| UniProt ID | BMT6_YEAST | |
|---|---|---|
| UniProt AC | Q12291 | |
| Protein Name | 25S rRNA (uridine(2843)-N(3))-methyltransferase | |
| Gene Name | BMT6 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 365 | |
| Subcellular Localization | Cytoplasm . Nucleus . Localizes predominantly to the cytoplasm, with minor localizations in the nucleus (PubMed:24335083). Associates with pre-60S ribosomal particles (PubMed:24335083). | |
| Protein Description | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2843 (m3U2843) in 25S rRNA.. | |
| Protein Sequence | MLLMRRFAFLTSSVYFKYIPIYSQYHYSSQFPINMNPKKVAQLPVHNKSTLPPQEIIDLFKITFLEELYPKDQDNEKSPLTEQIQAVKSDLYNRDYNAAFNNDSKRIAYCCRWSPSRATSYASVFAHFPELLKIIRCEIDDKDSNVLCIGGGAGGELVALASIFTLSRDFSSKFASALKIDNEVNKKPRNLNIQLVDIADWSTVVEKLTATIKSKWLYGDSEAESFNVNFTHKDCLQMTEPQDIKIYQGLDLITLLFTTNELFTQKKVESIKFLQRLNENCAPGCHLLILESAGSYSHITINNKKFPIQFLIDTILVGNRKDKGTTGPWSLVSENDSIWYRMDPKLDYSIPLENMRFFYRLYVKN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 15 | Phosphorylation | AFLTSSVYFKYIPIY HHHHHCEEHHCCCCC | 28132839 | ||
| 78 | Phosphorylation | KDQDNEKSPLTEQIQ CCCCCCCCCHHHHHH | 23749301 | ||
| 173 | Acetylation | LSRDFSSKFASALKI CCCCCHHHHHHHHHC | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BMT6_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BMT6_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BMT6_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NOP2_YEAST | NOP2 | physical | 24335083 | |
| SLX5_YEAST | SLX5 | genetic | 27708008 | |
| YD249_YEAST | YDR249C | genetic | 27708008 | |
| RAD4_YEAST | RAD4 | genetic | 27708008 | |
| PIR1_YEAST | PIR1 | genetic | 27708008 | |
| RTG1_YEAST | RTG1 | genetic | 27708008 | |
| BRR1_YEAST | BRR1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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