dbPTM

SCS22_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SCS22_YEAST
UniProt AC	Q6Q595
Protein Name	Vesicle-associated membrane protein-associated protein SCS22
Gene Name	SCS22
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	175
Subcellular Localization	Membrane Single-pass type IV membrane protein .
Protein Description	Targets proteins containing a FFAT motif to membranes (By similarity). Involved in regulation of phospholipid metabolism..
Protein Sequence	MRIVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVEDGELLSDWPNLEEQYKDDIVFKKIKIFHSVLPKRKPSGNHDAESARAPSAGNGQSLSSRALLIITVIALLVGWIYY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Acetylation	-MRIVPEKLVFKAPL -CCCCCCCEEEECCC	43.83	24489116
124	Acetylation	DIVFKKIKIFHSVLP CCHHEEEEEHHHCCC	48.47	24489116
136	Phosphorylation	VLPKRKPSGNHDAES CCCCCCCCCCCCHHH	56.09	30377154

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SCS22_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SCS22_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SCS22_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GST1_YEAST	GTT1	physical	18719252
PEX29_YEAST	PEX29	physical	18719252
SEC62_YEAST	SEC62	physical	18719252
USA1_YEAST	USA1	physical	18719252
PALH_YEAST	RIM21	genetic	27803246
YO024_YEAST	YOL024W	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
YO059_YEAST	LPL1	genetic	27708008
GYP1_YEAST	GYP1	genetic	27708008
GET4_YEAST	GET4	genetic	27708008
PFF1_YEAST	PFF1	genetic	27708008
PAT1_YEAST	PAT1	genetic	27708008
ARO1_YEAST	ARO1	genetic	27708008
BMH1_YEAST	BMH1	genetic	27708008
CYP7_YEAST	CPR7	genetic	27708008
MEH1_YEAST	MEH1	genetic	27708008
OAF3_YEAST	OAF3	genetic	27708008
AIM29_YEAST	AIM29	genetic	27708008
ELO3_YEAST	ELO3	genetic	27708008
GSF2_YEAST	GSF2	genetic	27708008
ARE2_YEAST	ARE2	genetic	27708008
BRE5_YEAST	BRE5	genetic	27708008
MNT4_YEAST	MNT4	genetic	27708008
PHO80_YEAST	PHO80	genetic	27708008
YO014_YEAST	YOL014W	genetic	27708008
PHM7_YEAST	PHM7	genetic	27708008
YO114_YEAST	YOL114C	genetic	27708008
HPF1_YEAST	HPF1	genetic	27708008
RRP6_YEAST	RRP6	genetic	27708008
CSK22_YEAST	CKA2	genetic	27708008
THI72_YEAST	THI72	genetic	27708008
KASH5_HUMAN	CCDC155	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SCS22_YEAST

Related Literatures of Post-Translational Modification