UBP11_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UBP11_YEAST
• UniProt AC: P36026
• Protein Name: Ubiquitin carboxyl-terminal hydrolase 11
• Gene Name: UBP11
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 717
• Protein Sequence: MLLNPDQILNLVRKVYEVDIKQFYSQLRLKNLRGLLDHAAHLFNVYLRDLEINQEMEALTAFIIGCYYLYLIIPQSLQFQTRNNLYSSYAKLKNDYQDEHVMGYVLKVVRDESTVIVDRYLAESNGICRTIKRKRAYSLPLRPLPVHMASLSIHNKFDGSLHEIPNELTKPTNDNSKEDIVRESNQIASSNKLEAGSEVAYYTSKEALSKPSYLKLSTGKDALFKTLSSPATAPPVHSLEVSSQIRDSSQDSSSSLSKVEKPKEEEGKIEAIESSAPKAYNLPVIEDSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLFLNTNKYPKEVQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQEFLLIVLARIHEELSNENVVKYYPDLVSYDANALQVNPSKYEKWYERNVITDGLSPIDHIYRGQLENILKCQRCGNSSYSYSTFYVLSLAIPKLSLYSFTSKSRKIKLEDCINLFTGDEELSGDNAWDCPNCRITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSSDDSTKNAKKRNSKKLTTIKSLDFIVLPPILVIHLSRFYYDLTKKNSTVITYPLILNIILKNGKVIRYKLYGTVNHSGNLINGHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQHRKDRNNFEAGKTEMSSDEVYVLFYERMDEENYEEEFC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
138	Phosphorylation	IKRKRAYSLPLRPLP CCCCCCCCCCCCCCC	23.64	24961812
169	Phosphorylation	HEIPNELTKPTNDNS HCCCCCCCCCCCCCC	28.88	26447709
172	Phosphorylation	PNELTKPTNDNSKED CCCCCCCCCCCCHHH	57.68	26447709
176	Phosphorylation	TKPTNDNSKEDIVRE CCCCCCCCHHHHHHH	40.04	28889911
228	Phosphorylation	DALFKTLSSPATAPP CHHHHHCCCCCCCCC	39.24	28152593
229	Phosphorylation	ALFKTLSSPATAPPV HHHHHCCCCCCCCCC	22.97	25752575
248	Phosphorylation	VSSQIRDSSQDSSSS ECHHCCCCCCCCCCC	21.76	27017623
249	Phosphorylation	SSQIRDSSQDSSSSL CHHCCCCCCCCCCCC	42.15	27017623
252	Phosphorylation	IRDSSQDSSSSLSKV CCCCCCCCCCCCCCC	25.20	28889911
255	Phosphorylation	SSQDSSSSLSKVEKP CCCCCCCCCCCCCCC	38.31	28889911
617	Phosphorylation	KNSTVITYPLILNII CCCEEEEHHHHHEHH	5.73	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UBP11_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UBP11_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UBP11_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BMH2_YEAST	BMH2	physical	16554755
ATG1_YEAST	ATG1	physical	16554755
UBX1_YEAST	SHP1	genetic	17314980
SNF5_YEAST	SNF5	genetic	17314980
NOT2_YEAST	CDC36	genetic	17314980
SWI3_YEAST	SWI3	genetic	17314980
RPA34_YEAST	RPA34	genetic	17314980
PFD1_YEAST	PFD1	genetic	17314980
RL40_HUMAN	UBA52	physical	10527495
UBA3_YEAST	UBA3	genetic	27708008
BUD14_YEAST	BUD14	genetic	27708008
CYPR_YEAST	CPR4	genetic	27708008
BDF2_YEAST	BDF2	genetic	27708008
SSB1_YEAST	SSB1	genetic	27708008
SOK1_YEAST	SOK1	genetic	27708008
CWC15_YEAST	CWC15	genetic	27708008
CEM1_YEAST	CEM1	genetic	27708008
IES1_YEAST	IES1	genetic	27708008
MUP1_YEAST	MUP1	genetic	27708008
MIC26_YEAST	MIC26	genetic	27708008
YHK5_YEAST	YHR045W	genetic	27708008
STB5_YEAST	STB5	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
SWE1_YEAST	SWE1	genetic	27708008
PHD1_YEAST	PHD1	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
AVT3_YEAST	AVT3	genetic	27708008
SPA2_YEAST	SPA2	genetic	27708008
UBI4P_YEAST	UBI4	genetic	27708008
RAX2_YEAST	RAX2	genetic	27708008
RFX1_YEAST	RFX1	genetic	27708008
MMS22_YEAST	MMS22	genetic	27708008
PUR1_YEAST	ADE4	genetic	27708008
RNH2A_YEAST	RNH201	genetic	27708008
TRM11_YEAST	TRM11	genetic	27708008
VAM10_YEAST	VAM10	genetic	27708008
VAM3_YEAST	VAM3	genetic	27708008
CHL1_YEAST	CHL1	genetic	27708008
SGF11_YEAST	SGF11	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
WDR6_YEAST	RTT10	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.