ISA1_YEAST - dbPTM
ISA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ISA1_YEAST
UniProt AC Q07821
Protein Name Iron-sulfur assembly protein 1
Gene Name ISA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 250
Subcellular Localization Mitochondrion matrix.
Protein Description Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly..
Protein Sequence MINTGRSRNSVLLAHRFLSTGGFWRGGTNGTMSRTINNVNPFKLKFIPKTVPAAADSVSPDSQRPGKKPFKFIVSNQSKSSKASKSPKWSSYAFPSRETIKSHEEAIKKQNKAIDEQIAAAVSKNDCSCTEPPKKRKRKLRPRKALITLSPKAIKHLRALLAQPEPKLIRVSARNRGCSGLTYDLQYITEPGKFDEVVEQDGVKIVIDSKALFSIIGSEMDWIDDKLASKFVFKNPNSKGTCGCGESFMV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
59PhosphorylationPAAADSVSPDSQRPG
CCCCCCCCCCCCCCC
27.2625533186
62PhosphorylationADSVSPDSQRPGKKP
CCCCCCCCCCCCCCC
31.3225533186

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ISA1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ISA1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ISA1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RS26A_YEASTRPS26Aphysical
10688190
RS26B_YEASTRPS26Bphysical
10688190
YRA1_YEASTYRA1physical
16554755
RV167_YEASTRVS167physical
16554755
SC160_YEASTSCP160physical
16554755
NFU1_YEASTNFU1physical
16554755
YP216_YEASTYPL216Wphysical
16554755
CAF17_YEASTIBA57physical
18086897
HDA1_YEASTHDA1genetic
21288874
HDA2_YEASTHDA2genetic
21288874
COG4_YEASTCOG4genetic
21288874
VPS72_YEASTVPS72genetic
21288874
RU1C_YEASTYHC1genetic
27708008
RPB2_YEASTRPB2genetic
27708008
MED4_YEASTMED4genetic
27708008
FYV12_YEASTFYV12genetic
27708008
DPOA2_YEASTPOL12genetic
27708008
CDC27_YEASTCDC27genetic
27708008
CND2_YEASTBRN1genetic
27708008
PRP6_YEASTPRP6genetic
27708008
PRP9_YEASTPRP9genetic
27708008
DPOD_YEASTPOL3genetic
27708008
NSE4_YEASTNSE4genetic
27708008
CDC53_YEASTCDC53genetic
27708008
UBC3_YEASTCDC34genetic
27708008
GPI19_YEASTGPI19genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
RSC8_YEASTRSC8genetic
27708008
RPN12_YEASTRPN12genetic
27708008
CDC20_YEASTCDC20genetic
27708008
SWC4_YEASTSWC4genetic
27708008
TFC4_YEASTTFC4genetic
27708008
RPN1_YEASTRPN1genetic
27708008
ATC7_YEASTNEO1genetic
27708008
MCM10_YEASTMCM10genetic
27708008
PRI1_YEASTPRI1genetic
27708008
STS1_YEASTSTS1genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
NUP85_YEASTNUP85genetic
27708008
CDT1_YEASTTAH11genetic
27708008
PRI2_YEASTPRI2genetic
27708008
MIF2_YEASTMIF2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
SC61A_YEASTSEC61genetic
27708008
SEC65_YEASTSEC65genetic
27708008
ERB1_YEASTERB1genetic
27708008
TRM6_YEASTGCD10genetic
27708008
DPOA_YEASTPOL1genetic
27708008
MED7_YEASTMED7genetic
27708008
CLP1_YEASTCLP1genetic
27708008
BUR1_YEASTSGV1genetic
27708008
ORC4_YEASTORC4genetic
27708008
PGTB2_YEASTBET2genetic
27708008
CHK1_YEASTCHK1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
VPS41_YEASTVPS41genetic
27708008
CGR1_YEASTCGR1genetic
27708008
ICE2_YEASTICE2genetic
27708008
VPS53_YEASTVPS53genetic
27708008
YRA2_YEASTYRA2genetic
27708008
ESC1_YEASTESC1genetic
27708008
RNH2A_YEASTRNH201genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
CACO2_HUMANCALCOCO2physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ISA1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP