dbPTM

MRX6_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MRX6_YEAST
UniProt AC	P48564
Protein Name	MIOREX complex component 6 {ECO:0000305\|PubMed:25683707}
Gene Name	MRX6 {ECO:0000303\|PubMed:25683707}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	524
Subcellular Localization	Mitochondrion .
Protein Description	Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression..
Protein Sequence	MEHQALRRLVLYCPNFIRRGALRQNMTRVSCRHMSGKGGGRDEKGDCNEEKDSSKDLGRVPSKMKRAYDGETVIKEGDSHAESLAQQGKQPTDLAYNSRSKISGSNLHLLVPRVASTDYISNKEVHTEGLFAGYRPLFLGNSGFPSDARKGKNFHELDDVLPNIQVVDASEKDGKLNVQEIIEDLQRTSLRESIHSMEQLPSSHKRKPVIPWDASISGMVYNDMPFKYVPKNIILKMKPFKLLRIERKSQAKNARKPTMIKLQFHNRRINDTPELVNLYHNKSRLHESLYNTKPLQESGYSSANTSKRQKMLKARSDFEHKQKNYAYKHTFIKNDQELFRNELTKLNKILAREFKKLTKLSIHNEFKREHLPLAVYVSKSKGTKKLFRRSLKMKIMDHIYPVYTTILSTLTNSRDSKKFENKIKAYIEKIIVRLSDEVPSTYFFQDGVDCIIQPSPIHNFKRMHWLRYTKRHNTFWGRTIHKDVQVSFNDKYVVTRSGVRYTRYPTNLNTQLLETAFEEWDYYE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
35	Phosphorylation	RVSCRHMSGKGGGRD EEEEHHHCCCCCCCC		27017623
429	Ubiquitination	KIKAYIEKIIVRLSD HHHHHHHHHHHHHCC		19722269

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MRX6_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MRX6_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MRX6_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EIF3J_YEAST	HCR1	genetic	27708008
NCBP2_YEAST	CBC2	genetic	27708008
PEX22_YEAST	PEX22	genetic	27708008
RIF1_YEAST	RIF1	genetic	27708008
AGP1_YEAST	AGP1	genetic	27708008
CRD1_YEAST	CRD1	genetic	27708008
YD157_YEAST	YDL157C	genetic	27708008
YD514_YEAST	YDR514C	genetic	27708008
PEX14_YEAST	PEX14	genetic	27708008
VMA21_YEAST	VMA21	genetic	27708008
UBCX_YEAST	PEX4	genetic	27708008
RS27B_YEAST	RPS27B	genetic	27708008
GEF1_YEAST	GEF1	genetic	27708008
PAM17_YEAST	PAM17	genetic	27708008
UBP11_YEAST	UBP11	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
PEX15_YEAST	PEX15	genetic	27708008
SERC_YEAST	SER1	genetic	27708008
RS10A_YEAST	RPS10A	genetic	27708008
TRM44_YEAST	TRM44	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MRX6_YEAST

Related Literatures of Post-Translational Modification