YEASTAFT1genetic
20093466
PALF_YEASTRIM8genetic
20093466
ALG10_YEASTDIE2genetic
20093466
AIM18_YEASTAIM18genetic
20093466
PIR5_YEASTYJL160Cgenetic
20093466
PTK2_YEASTPTK2genetic
20093466
DCOR_YEASTSPE1genetic
20093466
NAP1_YEASTNAP1genetic
20093466
NU133_YEASTNUP133genetic
20093466
YL053_YEASTYLR053Cgenetic
20093466
SRN2_YEASTSRN2genetic
20093466
YL346_YEASTYLR346Cgenetic
20093466
PUR92_YEASTADE17genetic
20093466
BCH1_YEASTBCH1genetic
20093466
SPO1_YEASTSPO1genetic
20093466
SOL1_YEASTSOL1genetic
20093466
AGA1_YEASTAGA1genetic
20093466
SIL1_YEASTSIL1genetic
20093466
CSK22_YEASTCKA2genetic
20093466
DIA2_YEASTDIA2genetic
20093466
YO238_YEASTYOR238Wgenetic
20093466
YP109_YEASTYPL109Cgenetic
20093466
RAD1_YEASTRAD1genetic
20093466
SRO7_YEASTSRO7genetic
20093466
CSN12_YEASTYJR084Wgenetic
27708008
GEM1_YEASTGEM1genetic
27708008
CSG2_YEASTCSG2genetic
27708008
MBA1_YEASTMBA1genetic
27708008
ATG22_YEASTATG22genetic
27708008
IMG2_YEASTIMG2genetic
27708008
NHP10_YEASTNHP10genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
OMS1_YEASTOMS1genetic
27708008
GET2_YEASTGET2genetic
27708008
PALF_YEASTRIM8genetic
27708008
MPC1_YEASTMPC1genetic
27708008
MRM2_YEASTMRM2genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
ENV11_YEASTENV11genetic
27708008
ASK10_YEASTASK10genetic
27708008
HSE1_YEASTHSE1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
ICE2_YEASTICE2genetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
CYP7_YEASTCPR7genetic
27708008
FRA1_YEASTFRA1genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
SRN2_YEASTSRN2genetic
27708008
YL346_YEASTYLR346Cgenetic
27708008
ATP10_YEASTATP10genetic
27708008
MDM1_YEASTMDM1genetic
27708008
CTK3_YEASTCTK3genetic
27708008
HUB1_YEASTHUB1genetic
27708008
SOL1_YEASTSOL1genetic
27708008
SIL1_YEASTSIL1genetic
27708008
INO4_YEASTINO4genetic
27708008
CSK22_YEASTCKA2genetic
27708008
DIA2_YEASTDIA2genetic
27708008
WHI5_YEASTWHI5genetic
27708008
YO105_YEASTYOR105Wgenetic
27708008
MCP1_YEASTMCP1genetic
27708008
PHSG_YEASTGPH1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MTND_YEAST

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Related Literatures of Post-Translational Modification

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