YPT35_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YPT35_YEAST
• UniProt AC: P38815
• Protein Name: PX domain-containing protein YPT35
• Gene Name: YPT35
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 214
• Subcellular Localization: Endosome membrane ; Peripheral membrane protein .
• Protein Sequence: MSDKISFLPPEPIQLLDEDSTEPELDIDSQQENEGPISASNSNDSTSHSNDCGATITRTRPRRSSSINANFSFQKAHVSDCTIVNGDHGTKFAVWRITVFLEPNLKAFAAKRESYKIQTYKRYSDFVRLRENLLTRIKTAKPEKLNCLQIPHLPPSVQWYSSWKYQEVNLNKDWLAKRQRGLEYFLNHIILNSSLVEMTKDILIQFLEPSKRVA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Phosphorylation	TRTRPRRSSSINANF EECCCCCCCCCCCCC	29.71	19684113
65	Phosphorylation	RTRPRRSSSINANFS ECCCCCCCCCCCCCE	33.16	19684113
66	Phosphorylation	TRPRRSSSINANFSF CCCCCCCCCCCCCEE	22.55	19684113

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YPT35_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YPT35_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YPT35_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS13_YEAST	VPS13	physical	11805837
AKR2_YEAST	AKR2	physical	10688190
KTR3_YEAST	KTR3	physical	10688190
YIP5_YEAST	YIP5	physical	10688190
YIF1_YEAST	YIF1	physical	10688190
RBD2_YEAST	RBD2	physical	10688190
AKR2_YEAST	AKR2	physical	15263065
ATR1_YEAST	ATR1	physical	15263065
BET1_YEAST	BET1	physical	15263065
BOS1_YEAST	BOS1	physical	15263065
KTR3_YEAST	KTR3	physical	15263065
PEP12_YEAST	PEP12	physical	15263065
RBD2_YEAST	RBD2	physical	15263065
SPS18_YEAST	SPS18	physical	15263065
TVP23_YEAST	TVP23	physical	15263065
YIF1_YEAST	YIF1	physical	15263065
YIP1_YEAST	YIP1	physical	15263065
YIP4_YEAST	YIP4	physical	15263065
YIP5_YEAST	YIP5	physical	15263065
YMD8_YEAST	YMD8	physical	15263065
YO292_YEAST	YOR292C	physical	15263065
TVP15_YEAST	TVP15	physical	18719252
PRA1_YEAST	YIP3	physical	18719252
PRAF1_HUMAN	RABAC1	physical	27107014
CACO2_HUMAN	CALCOCO2	physical	27107014
ATRAP_HUMAN	AGTRAP	physical	27107014
TM239_HUMAN	TMEM239	physical	27107014
REEP6_HUMAN	REEP6	physical	27107014

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.