AST1_YEAST - dbPTM
AST1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AST1_YEAST
UniProt AC P35183
Protein Name Protein AST1
Gene Name AST1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 429
Subcellular Localization Membrane
Peripheral membrane protein.
Protein Description Reroutes mutant ATPase from the vacuole to the cell surface. Participates in membrane traffic. Interacts with PMA1..
Protein Sequence MAKDILKNQDPKLQAMIVEHSAPAPKEIPMDAPVLKRVARPLRHVKFIPIKSLIFHTKTGPMDFSYEKKIKTPIPKNKIVVRVSNVGLNPVDMKIRNGYTSSIYGEIGLGREYSGVITEVGENLNYAWHVGDEVYGIYYHPHLAVGCLQSSILVDPKVDPILLRPESVSAEEAAGSLFCLATGYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQLLKRHYKLQKKLVIVTSANGPQVLQEKFPDLADEMIFIDYLTCRGKSSKPLRKMLEEKKISQYDPVEDKETILNYNEGKFDVVLDFVGGYDILSHSSSLIHGGGAYVTTVGDYVANYKEDIFDSWDNPSANARKMFGSIIWSYNYTHYYFDPNAKTASANNDWIEQCGDFLKNGTVKCVVDKVYDWKDHKEAFSYMATQRAQGKLIMNVEKF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Acetylation-MAKDILKNQDPKLQ
-CHHHHHHCCCHHHH		53.5525381059
12UbiquitinationILKNQDPKLQAMIVE
HHHCCCHHHHHEEEE		62.6124961812
12AcetylationILKNQDPKLQAMIVE
HHHCCCHHHHHEEEE		62.6124489116
36AcetylationPMDAPVLKRVARPLR
CCCHHHHHHHHHCCC		45.0925381059
94UbiquitinationGLNPVDMKIRNGYTS
CCCCCCEEECCCCCC		33.7723749301
359PhosphorylationMFGSIIWSYNYTHYY
HHHHHHHEEECCEEE		7.9730377154
362PhosphorylationSIIWSYNYTHYYFDP
HHHHEEECCEEEECC		6.1530377154
365PhosphorylationWSYNYTHYYFDPNAK
HEEECCEEEECCCCC		9.6830377154
366PhosphorylationSYNYTHYYFDPNAKT
EEECCEEEECCCCCC		8.2330377154
394UbiquitinationFLKNGTVKCVVDKVY
HHHCCEEEEEEEEEC		22.5823749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AST1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AST1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AST1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TVP15_YEASTTVP15physical
18719252
GPR1_YEASTGPR1genetic
27708008
VPS41_YEASTVPS41genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
GUF1_YEASTGUF1genetic
27708008
SWC7_YEASTSWC7genetic
27708008
SLK19_YEASTSLK19genetic
27708008
TAH1_YEASTTAH1genetic
27708008
ATG9_YEASTATG9genetic
27708008
ODO2_YEASTKGD2genetic
27708008
SAC3_YEASTSAC3genetic
27708008
CEM1_YEASTCEM1genetic
27708008
TBP7_YEASTYTA7genetic
27708008
SLH1_YEASTSLH1genetic
27708008
FMC1_YEASTFMC1genetic
27708008
LPLA_YEASTAIM22genetic
27708008
IF4A_YEASTTIF2genetic
27708008
AIM24_YEASTAIM24genetic
27708008
DPH4_YEASTJJJ3genetic
27708008
DHOM_YEASTHOM6genetic
27708008
FABG_YEASTOAR1genetic
27708008
PRY2_YEASTPRY2genetic
27708008
YPT6_YEASTYPT6genetic
27708008
ATP10_YEASTATP10genetic
27708008
PALI_YEASTRIM9genetic
27708008
YNE0_YEASTYNL040Wgenetic
27708008
COQ2_YEASTCOQ2genetic
27708008
SEY1_YEASTSEY1genetic
27708008
MTHR1_YEASTMET12genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
PHSG_YEASTGPH1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AST1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory