COQ4_YEAST - dbPTM
COQ4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COQ4_YEAST
UniProt AC O13525
Protein Name Ubiquinone biosynthesis protein COQ4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111}
Gene Name COQ4 {ECO:0000255|HAMAP-Rule:MF_03111}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 335
Subcellular Localization Mitochondrion inner membrane
Peripheral membrane protein
Matrix side .
Protein Description Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides..
Protein Sequence MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLADAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAISGWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMDKLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITNMPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSCKPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTPA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
161AcetylationTEILHMDKLAKLPHN
CEEEEHHHHHCCCCC
42.6524489116
192UbiquitinationPDTRAPVKFIDDPMH
CCCCCCCEECCCHHH
35.2324961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COQ4_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COQ4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COQ4_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NDI1_YEASTNDI1genetic
23116202
NDH1_YEASTNDE1genetic
23116202
COQ9_YEASTCOQ9physical
24406904
COQ8_YEASTCOQ8genetic
24406904
GLE1_YEASTGLE1genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
KTHY_YEASTCDC8genetic
27708008
HIR1_YEASTHIR1genetic
27708008
ATG15_YEASTATG15genetic
27708008
ATC5_YEASTDNF1genetic
27708008
INM1_YEASTINM1genetic
27708008
POM33_YEASTPOM33genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
IPA3_YEASTPAI3genetic
27708008
PET8_YEASTPET8genetic
27708008
SEC17_YEASTSEC17genetic
27708008
POP7_YEASTPOP7genetic
27708008
MED8_YEASTMED8genetic
27708008
TAF5_YEASTTAF5genetic
27708008
MPS1_YEASTMPS1genetic
27708008
TIM22_YEASTTIM22genetic
27708008
RSP5_YEASTRSP5genetic
27708008
CCA1_YEASTCCA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
RNA15_YEASTRNA15genetic
27708008
PRP31_YEASTPRP31genetic
27708008
SYMC_YEASTMES1genetic
27708008
SLN1_YEASTSLN1genetic
27708008
TAD2_YEASTTAD2genetic
27708008
TIM16_YEASTPAM16genetic
27708008
CDC11_YEASTCDC11genetic
27708008
YKT6_YEASTYKT6genetic
27708008
SSL1_YEASTSSL1genetic
27708008
BOS1_YEASTBOS1genetic
27708008
ERG27_YEASTERG27genetic
27708008
RU1C_YEASTYHC1genetic
27708008
TAF13_YEASTTAF13genetic
27708008
ARP9_YEASTARP9genetic
27708008
MED11_YEASTMED11genetic
27708008
VTI1_YEASTVTI1genetic
27708008
LST8_YEASTLST8genetic
27708008
MED7_YEASTMED7genetic
27708008
RPB2_YEASTRPB2genetic
27708008
SYQ_YEASTGLN4genetic
27708008
PRS10_YEASTRPT4genetic
27708008
GPN2_YEASTGPN2genetic
27708008
TFC8_YEASTTFC8genetic
27708008
COPZ_YEASTRET3genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
MMS2_YEASTMMS2genetic
27708008
YGZ2_YEASTYGL242Cgenetic
27708008
ADH4_YEASTADH4genetic
27708008
OPI1_YEASTOPI1genetic
27708008
IGO2_YEASTIGO2genetic
27708008
YHY2_YEASTYHR182Wgenetic
27708008
MNL1_YEASTMNL1genetic
27708008
ATG32_YEASTATG32genetic
27708008
YJ24_YEASTKCH1genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
ATP23_YEASTATP23genetic
27708008
YO087_YEASTDUF1genetic
27708008
CSK22_YEASTCKA2genetic
27708008
PMA2_YEASTPMA2genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
THI22_YEASTTHI22genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COQ4_YEAST

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Related Literatures of Post-Translational Modification

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