YEF1_YEAST - dbPTM
YEF1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YEF1_YEAST
UniProt AC P32622
Protein Name ATP-NADH kinase YEF1
Gene Name YEF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 495
Subcellular Localization
Protein Description ATP-NADH kinase with a low phosphorylation activity of both NADH and NAD(+) to produce NADP and NADPH by using ATP. UTR1 is responsible for essentially all of the NAD/NADH kinase activity resident in the cytoplasm, whereas POS5 is responsible for all mitochondrial NAD/NADH kinase activity and consequent mitochondrial genome maintenance. YEF1 can substitute for UTR1 when overexpressed..
Protein Sequence MKTDRLLINASPETCTKGDAEMDTMDTIDRMTSVKVLAEGKVLSNFEEPGLMRCGYHDAKNWVRRLSSETIVGEDTSNLYPFYVDTAYDVRRLRKDLINAKVDLQVENLIIICNINDISTVFLMREVVEWILRNFHSITVYVQDIFKKSTQFAVGDLCKDSNCSKNRVKYWSKEFVKKHDSFFDLMITLGGDGTVLFASSIFTKDVPPIVPFALGSLGFLTNFEFQNFKETLKHILTDEVRINLRMRLQCKLYRRNKPEIDAATGRKICYIDFISEHHVLNEVTIDRGPAPCLSLLELYGNDSLMTKVQGDGLIVATPTGSTAYSLSAGGSLISPSVNAIAVTPICPHTLSFRPIILPDSMELKVRVDMNSRGTSWVNFDGKDRVELKQGDYVVITASPYSVPTIESSASEFFESISKNLNWNDREEQKPFAHILSPKNQEKYRLDSSKNGNDTISNPLESSCISSDAQDEERKSVTETETEIVVERTRQAHFAI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationDRLLINASPETCTKG
CEEEECCCCCCCCCC		20.8421551504
16PhosphorylationNASPETCTKGDAEMD
CCCCCCCCCCCCCCC		45.5428889911
32PhosphorylationMDTIDRMTSVKVLAE
CHHHHHHHHCEEEEC		31.1221440633
67PhosphorylationKNWVRRLSSETIVGE
HHHHHHHCCCEEECC		25.0722369663
68PhosphorylationNWVRRLSSETIVGED
HHHHHHCCCEEECCC		43.2722369663
70PhosphorylationVRRLSSETIVGEDTS
HHHHCCCEEECCCCC		23.9419779198
76PhosphorylationETIVGEDTSNLYPFY
CEEECCCCCCCCCEE		18.4019779198
119PhosphorylationICNINDISTVFLMRE
EEECCCCHHHHHHHH		22.7525371407
120PhosphorylationCNINDISTVFLMREV
EECCCCHHHHHHHHH		18.6625371407
436PhosphorylationKPFAHILSPKNQEKY
CCCCEEECCCCHHHH		32.9728889911
475PhosphorylationAQDEERKSVTETETE
CCHHHHHCCCCCCCH		40.2628889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YEF1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YEF1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YEF1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UTR1_YEASTUTR1physical
11283351
URE2_YEASTURE2physical
18467557
RL4A_YEASTRPL4Aphysical
22940862
HSP72_YEASTSSA2physical
22940862
CAF17_YEASTIBA57physical
22940862
SSB1_YEASTSSB1physical
22940862
HSP71_YEASTSSA1physical
22940862
DED1_YEASTDED1physical
22940862
RS17B_YEASTRPS17Bphysical
22940862
CSN12_YEASTYJR084Wgenetic
27708008
PET8_YEASTPET8genetic
27708008
YME1_YEASTYME1genetic
27708008
APC11_YEASTAPC11genetic
27708008
CDC53_YEASTCDC53genetic
27708008
FAL1_YEASTFAL1genetic
27708008
MAK21_YEASTMAK21genetic
27708008
ACT_YEASTACT1genetic
27708008
FIP1_YEASTFIP1genetic
27708008
TAD3_YEASTTAD3genetic
27708008
RNA1_YEASTRNA1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
DCP2_YEASTDCP2genetic
27708008
DEP1_YEASTDEP1genetic
27708008
SAW1_YEASTSAW1genetic
27708008
DHE5_YEASTGDH3genetic
27708008
ACH1_YEASTACH1genetic
27708008
YBC8_YEASTYBL028Cgenetic
27708008
YBQ3_YEASTYBR053Cgenetic
27708008
RU1A_YEASTMUD1genetic
27708008
MSI1_YEASTMSI1genetic
27708008
TYDP1_YEASTTDP1genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
SLX5_YEASTSLX5genetic
27708008
UBX3_YEASTUBX3genetic
27708008
FADH_YEASTSFA1genetic
27708008
RL41A_YEASTRPL41Agenetic
27708008
RL41B_YEASTRPL41Agenetic
27708008
ARX1_YEASTARX1genetic
27708008
SWM1_YEASTSWM1genetic
27708008
XRS2_YEASTXRS2genetic
27708008
ODPA_YEASTPDA1genetic
27708008
PALF_YEASTRIM8genetic
27708008
RL9A_YEASTRPL9Agenetic
27708008
EFM5_YEASTAML1genetic
27708008
AZR1_YEASTAZR1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
BZZ1_YEASTBZZ1genetic
27708008
SIM1_YEASTSIM1genetic
27708008
NTA1_YEASTNTA1genetic
27708008
YJ9K_YEASTYJR146Wgenetic
27708008
BYE1_YEASTBYE1genetic
27708008
YKH5_YEASTYKL075Cgenetic
27708008
DCOR_YEASTSPE1genetic
27708008
MEH1_YEASTMEH1genetic
27708008
FOX2_YEASTFOX2genetic
27708008
YK58_YEASTYKR078Wgenetic
27708008
FLO10_YEASTFLO10genetic
27708008
COX12_YEASTCOX12genetic
27708008
SRL2_YEASTSRL2genetic
27708008
YL126_YEASTYLR126Cgenetic
27708008
PEX13_YEASTPEX13genetic
27708008
STE23_YEASTSTE23genetic
27708008
YL407_YEASTYLR407Wgenetic
27708008
TBA3_YEASTTUB3genetic
27708008
HFD1_YEASTHFD1genetic
27708008
YM01_YEASTYMR111Cgenetic
27708008
MSS11_YEASTMSS11genetic
27708008
CG11_YEASTCLN1genetic
27708008
BUL1_YEASTBUL1genetic
27708008
CBPY_YEASTPRC1genetic
27708008
DCAM_YEASTSPE2genetic
27708008
MSH2_YEASTMSH2genetic
27708008
HMI1_YEASTHMI1genetic
27708008
YO098_YEASTYOL098Cgenetic
27708008
DDP1_YEASTDDP1genetic
27708008
AFT2_YEASTAFT2genetic
27708008
RO52_HUMANTRIM21physical
27107014
NADK_HUMANNADKphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YEF1_YEAST

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Related Literatures of Post-Translational Modification

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