YL224_YEAST - dbPTM
YL224_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YL224_YEAST
UniProt AC Q05947
Protein Name F-box protein YLR224W
Gene Name YLR224W
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 369
Subcellular Localization
Protein Description Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity)..
Protein Sequence MNQSDSSLMDLPLEIHLSLLEYVPNELRAVNKYFYVLHNHSYKEKSLAWIAEDNYIWAVVKHSLCLYVKSLDPLRQHAREIIQETKEPGFNVPLCMTKYIADSWYIVYNALQYPGKIINMGWDKYTKSQDSNGSDSTSNFNSRPKERTLMQSLTALPVNFWSRRKDEPTPVNVWFYVKNAHVARYIPKIITEIGICNYGPKQIVASAGYINELITSEGIYCVNLGHLPRLYDEQIFEGTGTTHLPLELKAIDRTDSDVCINGDLVLLGYDFIPYQISKPWLLFRIEPVNSIEAIFNYSECSFSYQFAWSLACLQSEEKISFPRDTIIGHGLPYKPSKLIRIFVYKHPEQKQDLGQEIALPNWNTPYLRR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of YL224_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YL224_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YL224_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YL224_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YL224_YEASTYLR224Wphysical
14747994
ENO2_YEASTENO2physical
26297823
IES1_YEASTIES1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
RTG1_YEASTRTG1genetic
27708008
NIP80_YEASTNIP100genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
SGF29_YEASTSGF29genetic
27708008
CRD1_YEASTCRD1genetic
27708008
PMP3_YEASTPMP3genetic
27708008
EF2_YEASTEFT2genetic
27708008
SNF1_YEASTSNF1genetic
27708008
UBP3_YEASTUBP3genetic
27708008
CSK2B_YEASTCKB1genetic
27708008
AAKG_YEASTSNF4genetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
MED20_YEASTSRB2genetic
27708008
RS21B_YEASTRPS21Bgenetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
SDHB_YEASTSDH2genetic
27708008
BRE2_YEASTBRE2genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
DCR2_YEASTDCR2genetic
27708008
VID22_YEASTVID22genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
ERG5_YEASTERG5genetic
27708008
ELP6_YEASTELP6genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
ATP23_YEASTATP23genetic
27708008
SDHF2_YEASTSDH5genetic
27708008
CSK2C_YEASTCKB2genetic
27708008
VAM3_YEASTVAM3genetic
27708008
PALA_YEASTRIM20genetic
27708008
PDE2_YEASTPDE2genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
CSR2_YEASTCSR2genetic
27708008
CISY2_YEASTCIT2physical
27697924
CLK2_HUMANCLK2physical
27107014
ACS1_YEASTACS1genetic
29674565
PEX22_YEASTPEX22genetic
29674565
SLA1_YEASTSLA1genetic
29674565
CND2_YEASTBRN1genetic
29674565
CSG2_YEASTCSG2genetic
29674565
MAK5_YEASTMAK5genetic
29674565
HAL4_YEASTSAT4genetic
29674565
SNT1_YEASTSNT1genetic
29674565
VAM6_YEASTVAM6genetic
29674565
GET3_YEASTGET3genetic
29674565
DPOD_YEASTPOL3genetic
29674565
DAD1_YEASTDAD1genetic
29674565
ARX1_YEASTARX1genetic
29674565
RM01_YEASTMRPL1genetic
29674565
SAC3_YEASTSAC3genetic
29674565
CDC1_YEASTCDC1genetic
29674565
H2A1_YEASTHTA1genetic
29674565
KRE28_YEASTKRE28genetic
29674565
CEM1_YEASTCEM1genetic
29674565
GET2_YEASTGET2genetic
29674565
SWI4_YEASTSWI4genetic
29674565
ODPA_YEASTPDA1genetic
29674565
GET1_YEASTGET1genetic
29674565
NBP35_YEASTNBP35genetic
29674565
RTF1_YEASTRTF1genetic
29674565
RTG2_YEASTRTG2genetic
29674565
SLX9_YEASTSLX9genetic
29674565
CHO2_YEASTCHO2genetic
29674565
OPI1_YEASTOPI1genetic
29674565
ICE2_YEASTICE2genetic
29674565
PRI1_YEASTPRI1genetic
29674565
SYS1_YEASTSYS1genetic
29674565
RS21B_YEASTRPS21Bgenetic
29674565
RPA34_YEASTRPA34genetic
29674565
PRP21_YEASTPRP21genetic
29674565
CBF1_YEASTCBF1genetic
29674565
FRMSR_YEASTYKL069Wgenetic
29674565
PRS7_YEASTRPT1genetic
29674565
SDHA_YEASTSDH1genetic
29674565
SAC1_YEASTSAC1genetic
29674565
POC3_YEASTIRC25genetic
29674565
RIC1_YEASTRIC1genetic
29674565
RS3A1_YEASTRPS1Agenetic
29674565
SCS7_YEASTSCS7genetic
29674565
LST8_YEASTLST8genetic
29674565
ODP2_YEASTLAT1genetic
29674565
BUB3_YEASTBUB3genetic
29674565
CHL1_YEASTCHL1genetic
29674565
LGE1_YEASTLGE1genetic
29674565
GGPPS_YEASTBTS1genetic
29674565
HSP7F_YEASTSSE1genetic
29674565
NCBP2_YEASTCBC2genetic
29674565
AP3D_YEASTAPL5genetic
29674565
RU2A_YEASTLEA1genetic
29674565
NEW1_YEASTNEW1genetic
29674565
YAR1_YEASTYAR1genetic
29674565
BRR1_YEASTBRR1genetic
29674565
MED1_YEASTMED1genetic
29674565
WDR59_YEASTMTC5genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YL224_YEAST

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Related Literatures of Post-Translational Modification

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