dbPTM

NAA35_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NAA35_YEAST
UniProt AC	Q02197
Protein Name	N-alpha-acetyltransferase, 35 NatC auxiliary subunit
Gene Name	MAK10
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	733
Subcellular Localization	Cytoplasm .
Protein Description	Component of the NatC N-terminal acetyltransferase, which catalyzes acetylation of the N-terminus Met of L-A virus Gag protein. MAK10 has a role in the propagation of L-A and M viruses, perhaps in the viral assembly. It is apparently directly needed for optimum respiration..
Protein Sequence	MEVDSILGSLSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLDSSLIELTAEEIEFDVNVAYDPPLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNNMGFNTFDNLPGQDVVINSLTESLQILEAYSDDSLHLTMLKHILKIIICLVHLEDHLTDYSTKTSHLDELIENANSVNGIFPQLQLSPPKGAFSTYIQKHRSNQFPPRKITKLPTDYSGFITLANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEFSAQTPSEFESSIGNELIQESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDSLQAQFESVNSQVYCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETFLKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLLKEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPEYEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYFPIQTLRIKQDRYK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
358	Phosphorylation	TVLGKFSYTQFYLLH EEEEECEEEEEEEEE	14.00	28132839
362	Phosphorylation	KFSYTQFYLLHVKEF ECEEEEEEEEEEEEC	9.87	28132839

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NAA35_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NAA35_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NAA35_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XRN1_YEAST	XRN1	genetic	6987655
NAA30_YEAST	MAK3	physical	18719252
HMS1_YEAST	HMS1	physical	18719252
UBC3_YEAST	CDC34	genetic	21940857
ICE2_YEAST	ICE2	genetic	27708008
RCY1_YEAST	RCY1	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
EIF3J_YEAST	HCR1	genetic	27708008
MNN2_YEAST	MNN2	genetic	27708008
CSG2_YEAST	CSG2	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
RPN4_YEAST	RPN4	genetic	27708008
ATG31_YEAST	ATG31	genetic	27708008
TRS85_YEAST	TRS85	genetic	27708008
SWI5_YEAST	SWI5	genetic	27708008
NUM1_YEAST	NUM1	genetic	27708008
DOT1_YEAST	DOT1	genetic	27708008
SNF1_YEAST	SNF1	genetic	27708008
COG7_YEAST	COG7	genetic	27708008
ERV14_YEAST	ERV14	genetic	27708008
MDM34_YEAST	MDM34	genetic	27708008
CHO2_YEAST	CHO2	genetic	27708008
OCA5_YEAST	OCA5	genetic	27708008
GOSR1_YEAST	GOS1	genetic	27708008
DAL81_YEAST	DAL81	genetic	27708008
PEP8_YEAST	PEP8	genetic	27708008
VPS35_YEAST	VPS35	genetic	27708008
RAV1_YEAST	RAV1	genetic	27708008
MMM1_YEAST	MMM1	genetic	27708008
RIC1_YEAST	RIC1	genetic	27708008
YPT6_YEAST	YPT6	genetic	27708008
NKP2_YEAST	NKP2	genetic	27708008
COG8_YEAST	COG8	genetic	27708008
AIM34_YEAST	AIM34	genetic	27708008
COG6_YEAST	COG6	genetic	27708008
COG5_YEAST	COG5	genetic	27708008
MDM12_YEAST	MDM12	genetic	27708008
VAM10_YEAST	VAM10	genetic	27708008
GYP1_YEAST	GYP1	genetic	27708008
RUD3_YEAST	RUD3	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
AIM44_YEAST	AIM44	genetic	27708008
YP091_YEAST	NVJ2	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NAA35_YEAST

Related Literatures of Post-Translational Modification