SIT1_YEAST - dbPTM
SIT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SIT1_YEAST
UniProt AC P39980
Protein Name Siderophore iron transporter 1
Gene Name SIT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 628
Subcellular Localization Endosome membrane
Multi-pass membrane protein .
Protein Description Involved in the transport of siderophore ferrioxamine B and so has a role in iron homeostasis..
Protein Sequence MDPGIANHTLPEEFEEVVVPEMLEKEVGAKVDVKPTLTTSSPAPSYIELIDPGVHNIEIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNCIKTVIAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGLTGIILILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAIDANWKWGIGMWAFILPLACIPLGICMLHMRYLARKHAKDRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLLITVFFGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQDRGIFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILGFILIKVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQASIQASAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAYGSPFTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTDSIALEGNDHLESKNTFEIEEKEESFLKNKFFTHFTSSKDRKD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41PhosphorylationKPTLTTSSPAPSYIE
CCCCCCCCCCCCEEE		24.0027214570
607UbiquitinationNTFEIEEKEESFLKN
CEEEEHHHHHHHHHH		54.7323793018
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SIT1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SIT1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SED1_YEASTSED1physical
15611868
FET3_YEASTFET3genetic
10744769
TFS2_YEASTDST1genetic
9573141
AFT1_YEASTAFT1physical
19469713
AFT1_YEASTAFT1genetic
19469713
BDH1_YEASTBDH1genetic
20093466
SSF2_YEASTSSF2genetic
20093466
MED5_YEASTNUT1genetic
20093466
SUN4_YEASTSUN4genetic
20093466
SFL1_YEASTSFL1genetic
20093466
VPS27_YEASTVPS27genetic
20526336
MED8_YEASTMED8genetic
27708008
TCPD_YEASTCCT4genetic
27708008
FAL1_YEASTFAL1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SAD1_YEASTSAD1genetic
27708008
PSA1_YEASTSCL1genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
POB3_YEASTPOB3genetic
27708008
SYH_YEASTHTS1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
SEC23_YEASTSEC23genetic
27708008
BDH1_YEASTBDH1genetic
27708008
SSF2_YEASTSSF2genetic
27708008
MED5_YEASTNUT1genetic
27708008
SUN4_YEASTSUN4genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SIT1_YEAST

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Related Literatures of Post-Translational Modification

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