BMT5_YEAST - dbPTM
BMT5_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BMT5_YEAST
UniProt AC P40493
Protein Name 25S rRNA (uridine(2634)-N(3))-methyltransferase
Gene Name BMT5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 336
Subcellular Localization Nucleus, nucleolus .
Protein Description S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2634 (m3U2634) in 25S rRNA..
Protein Sequence MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEKDETLMLCGEGDFSFARSIVEQNYIESDNLIITSYDNSVNELKLKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGKGIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQGYDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSEQDTTKPAKERDARFYIFSKYVSNSSKHNRKSKKDTDSDSD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
12AcetylationLKGKIGSKGLKGALL
CCCCCCCCCHHHHHH		25381059
15AcetylationKIGSKGLKGALLRHK
CCCCCCHHHHHHHHH		25381059
59AcetylationKRNQEFQKLNQGKVM
HHHHHHHHHHCCCCC		24489116
186AcetylationPHNGKGIKDQERNIR
CCCCCCCCHHHHHHH		25381059
322AcetylationKYVSNSSKHNRKSKK
HHCCCCCCCCCCCCC		25381059
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BMT5_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BMT5_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BMT5_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CLC1_YEASTCLC1physical
16554755
NMD4_YEASTNMD4genetic
19061648
NRP1_YEASTNRP1genetic
19061648
LSM1_YEASTLSM1genetic
19061648
UTP18_YEASTUTP18genetic
19061648
LTV1_YEASTLTV1genetic
19061648
BMT6_YEASTBMT6genetic
24335083
IES1_YEASTIES1genetic
27708008
MON1_YEASTMON1genetic
27708008
DBF2_YEASTDBF2genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
EF1G2_YEASTTEF4genetic
27708008
PFD4_YEASTGIM3genetic
27708008
KIN4_YEASTKIN4genetic
27708008
RL36A_YEASTRPL36Agenetic
29158977
DOM34_YEASTDOM34genetic
29158977
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BMT5_YEAST

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Related Literatures of Post-Translational Modification

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