CAF17_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAF17_YEAST
• UniProt AC: P47158
• Protein Name: Putative transferase CAF17, mitochondrial
• Gene Name: IBA57
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 497
• Subcellular Localization: Mitochondrion matrix .
• Protein Description: Required for lysine and glutamate prototrophy and mitochondrial genome maintenance. Has a role in the maturation of mitochondrial aconitase-type and radical-SAM Fe/S proteins biotin synthase and lipoic acid synthase..
• Protein Sequence: MFISRRCRIKGFTLKNLLWFRSSSTRFVSTESPDASAITKPDGIFNYSLLENRTYIRIRGPDTVKFLNGLVTSKLLPHFIKKNLTTVEENEVPTEEGTTKVDPIIPVPEFDARLGNWGLYNEKGIQGPYISRFGLYSAFLNGKGKLITDTIIYPTPVTVSEQISNYPEYLLELHGNVVDKILHVLQTHKLANKIKFEKIDHSSLKTWDVEVQFPNLPKDIENPWFDNLLDPMALPKNSIDANNFAVNVLNSLFNSDPRILGIYVERRTESMSRHYSTFPQSFRVVTSEQVDDLSKLFNFNVFDFPFQVNKKASVQVREIRFQKGLIDSTEDYISETLLPLELNFDFFPNTISTNKGCYVGQELTARTYATGILRKRLVPVKLDNYQLLDTDPERKYAEFHIDNVVEKSLAENEPTLNPFTNKPPERTKRKQRPAGLLISNEGLYGVALLRTEHFSAAFSSDEPVEFYITTTKGENIKITPQKPFWFSDWKNNNGPHK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
272	Phosphorylation	ERRTESMSRHYSTFP EECCHHHHHHHCCCC	25.78	28889911
395	Acetylation	LDTDPERKYAEFHID CCCCHHHHHEEEEHH	47.34	24489116
408	Phosphorylation	IDNVVEKSLAENEPT HHHHHHHHHHCCCCC	21.21	26447709
415	Phosphorylation	SLAENEPTLNPFTNK HHHCCCCCCCCCCCC	32.75	26447709
420	Phosphorylation	EPTLNPFTNKPPERT CCCCCCCCCCCCHHH	43.52	26447709

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CAF17_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAF17_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAF17_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ISA1_YEAST	ISA1	physical	18086897
ISA2_YEAST	ISA2	physical	18086897
MRX6_YEAST	YNL295W	physical	18467557
YN075_YEAST	YNR075C-A	physical	18467557
DUN1_YEAST	DUN1	genetic	26567217
CHK1_YEAST	CHK1	genetic	26567217

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.