NTA1_YEAST - dbPTM
NTA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NTA1_YEAST
UniProt AC P40354
Protein Name Protein N-terminal amidase
Gene Name NTA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 457
Subcellular Localization
Protein Description Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway..
Protein Sequence MLIDAIHGAKMSTKLLVSLKVLVIQLNPQIGQVDQTIKRTWSILDKVTKSATYVKPDIILFPEFALTGYSFHARKDILPYVTKKDEGPSFELAKSISEKFQCYTIIGYPEDDDEQKLYNSALVVNPQGEQIFNYRKTFLYDTEMNWDCEENPEGFQTFPMDFSKCAKLSNEDSYNRDVTLKASIGICMDLSPYKFMAPFNHFEFSSFCVDNNVELILCPMAWLNSTSITDKQTLHNNSLLEAAKNKIAFALKEQGLPLAGSQGIYQLKIGDSQRTPRVPSDDSTSEYKDMDEPDMSNVNYWILRFFPFLYFKSRINWFKNSSLIESILGKTRMPLDHEYYKDGKHKEDTIDLLDSEEVIKDTVLEKTFLGTSLGQPWKFQGKNAILVLANRCGTEDGTTIFAGSSGIYKFNGKKPKGSQDDDESSLDSLNESVELLGNLGKGLEGAILREVQFEVFR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
18PhosphorylationMSTKLLVSLKVLVIQ
CCHHHHHHHEEEEEE		23.5719684113
42PhosphorylationQTIKRTWSILDKVTK
HHHHHHHHHHHHHCC		16.8021440633
183PhosphorylationRDVTLKASIGICMDL
CCCEEEEEEEEEECC		21.5427017623
191PhosphorylationIGICMDLSPYKFMAP
EEEEECCCCCCEEEC		23.1727017623
252UbiquitinationNKIAFALKEQGLPLA
HHHHHHHHHCCCCCC		44.5624961812
283PhosphorylationPRVPSDDSTSEYKDM
CCCCCCCCCCCCCCC		38.5322369663
284PhosphorylationRVPSDDSTSEYKDMD
CCCCCCCCCCCCCCC		32.3522369663
285PhosphorylationVPSDDSTSEYKDMDE
CCCCCCCCCCCCCCC		42.7722369663
319UbiquitinationKSRINWFKNSSLIES
HHHCCHHHCHHHHHH		47.7523749301
394PhosphorylationVLANRCGTEDGTTIF
EEECCCCCCCCCEEE		34.2329688323
398PhosphorylationRCGTEDGTTIFAGSS
CCCCCCCCEEEECCC		29.1029688323
399PhosphorylationCGTEDGTTIFAGSSG
CCCCCCCEEEECCCC		21.4529688323
404PhosphorylationGTTIFAGSSGIYKFN
CCEEEECCCCEEEEC		23.2029688323
405PhosphorylationTTIFAGSSGIYKFNG
CEEEECCCCEEEECC		28.4329688323
408PhosphorylationFAGSSGIYKFNGKKP
EECCCCEEEECCCCC		17.0429688323
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NTA1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NTA1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NTA1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VATA_YEASTVMA1physical
11805837
IPYR_YEASTIPP1physical
11805837
VATE_YEASTVMA4physical
11805837
MDHM_YEASTMDH1physical
11805837
HSP7E_YEASTECM10physical
11805837
GRPE_YEASTMGE1physical
11805837
HS104_YEASTHSP104physical
11805837
SSB1_YEASTSSB1physical
19536198
CDC37_YEASTCDC37genetic
27708008
GNA1_YEASTGNA1genetic
27708008
SHG1_YEASTSHG1genetic
27708008
TFS2_YEASTDST1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
RL8A_YEASTRPL8Agenetic
27708008
TIM22_YEASTTIM22genetic
27708008
PHB2_YEASTPHB2genetic
27708008
YHY2_YEASTYHR182Wgenetic
27708008
TDA1_YEASTTDA1genetic
27708008
DOCK8_HUMANDOCK8physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NTA1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory