AFG1_YEAST - dbPTM
AFG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AFG1_YEAST
UniProt AC P32317
Protein Name Protein AFG1
Gene Name AFG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 509
Subcellular Localization
Protein Description
Protein Sequence MIALKPNAVRTFRQVQHCSFRICRYQSTKSNKCLTPLQEYDRLVKLGKLRDDTYQRGIISSLGDLYDSLVKYVPPVVKTPNAVDQVGGWLNGLKSVFSRGKPKNIGAYVDVSKIGNSIPRGVYLYGDVGCGKTMLMDLFYTTIPNHLTKKRIHFHQFMQYVHKRSHEIVREQNLKELGDAKGKEIDTVPFLAAEIANNSHVLCFDEFQVTDVADAMILRRLMTALLSDDYGVVLFATSNRHPDELYINGVQRQSFIPCIELIKHRTKVIFLNSPTDYRKIPRPVSSVYYFPSDTSIKYASKECKTRRETHIKEWYNYFAQASHTDDSTDSHTVHKTFYDYPLTIWGREFKVPKCTPPRVAQFTFKQLCGEPLAAGDYLTLAKNFEAFIVTDIPYLSIYVRDEVRRFITFLDAVYDSGGKLATTGAADFSSLFVEPEQILNDFELRPTTKEPDSVDTGMVDEMVEKHGFSKEIAKKSQMFALDEERFAFARALSRLSQMSSTDWVTKPTY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
133PhosphorylationGDVGCGKTMLMDLFY
CCCCCCHHHHHHHHH		10.7927017623
140PhosphorylationTMLMDLFYTTIPNHL
HHHHHHHHHCCCCCC		15.4027017623
141PhosphorylationMLMDLFYTTIPNHLT
HHHHHHHHCCCCCCC		15.7727017623
286PhosphorylationKIPRPVSSVYYFPSD
CCCCCCCEEEEECCC		17.8630377154
288PhosphorylationPRPVSSVYYFPSDTS
CCCCCEEEEECCCCH		11.0130377154
289PhosphorylationRPVSSVYYFPSDTSI
CCCCEEEEECCCCHH		13.5830377154
295PhosphorylationYYFPSDTSIKYASKE
EEECCCCHHHHCCHH		23.2930377154
377PhosphorylationEPLAAGDYLTLAKNF
CCCCCCCHHHHHHCC		10.7319684113
453PhosphorylationPTTKEPDSVDTGMVD
CCCCCCCCCCCCHHH		32.3828889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AFG1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AFG1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AFG1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AFG1_YEASTAFG1physical
22940862
VPH1_YEASTVPH1genetic
27708008
AGP1_YEASTAGP1genetic
27708008
SNQ2_YEASTSNQ2genetic
27708008
MED5_YEASTNUT1genetic
27708008
MDV1_YEASTMDV1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
DIC1_YEASTDIC1genetic
27708008
ELO3_YEASTELO3genetic
27708008
VID22_YEASTVID22genetic
27708008
PYRE_YEASTURA5genetic
27708008
MSC1_YEASTMSC1genetic
27708008
MTND_YEASTADI1genetic
27708008
RCO1_YEASTRCO1genetic
27708008
MGR3_YEASTMGR3genetic
27708008
PKR1_YEASTPKR1genetic
27708008
TPP1_YEASTTPP1genetic
27708008
HDA1_YEASTHDA1genetic
27708008
NST1_YEASTNST1genetic
27708008
RSB1_YEASTRSB1genetic
27708008
YO105_YEASTYOR105Wgenetic
27708008
KIN4_YEASTKIN4genetic
27708008
NACB1_YEASTEGD1genetic
27708008
LGE1_YEASTLGE1genetic
27708008
SUR1_YEASTSUR1genetic
27708008
TGS1_YEASTTGS1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
NEW1_YEASTNEW1genetic
27708008
YP260_YEASTYPL260Wgenetic
27708008
YMC1_YEASTYMC1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
MED1_YEASTMED1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AFG1_YEAST

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Related Literatures of Post-Translational Modification

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